Testosterone, Total, Male, IA (MALES ONLY) - (QUEST DIAGNOSTICS)
Testosterone circulates almost entirely bound to transport proteins: Normally less than 1-2% is free. The principal transport protein for testosterone is known as sex hormone binding globulin (SHBG) or testosterone-estradiol binding globulin (TeBG). Testosterone measurements are used to assess erectile dysfunction, infertility, gynecomastia, and osteoporosis and to assess hormone replacement therapy.
This is a Male Only Testosterone test, it cannot be performed on a female. FEMALES needing to order this test from Quest will need to order the 'Testosterone Total LC/MS/MS'.
Use of synthetic steroids, various supplements and/or high doses of biotin may interfere with the accuracy of the standard immunoassay Testosterone Total serum test. If you are taking any of these it is recommended that you order the Testosterone Total LC/MS/MS for testing.
This testosterone test will also provide results when the total testosterone value is >1500 but <3,000.
This is a Male Only test, it cannot be ordered by females. If a female orders this panel, the testosterone test will not be included on the requisition or performed at the lab.
Significant deviations from the normal range may require further evaluation by your physician.
Total Testosterone
If using a testosterone cream please be sure you have not rubbed any into the antecubital area of your arm for the last 24 hours as it can give elevated results. Estimated turnaround for results is 3 business days. If confirmation testing is required, the estimated time may be extended.
Testosterone testing is used to evaluate androgen excess or deficiency related to gonadal function, adrenal function, or tumor activity. Testosterone levels may be helpful in men for the diagnosis of hypogonadism, hypopituitarism, Klinefelter syndrome, and impotence (low values). Testosterone levels may be requested in women to investigate the cause of hirsutism, anovulation, amenorrhea, virilization, masculinizing tumors of the ovary, tumors of the adrenal cortices, and congenital adrenal hyperplasia (high values). Testosterone levels in children may be helpful to investigate issues related to puberty and development as well as the aforementioned.
For testosterone measurements in females or expected levels >1500, use of Testosterone, Total, Women, Children, and Hypogonadal Males, LC/MS-MS, which employs liquid chromatography/tandem mass spectrometry (LC/MS-MS), is recommended.
Use of synthetic steroids, various supplements and/or high doses of biotin may interfere with the accuracy of the standard immunoassay Testosterone Total serum test. If you are taking any of these it is recommended that you order the Testosterone, Total, Women, Children, and Hypogonadal Males, LC/MS-MS for testing.
Significant deviations from the normal range may require further evaluation by your physician.
Total Testosterone
Note: If total testosterone results are expected to be >1500 it is best that the Testosterone LC/MS-MS version of this test be ordered. Reporting values that exceed 1500 will now be reported as >1500 for all regions, as this standard operating procedure will now be nationwide.
If using a testosterone cream please be sure you have not rubbed any into the antecubital area of your arm for the last 24 hours as it can give elevated results. This test may exhibit interference when sample is collected from a person who is consuming a supplement with a high dose of biotin (also termed as vitamin B7 or B8, vitamin H or coenzyme R). It is recommended to stop biotin consumption at least 72 hours prior to the collection of specimen. Estimated turnaround for results is 3 business days. If confirmation testing is required, the estimated time may be extended.