Understanding Lab Tests for Bartter Syndrome
Written by Private MD Labs Medical Writing Team • Last Updated: September 8, 2025
Bartter syndrome is a rare inherited kidney disorder that affects the kidneys' ability to reabsorb salt, leading to characteristic electrolyte imbalances including low potassium levels and elevated hormone levels. Specialized blood tests are essential for diagnosing this condition.
Recommended Test
Aldosterone/Plasma Renin Activity Ratio, LC/MS/MS
This comprehensive test measures both aldosterone levels and plasma renin activity, providing crucial information for diagnosing Bartter syndrome. The condition typically causes elevated renin and aldosterone levels due to the kidney's impaired salt reabsorption, making this test a key diagnostic tool for identifying the characteristic hormone pattern associated with this rare inherited kidney defect.
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Diagnosing Bartter Syndrome
Because Bartter syndrome presents with symptoms that can overlap with other electrolyte disorders, accurate diagnosis requires specific laboratory testing. The condition is characterized by a distinctive pattern of hormone levels that can be detected through blood tests, particularly elevated renin and aldosterone levels despite normal blood pressure.
Understanding the Test Results
In Bartter syndrome, patients typically show high plasma renin activity and elevated aldosterone levels, along with low potassium levels. This hormone pattern, combined with clinical symptoms and family history, helps healthcare providers make an accurate diagnosis and develop an appropriate treatment plan.
Important Considerations
The information here is for educational purposes only and is not a substitute for professional medical advice. Always consult with a healthcare provider for diagnosis and treatment. Given the complexity of Bartter syndrome, additional testing and genetic counseling may be recommended.
