Addison's disease occurs when the adrenal glands (located above each kidney) do not work normally and do not produce enough hormones. Addison's disease may also be called chronic adrenal insufficiency or hypocortisolism.
This screen is used to aid in the diagnosis of Addison's disease.
Significant deviations from the normal range may require further evaluation by your physician.
Adrenocorticotropic Hormone (ACTH), Plasma;
Antiadrenal Antibodies, Quantitative;
Uric Acid, serum;
Urinalysis: Color, appearance, specific gravity, pH, protein, glucose, occult blood, ketones, leukocyte esterase, nitrite, bilirubin, urobilinogen, and microscopic examination of urine sediment;
CBC With Differential/Platelet: Hematocrit; hemoglobin; mean corpuscular volume (MCV); mean corpuscular hemoglobin (MCH); mean corpuscular hemoglobin concentration (MCHC); red cell distribution width (RDW); percentage and absolute differential counts; platelet count; red cell count; white blood cell count.
Comprehensive Metabolic Profile (CMP) (includes eGFR): A:G ratio; albumin, serum; alkaline phosphatase, serum; ALT (SGPT); AST (SGOT); bilirubin, total; BUN; BUN:creatinine ratio; calcium, serum; carbon dioxide, total; chloride, serum; creatinine, serum; globulin, total; glucose, serum; potassium, serum; protein, total, serum; sodium, serum; eGFR.
Patient should fast for 12 hours prior to specimen collection. ACTH should be drawn between 7 AM and 10 AM. Some tests in this panel may exhibit interference when sample is collected from a person who is consuming a supplement with a high dose of biotin (also termed as vitamin B7 or B8, vitamin H or coenzyme R). It is recommended to stop biotin consumption at least 72 hours prior to the collection of specimen.
Estimated turnaround for results is 7 business days. If confirmation testing is required, the estimated time may be extended.