Understanding Lab Tests for Bullous Pemphigoid
Written by Private MD Labs Medical Writing Team • Last Updated: September 8, 2025
Bullous pemphigoid is a chronic autoimmune blistering disease that primarily affects older adults. It occurs when the immune system mistakenly produces antibodies that attack proteins in the skin, leading to the formation of large, fluid-filled blisters. Accurate diagnosis requires specialized blood testing to detect these specific autoimmune antibodies.
Recommended Test
Bullous Pemphigoid BP230 Antibody
This test detects BP230 antibodies in the blood, which are produced by the immune system in bullous pemphigoid. These antibodies specifically target the BP230 protein in the skin's basement membrane, causing the separation and blistering characteristic of this autoimmune condition. A positive result strongly supports the diagnosis of bullous pemphigoid.
2907 reviews
Diagnosing Bullous Pemphigoid
While the characteristic blistering pattern can suggest bullous pemphigoid, definitive diagnosis relies on detecting specific antibodies in the blood. The presence of BP230 antibodies is strongly associated with this condition and serves as a key diagnostic marker for confirming the autoimmune nature of the disease.
Understanding Your Results
The BP230 antibody test helps confirm the autoimmune basis of bullous pemphigoid. Positive results indicate the presence of antibodies attacking skin proteins, which correlates with disease activity. This testing is essential for distinguishing bullous pemphigoid from other blistering conditions and guiding appropriate immunosuppressive treatment.
Important Considerations
The information here is for educational purposes only and is not a substitute for professional medical advice. Always consult with a healthcare provider for diagnosis and treatment.
