Understanding Lab Tests for Herpes Simplex Virus Type 2 (HSV-2)

Written by Private MD Labs Medical Writing Team • Last Updated: September 8, 2025

Herpes Simplex Virus Type 2 (HSV-2) is a sexually transmitted infection that primarily causes genital herpes. The infection is characterized by painful blisters and sores in the genital region. Many people with HSV-2 may not experience symptoms or have very mild symptoms, making blood testing essential for accurate diagnosis.

Recommended Test

Herpes Simplex Virus 2 (IgG), Type-Specific Antibody

This blood test detects IgG antibodies specific to HSV-2, providing clear evidence of past or current infection with the herpes simplex virus type 2. The presence of these antibodies indicates that the immune system has encountered HSV-2, confirming infection status even when symptoms are absent or mild.

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Diagnosing HSV-2 Infection

While HSV-2 can sometimes be diagnosed through physical examination during an active outbreak, many infections are asymptomatic or produce mild symptoms that may go unnoticed. Blood testing for type-specific antibodies provides a reliable method to determine if someone has been infected with HSV-2, regardless of symptom presence.

Understanding Your Results

A positive HSV-2 IgG antibody test indicates that you have been infected with HSV-2 at some point. This test is highly specific for HSV-2 and helps distinguish it from HSV-1, which typically causes oral herpes. Results can guide appropriate treatment decisions and help prevent transmission to partners.

Important Considerations

The information here is for educational purposes only and is not a substitute for professional medical advice. Always consult with a healthcare provider for diagnosis, treatment, and guidance on managing HSV-2 infection.

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