Understanding Lab Tests for Glomerulonephritis
Written by Private MD Labs Medical Writing Team • Last Updated: September 8, 2025
Glomerulonephritis is an inflammation of the glomeruli, the tiny filtering units within the kidneys. This condition can affect kidney function and lead to serious complications if left untreated. While the diagnosis involves multiple factors including clinical presentation and sometimes imaging, blood and urine tests play a crucial role in identifying the inflammatory process and monitoring kidney damage.
Top Recommended Test
Microalbumin, Random Urine with Creatinine
This test measures the albumin-to-creatinine ratio in urine, which becomes elevated when the kidney's filtering units (glomeruli) are damaged. An increased ratio suggests that protein is leaking through the damaged glomerular filters, which is a key indicator of glomerulonephritis and helps assess the extent of kidney damage.
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How Lab Tests Help Diagnose Glomerulonephritis
Laboratory testing is fundamental for detecting the inflammatory markers and kidney dysfunction associated with glomerulonephritis. These tests can reveal complement system activation, measure protein leakage through damaged kidney filters, and help healthcare providers assess the severity of the condition and monitor treatment response.
Other Relevant Tests
Complement Component C4c
This test measures C4c levels in the blood, which can be decreased in glomerulonephritis. During the inflammatory process affecting the kidney glomeruli, complement proteins like C4c are consumed as part of the immune response, leading to lower blood levels that can help indicate active inflammation.
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Complement Component C1q
This test measures C1q levels, which are often elevated in glomerulonephritis patients. High C1q levels are found in the kidneys during this condition and are believed to contribute to the inflammatory damage of kidney tissues, making this an important marker for assessing disease activity.
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Understanding Your Results
Test results should always be interpreted by a qualified healthcare provider who can consider them alongside your symptoms, medical history, and other diagnostic findings. These tests help confirm the diagnosis of glomerulonephritis and guide appropriate treatment to protect kidney function.
Important Considerations
The information here is for educational purposes only and is not a substitute for professional medical advice. Always consult with a healthcare provider for diagnosis and treatment of glomerulonephritis or any kidney-related concerns.
