Sample results
Behcet's Disease is a rare chronic inflammatory disorder that causes blood vessel inflammation throughout the body. It is caused by an autoimmune response where the immune system mistakenly attacks blood vessels, with genetic susceptibility linked to the HLA-B51 biomarker. The Cardiolipin Antibodies (IgA, IgG, IgM) test is the most important test for assessing vascular involvement and disease activity in Behcet's Disease.
Behcet's Disease is caused by an autoimmune response where your immune system mistakenly attacks and inflames blood vessels throughout your body. While the exact trigger remains unclear, the condition has a strong genetic component, particularly in people who carry the HLA-B51 or HLA-B5 genetic marker. Environmental factors like viral or bacterial infections may also trigger the disease in people who are genetically predisposed.
The Cardiolipin Antibodies (IgA, IgG, IgM) test is the most important blood test for Behcet's Disease because it detects antibodies associated with vascular involvement and helps assess disease activity. The HLA-A, B, C, DRB1 and DQ High Resolution genetic test is also essential as it identifies the HLA-B51 marker, which indicates increased genetic susceptibility to the condition. Additional tests like Interleukin 17 Serum can measure inflammatory activity, while ASCA antibody tests help identify intestinal involvement. These tests work together to provide a comprehensive picture of disease activity and complications.
You should get tested if you experience recurring mouth sores combined with other symptoms like genital ulcers, eye inflammation, or unusual skin rashes. Testing is also important if you have a family history of Behcet's Disease or are of Mediterranean, Middle Eastern, or East Asian descent and develop unexplained inflammatory symptoms. If you notice painful sores that keep coming back, vision problems, joint pain, or blood clots without obvious cause, these could be warning signs that warrant testing.
What this means
Your cardiolipin IgG antibody level is elevated above the normal threshold. This result suggests your immune system is producing antibodies that may increase your risk for blood clots and could indicate antiphospholipid syndrome, especially if you have a history of clotting or pregnancy complications. A confirmatory retest in 12 weeks is recommended to determine if this elevation is persistent.
Recommended actions
Discuss with your doctor about blood-thinning medications if you have a history of clots or pregnancy loss
Stay well-hydrated and avoid prolonged periods of sitting or immobility
Inform all healthcare providers about this result before surgeries or long flights
Schedule confirmatory retesting in 12 weeks to assess persistence of elevated antibodies
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Sample results
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