Understanding Lab Tests for Latent TB Infection

Written by Private MD Labs Medical Writing Team Last Updated: September 8, 2025

Latent tuberculosis (TB) infection occurs when TB bacteria remain dormant in the body without causing symptoms or illness. Unlike active TB disease, people with latent TB infection feel well, show no symptoms, and cannot spread the infection to others. However, without proper treatment, latent TB can progress to active TB disease, making early detection crucial.

Recommended Test

QuantiFERON®-TB Gold Plus

This advanced blood test is specifically designed to identify latent TB infection by measuring the immune system's response to TB bacteria. The test is highly accurate and helps healthcare providers determine who needs preventive treatment to prevent progression from latent infection to active TB disease.

HSA/FSA accepted HSA/FSA accepted
Google reviews 2907 reviews
$425

Why Blood Testing is Essential for Latent TB Detection

Since latent TB infection produces no symptoms, specialized blood tests are the primary method for identification. These tests detect the body's immune response to TB bacteria, allowing healthcare providers to identify individuals who need preventive treatment to avoid progression to active TB disease.

Who Should Consider Testing

Testing for latent TB infection is particularly important for individuals at higher risk, including those who have been in close contact with someone with active TB, people from countries with high TB rates, healthcare workers, and individuals with compromised immune systems. Early detection allows for preventive treatment that can significantly reduce the risk of developing active TB disease.

Important Considerations

The information here is for educational purposes only and is not a substitute for professional medical advice. Always consult with a healthcare provider for diagnosis and treatment recommendations.

References