Written by Private MD Labs Medical Writing Team • Last Updated: September 8, 2025
Gangrene is a serious medical condition involving the death of body tissue, typically diagnosed through physical examination and imaging studies. While there is no specific blood test to diagnose gangrene itself, laboratory testing plays a crucial role in monitoring the extent of tissue damage and assessing the body's response to this condition.
This enzyme test can be elevated in gangrene due to the breakdown of dying tissue, which releases aldolase into the bloodstream. Monitoring aldolase levels helps assess the extent of tissue damage and can provide valuable information about the severity of the condition and the body's response to treatment.
When tissue dies due to gangrene, cellular components are released into the bloodstream. Blood tests are fundamental for monitoring these biochemical changes, assessing the severity of tissue breakdown, and helping healthcare providers track the progression of the condition and response to treatment.
Elevated aldolase levels in the context of gangrene reflect ongoing tissue destruction. However, these results must be interpreted alongside clinical findings and other diagnostic methods. The test serves as a supporting tool rather than a primary diagnostic method for gangrene.
The information here is for educational purposes only and is not a substitute for professional medical advice. Gangrene is a medical emergency requiring immediate professional care. Always consult with a healthcare provider for diagnosis and treatment.