Written by Private MD Labs Medical Writing Team • Last Updated: September 8, 2025
Gastrointestinal (GI) bleeding is a serious condition involving blood loss anywhere in the digestive tract, from the esophagus to the rectum. While the diagnosis is typically made through clinical examination and imaging procedures, blood tests play a crucial role in monitoring complications and identifying potential underlying causes or contributing factors.
This test measures blood urea nitrogen levels, which can become elevated when bleeding occurs in the gastrointestinal tract. As blood is digested and absorbed in the intestines, it serves as a source of urea, leading to increased BUN levels. Monitoring BUN helps healthcare providers assess the severity and impact of GI bleeding on kidney function and overall metabolic status.
Although there isn't a single blood test to diagnose gastrointestinal bleeding itself, laboratory testing is fundamental for assessing the body's response to blood loss, monitoring complications, and evaluating potential medication-related risks that may contribute to bleeding episodes.
This specialized test evaluates acetaminophen metabolism and related biomarkers. Chronic use of high doses of acetaminophen may increase the risk of upper gastrointestinal complications, including stomach bleeding. Elevated biomarker levels detected through this test may indicate potential medication-related contributions to GI bleeding, helping identify an important risk factor that requires medical attention.
Blood test results in the context of gastrointestinal bleeding provide valuable information about how your body is responding to blood loss and whether medications may be contributing to the problem. Elevated BUN levels may indicate ongoing bleeding, while abnormal acetaminophen-related biomarkers could suggest medication-induced complications.
The information here is for educational purposes only and is not a substitute for professional medical advice. Gastrointestinal bleeding requires immediate medical attention. Always consult with a healthcare provider for proper diagnosis, treatment, and monitoring of this serious condition.