Understanding Lab Tests for Giant Cell Arteritis

Written by Private MD Labs Medical Writing Team • Last Updated: September 8, 2025

Giant Cell Arteritis (GCA) is a form of vasculitis that causes inflammation of large and medium-sized arteries, particularly those in the head and neck. While there is no single blood test that can definitively diagnose Giant Cell Arteritis, laboratory testing plays a crucial role in assessing inflammation levels and monitoring disease activity.

Recommended Test

Interleukin-6 (IL-6), Serum

IL-6 is a key inflammatory marker that plays an important role in the development and progression of Giant Cell Arteritis. Elevated serum IL-6 levels can indicate active disease and ongoing inflammation in the arterial walls. This test is valuable for assessing disease activity and monitoring response to anti-inflammatory treatments.

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The Role of Blood Testing in Giant Cell Arteritis

Giant Cell Arteritis diagnosis typically relies on clinical symptoms, physical examination, and sometimes tissue biopsy. However, blood tests are fundamental for evaluating the inflammatory response in the body, supporting the diagnostic process, and monitoring treatment effectiveness. These tests help healthcare providers understand the severity of inflammation and track how well patients respond to therapy.

Understanding Your Results

Elevated IL-6 levels may suggest active inflammation consistent with Giant Cell Arteritis, but results must always be interpreted in the context of clinical symptoms and other diagnostic findings. Your healthcare provider will use these results alongside other information to guide treatment decisions and monitor your condition over time.

Important Considerations

The information here is for educational purposes only and is not a substitute for professional medical advice. Always consult with a healthcare provider for diagnosis and treatment.

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