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Adrenal antibody test for women experiencing unexplained fatigue and autoimmune symptoms

Blood Test for Unexplained Fatigue and Weakness

Adrenal Antibody Screen with Reflex to Titer

Google
3,138 reviews
  • Pinpoint the cause of your fatigue
  • Reveal hidden adrenal issues effortlessly
  • Clarify unexplained weight changes quickly
First results as soon as overnight*

90 day happiness guarantee

We stand behind our service

Prescription & fees included

Go directly to the lab, no extra fees

Easy to understand results

With friendly doctor's notes & guidance

Fast & convenient

Lab visit as quick as 10 mins in & out

90 day happiness guarantee

We stand behind our service

Prescription & fees included

Go directly to the lab, no extra fees

Easy to understand results

With friendly doctor's notes & guidance

Fast & convenient

Lab visit as quick as 10 mins in & out

What's this test for?

This test is ideal if you're experiencing unexplained fatigue, weakness, weight loss, low blood pressure, or dizziness that won't go away. It helps detect Addison's disease, an autoimmune condition where your immune system attacks your adrenal glands, affecting your body's ability to manage stress and maintain energy. Many people use this test when they have persistent symptoms that suggest adrenal problems but want concrete answers about whether an autoimmune process is involved.

How should I prepare for this test?

No special preparation is typically required for this antibody test. You can take your regular medications and eat normally before the test. However, if you're on immunosuppressive medications or steroids, let your healthcare provider know as these may affect antibody levels. Simply schedule your appointment and arrive at the lab for a standard blood draw.

What's included in this test?

Adrenal Ab Adrenal Ab, Titer

This test measures adrenal antibodies (Adrenal Ab) and their concentration level (Adrenal Ab, Titer) to detect whether your immune system is producing antibodies that attack your adrenal glands. These antibodies are the hallmark of autoimmune Addison's disease, which can cause chronic fatigue, weakness, and hormonal imbalances. Together, these measurements help identify if an autoimmune process is affecting your adrenal function and contributing to your symptoms.

What happens after I get my results?
You'll receive detailed doctor notes in simple language explaining what your adrenal antibody levels mean for your energy, stress response, and overall health. These notes include personalized recommendations like lifestyle modifications, when to seek endocrinology consultation, or whether additional adrenal function testing is needed. You'll also get the standard lab report and can track your antibody levels over time using our trends feature to monitor any changes in your autoimmune status.
When will I get my results?
Most adrenal antibody test results are available within 3-5 business days after your blood is drawn at the lab. The testing requires specialized antibody detection methods, which take a bit longer than routine blood work. You'll receive an email notification as soon as your results are ready to view in your secure online account.
Who should consider getting this test?
This test is important for anyone experiencing persistent unexplained fatigue, weakness, weight loss, low blood pressure, salt cravings, or darkening of the skin. It's especially relevant if you have other autoimmune conditions like type 1 diabetes, thyroid disease, or vitiligo, as these increase your risk. People with a family history of Addison's disease or autoimmune disorders should also consider this test if they're experiencing suggestive symptoms.
What symptoms indicate I may need this test?
Key symptoms include chronic fatigue that doesn't improve with rest, muscle weakness, unintended weight loss, low blood pressure causing dizziness, salt cravings, and darkening of skin in creases and scars. You may also experience nausea, vomiting, diarrhea, irritability, or depression. If you have several of these symptoms persistently, especially if they worsen during stress or illness, this test can help identify if autoimmune adrenal damage is the cause.
How can I naturally support my adrenal health?
While you cannot reverse autoimmune adrenal damage naturally, you can support overall adrenal function through stress management techniques like meditation, deep breathing, or yoga. Prioritize 7-9 hours of quality sleep, eat regular balanced meals with adequate salt intake, and stay well-hydrated. Avoid extreme diets or excessive caffeine, and consider adaptogenic herbs like ashwagandha or rhodiola after consulting with your healthcare provider.
What are adrenal antibodies and why do they matter?
Adrenal antibodies are proteins your immune system creates that mistakenly attack your adrenal glands, which sit on top of your kidneys and produce essential stress hormones like cortisol. When these antibodies are present, they can gradually destroy adrenal tissue, leading to Addison's disease where your body can't produce enough cortisol and aldosterone. Detecting these antibodies early helps identify the autoimmune cause and allows for proper monitoring and treatment before serious complications develop.
What does a positive adrenal antibody result mean?
A positive result means your immune system is producing antibodies against your adrenal glands, which strongly suggests autoimmune Addison's disease. This indicates ongoing autoimmune activity that may be damaging your adrenal tissue and affecting hormone production. A positive result typically requires follow-up testing of adrenal hormone levels and consultation with an endocrinologist to assess the extent of adrenal function impairment and determine if hormone replacement therapy is needed.
How often should I retest adrenal antibodies?
If your initial test is positive, your doctor may retest periodically to monitor antibody levels alongside adrenal function tests, typically every 6-12 months. If your initial test is negative but you continue to have symptoms, retesting may be considered in 6-12 months since antibodies can develop over time. Once diagnosed with autoimmune Addison's disease, monitoring focuses more on hormone levels than antibody titers, though occasional antibody testing may help track disease progression.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at [email protected], and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at [email protected]. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email [email protected].
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email [email protected].

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

You get clinical lab reports & simplified health insights.
Save time & gas, go straight to the lab. Our doctors cover the rest.
Results start landing the next day after your lab visit.*
We don’t sell or share your data. Your time & privacy matter.
US-licensed doctors have your back if things get unclear.
No hidden fees, nice discounts for regular checkups.
Save a trip to the doctor, go directly to the lab
Instant orders, results often overnight*
Results explained in simple language
Reviewed by US licensed doctors
Fast & confidential, we never sell or share your data
No insurance needed, transparent pricing
Demo results
Adrenal Antibody Negative
Demo results
Negative Positive
Negative

What this means

Your test came back negative, meaning no adrenal antibodies were detected in your blood. This is the expected and healthy result, indicating that your immune system is not attacking your adrenal glands and autoimmune Addison's disease is unlikely to be the cause of your symptoms.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More complex tests, such as hormone panels, may take up to 10–15 business days due to their complexity.
Here’s how easy it is to get blood work done on your terms
Choose a checkup
Order your test Save a trip to the doctor. Your results will come with clear, friendly explanations. Takes 2 minutes
Book a lab
Book an appointment Visit any of our 4,000 nearby lab locations to have your samples collected. Book or walk-in
Choose a checkup
Get results Receive a clear, easy-to-digest health report by email & SMS within a few business days. Get answers, fast

Blood Test for Unexplained Fatigue and Weakness

Google
3,138 reviews
  • Pinpoint the cause of your fatigue
  • Reveal hidden adrenal issues effortlessly
  • Clarify unexplained weight changes quickly

1,000,000+ blood tests later, here's what our customers say

Google reviews 3138 reviews Next
Still got questions? Text our super-cool support team at 754-799-7833 to get help finding your ideal checkup.