Understanding Lab Tests for Complement Component 4 Deficiency
Written by Private MD Labs Medical Writing Team • Last Updated: September 8, 2025
Complement Component 4 Deficiency is a rare genetic disorder that affects the immune system's ability to fight infections and clear immune complexes. This condition is characterized by the body's inability to produce adequate amounts of the C4 protein, which is essential for proper immune function.
Recommended Test
Complement Component C4c
This test directly measures the levels of C4c protein in the blood, which is essential for diagnosing Complement Component 4 Deficiency. Individuals with this rare genetic disorder will show characteristically low levels of C4c because their bodies cannot produce sufficient amounts of this critical immune system protein.
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Diagnosing Complement Component 4 Deficiency
Since this is a genetic condition affecting protein production, diagnosis requires specific blood testing to measure the levels of complement proteins in the blood. Symptoms may include increased susceptibility to infections and autoimmune complications, but definitive diagnosis relies on laboratory confirmation of low C4 levels.
Understanding Your Results
Low C4c levels can indicate Complement Component 4 Deficiency, but results should always be interpreted by a healthcare provider who can consider your clinical history, symptoms, and other relevant factors. Additional testing may be recommended to rule out other conditions that can affect complement levels.
Important Considerations
The information here is for educational purposes only and is not a substitute for professional medical advice. Always consult with a healthcare provider for diagnosis and treatment of immune system disorders.
