Coriander/cilantro allergy is an immune system reaction to proteins found in the coriander plant and its leaves (cilantro). It is caused by the production of immunoglobulin E (IgE) antibodies that target specific proteins in coriander and cilantro, triggering allergic symptoms ranging from mild skin reactions to severe anaphylaxis. The Coriander/Cilantro (f317) IgE test is the most important test for diagnosis because it specifically measures the antibodies responsible for allergic reactions.
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Coriander/cilantro allergy is caused by an overreaction of the immune system to specific proteins found in the coriander plant (seeds) and cilantro (leaves). When you consume or come into contact with these herbs, your immune system mistakenly identifies certain proteins as harmful invaders and produces immunoglobulin E (IgE) antibodies to attack them. This immune response triggers the release of histamine and other chemicals that cause allergic symptoms, which can range from mild itching and hives to severe reactions like difficulty breathing or anaphylaxis.
The Coriander/Cilantro (f317) IgE test is the most important test for coriander/cilantro allergy because it specifically measures the IgE antibodies your body produces in response to coriander and cilantro proteins. This blood test provides definitive confirmation that your symptoms are caused by an allergic reaction rather than food intolerance or other digestive issues. The test results are reported in classes or numerical values, with higher levels indicating greater allergic sensitization. Your healthcare provider can use these results to confirm the diagnosis, assess the severity of your allergy, and develop an appropriate management plan including dietary restrictions and emergency preparedness protocols.
You should get tested if you experience symptoms like itching, hives, swelling of the lips or tongue, difficulty breathing, or stomach upset after eating foods containing coriander or cilantro. Testing is also important if you have a history of reactions to other herbs or spices in the same family (such as parsley, caraway, or fennel), as cross-reactivity is common. You should seek testing before the allergy worsens or if you have experienced increasingly severe reactions over time. Early diagnosis helps you avoid these ingredients safely and prepare for potential accidental exposures with proper emergency medications.
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What this means
Your test shows positive IgE antibodies to cilantro/coriander, indicating your immune system has developed a sensitivity to this herb. This result suggests that cilantro may be contributing to your allergic symptoms such as digestive discomfort, skin reactions, or respiratory issues when you consume foods containing this ingredient.
Recommended actions
Avoid all foods containing cilantro leaves and coriander seeds, including Mexican, Asian, and Middle Eastern dishes
Read ingredient labels carefully and inform restaurant staff about your sensitivity when dining out
Consider using alternative herbs like parsley, basil, or cumin in recipes that call for cilantro
Keep antihistamines available for accidental exposure and consult an allergist for a comprehensive food allergy evaluation
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