Understanding Lab Tests for Latent Tuberculosis
Written by Private MD Labs Medical Writing Team • Last Updated: September 8, 2025
Latent tuberculosis infection (LTBI) occurs when a person is infected with Mycobacterium tuberculosis bacteria but does not have active disease or symptoms. Unlike active TB, latent TB cannot be diagnosed through symptoms or physical examination alone, making specialized blood testing essential for detection.
Recommended Test
QuantiFERON®-TB Gold Plus
This advanced blood test is specifically designed to detect latent tuberculosis infection by measuring the immune system's response to TB bacteria. The test can identify the presence of Mycobacterium tuberculosis in individuals who do not have active disease, making it an essential tool for early detection and prevention of TB progression.
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Why Blood Testing is Critical for Latent TB
People with latent TB feel healthy and show no symptoms, yet they carry the TB bacteria in their bodies. Without proper testing, latent TB can remain undetected for years and may eventually develop into active tuberculosis disease. Blood tests are fundamental for identifying this hidden infection and determining who would benefit from preventive treatment.
Understanding Your Results
A positive QuantiFERON®-TB Gold Plus result indicates that you have been infected with TB bacteria and may have latent tuberculosis. This does not mean you have active TB disease, but it does mean you should discuss preventive treatment options with your healthcare provider to reduce the risk of developing active tuberculosis in the future.
Important Considerations
The information here is for educational purposes only and is not a substitute for professional medical advice. Always consult with a healthcare provider for diagnosis and treatment.
