Follicle-stimulating Hormone (FSH) and Luteinizing Hormone (LH)
- (QUEST DIAGNOSTICS)Description:
FSH/LH testing is used in the workup of infertility (for both men and women). Used also to investigate low sperm count, menstrual irregularities, pitutary disorders, diseases involving the testes or ovaries. May be used to determine the cause of early or delayed puberty.
FSH and LH are secreted by the anterior pituitary in response to gonadotropin-releasing hormone (GNRH) secreted by the hypothalamus. In both males and females, FSH and LH secretion is regulated by a balance of positive and negative feedback mechanisms involving the hypothalamic-pituitary axis, the reproductive organs, and the pituitary and sex steroid hormones. FSH and LH play a critical role in maintaining the normal function of the male and female reproductive systems. Abnormal FSH levels with corresponding increased or decreased levels of LH, estrogens, progesterone, and testosterone are associated with a number of pathological conditions. Increased FSH levels are associated with menopause and primary ovarian hypofunction in females and primary hypogonadism in males. Decreased levels of FSH are associated with primary ovarian hyper-function in females and primary hypergonadism in males. Normal or decreased levels of FSH are associated with polycystic ovary disease in females. In males, LH is also called interstitial cell-stimulating hormone (ICSH). Abnormal LH levels with corresponding increased or decreased levels of FSH, estrogens, progesterone, and testosterone are associated with a number of pathological conditions. Increased LH levels are associated with menopause, primary ovarian hypofunction, and polycystic ovary disease in females and primary hypo-gonadism in males. Decreased LH levels are associated with primary ovarian hyperfunction in females and primary hyper-gonadism in males.
A significant deviation from the normal range may require further evaluation by your physician.Includes: Follicle-stimulating Hormone (FSH)
and Luteinizing Hormone (LH)Categories: Female Specific Tests
, Infertility Testing
, Hormones and Metabolism