Sample results
Blood typing inconsistency occurs when initial blood type results do not match expected patterns or when repeat testing shows conflicting results. It is caused by irregular antibodies, rare antigens, recent transfusions, or autoimmune conditions that interfere with standard typing methods. The Antibody Screen with Reflex to Identification, Titer, and Antigen Typing is the most important test for resolving blood typing discrepancies and preventing transfusion reactions.
Blood typing inconsistency is caused by irregular antibodies that develop after blood transfusions or pregnancy, rare blood antigens like Rh variants or weak D expression, autoimmune conditions that produce antibodies against your own red blood cells, or recent transfusions that mix donor cells with your own. Technical factors such as sample contamination, improper storage, or laboratory errors can also create false inconsistencies. Additionally, certain diseases like leukemia or lymphoma can alter red blood cell surface antigens, leading to unexpected typing results.
The Antibody Screen, RBC with Reflex to Identification, Titer, and Antigen Typing is the most important test for blood typing inconsistency because it detects irregular antibodies that interfere with standard blood typing and automatically identifies the specific antibodies present. This comprehensive test measures antibody strength through titer levels and performs detailed antigen typing to identify which specific red blood cell surface markers are causing the discrepancy. The reflex testing approach means if antibodies are detected in the initial screen, the laboratory automatically proceeds to identification and characterization without requiring a second blood draw, providing complete information needed to resolve typing conflicts and ensure safe transfusions.
You should get tested if your blood type results differ from previous records, if you have a history of transfusion reactions or complications during pregnancy, if you are preparing for surgery and your blood bank reports typing difficulties, if you have received multiple blood transfusions or are scheduled for frequent transfusions, or if your healthcare provider reports unexpected antibody findings during routine pre-surgical screening. Testing is also essential if you have been diagnosed with an autoimmune disorder that might affect blood cells or if you are experiencing unexplained symptoms after receiving blood products.
What this means
Your antibody screen came back negative, meaning no unexpected antibodies were detected in your blood. This is the expected and healthy result, indicating that you have a lower risk of complications during pregnancy or blood transfusions.
Recommended actions
If pregnant, follow your healthcare provider's recommendations for repeat testing around 28 weeks
Keep a record of your blood type and antibody status for future medical procedures
If Rh-negative and pregnant, discuss Rh immunoglobulin (RhoGAM) with your doctor
Retest if you have another pregnancy or before any planned surgery requiring transfusions
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Sample results
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