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Celiac disease screening test for people with unexplained digestive issues and nutrient deficiencies

Blood Test for Gluten Intolerance and Celiac Disease

Tissue Transglutaminase (tTG) Antibody (IgA)

Google
3,138 reviews
  • Pinpoint gluten intolerance issues accurately
  • Reveal hidden causes of digestive discomfort
  • Clarify unexplained fatigue and nutrient absorption problems
First results as soon as overnight*

90 day happiness guarantee

We stand behind our service

Prescription & fees included

Go directly to the lab, no extra fees

Easy to understand results

With friendly doctor's notes & guidance

Fast & convenient

Lab visit as quick as 10 mins in & out

90 day happiness guarantee

We stand behind our service

Prescription & fees included

Go directly to the lab, no extra fees

Easy to understand results

With friendly doctor's notes & guidance

Fast & convenient

Lab visit as quick as 10 mins in & out

What's this test for?

This test is ideal if you're experiencing unexplained digestive problems like bloating, diarrhea, stomach pain, or constipation. It helps identify Celiac disease and gluten sensitivity that may be causing fatigue, nutrient deficiencies, skin rashes, or unexplained weight loss. Many people use this test when they suspect gluten is affecting their health but want concrete confirmation before making major dietary changes.

How should I prepare for this test?

No fasting is needed for this test, so you can eat and drink normally beforehand. However, it's important that you continue eating gluten-containing foods before testing - if you've already eliminated gluten from your diet, the test may not be accurate. If you're already gluten-free, talk to your doctor about doing a gluten challenge before testing to ensure reliable results.

What's included in this test?

Tissue Transglutaminase (tTG) Antibody (IgA)

This test measures Tissue Transglutaminase (tTG) IgA antibodies, which are proteins your immune system produces when it reacts to gluten. Elevated levels strongly indicate Celiac disease, an autoimmune condition where gluten damages the small intestine and prevents proper nutrient absorption. This test is highly accurate for detecting gluten-sensitive enteropathies and the related skin condition dermatitis herpetiformis.

What happens after I get my results?
You'll receive detailed doctor notes in simple language explaining what your tTG antibody levels mean for your digestive health and gluten tolerance. These notes include personalized recommendations like whether you should eliminate gluten from your diet, what follow-up tests might be needed, or when to consult a gastroenterologist. You'll also get the standard lab report and can track your antibody levels over time using our trends feature, which is especially helpful if you're implementing a gluten-free diet and want to monitor improvement.
Who should consider getting this test?
This test is recommended for anyone experiencing chronic digestive issues, unexplained fatigue, anemia, or skin rashes that might be gluten-related. It's especially important if you have a family history of Celiac disease, Type 1 diabetes, or other autoimmune conditions. Children with growth delays or failure to thrive should also be tested, as Celiac disease can interfere with nutrient absorption during critical developmental years.
What symptoms indicate I may need this test?
Common symptoms include chronic diarrhea or constipation, bloating, gas, abdominal pain, and unexplained weight loss. You might also experience fatigue, brain fog, headaches, joint pain, numbness or tingling, or a blistery skin rash called dermatitis herpetiformis. Some people have iron deficiency anemia or vitamin deficiencies despite eating a healthy diet, which can indicate poor nutrient absorption from undiagnosed Celiac disease.
How can I naturally support my digestive health with gluten sensitivity?
If you test positive, following a strict gluten-free diet is essential to allow your intestines to heal and prevent further damage. Focus on naturally gluten-free whole foods like fruits, vegetables, lean proteins, rice, quinoa, and potatoes. Take a high-quality multivitamin to address nutrient deficiencies common in Celiac disease, particularly iron, B vitamins, vitamin D, and calcium. Work with a dietitian who specializes in Celiac disease to ensure you're meeting all nutritional needs while avoiding hidden sources of gluten.
What is Celiac disease and why does it matter?
Celiac disease is an autoimmune disorder where eating gluten triggers your immune system to attack the lining of your small intestine. This damage prevents proper absorption of nutrients from food, leading to deficiencies, fatigue, and various health problems. Left untreated, Celiac disease can cause serious complications including osteoporosis, infertility, neurological problems, and an increased risk of certain cancers, which is why early diagnosis and treatment are so important.
What does a positive tTG antibody result mean?
A positive result means elevated levels of tTG IgA antibodies were detected, which strongly suggests Celiac disease or gluten sensitivity. This indicates your immune system is reacting to gluten and likely causing damage to your small intestine. Your doctor will typically recommend a follow-up endoscopy with intestinal biopsy to confirm the diagnosis before starting treatment, as this is considered the gold standard for diagnosing Celiac disease.
How often should I retest my tTG antibody levels?
After being diagnosed with Celiac disease and starting a gluten-free diet, retesting every 6-12 months helps confirm your antibody levels are decreasing and your intestines are healing. Once your levels normalize and remain stable, annual testing is typically sufficient to ensure you're maintaining a truly gluten-free diet. If you accidentally consume gluten or experience returning symptoms, your doctor may recommend retesting sooner to check if antibody levels have risen again.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at [email protected], and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at [email protected]. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email [email protected].
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email [email protected].

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

You get clinical lab reports & simplified health insights.
Save time & gas, go straight to the lab. Our doctors cover the rest.
Results start landing the next day after your lab visit.*
We don’t sell or share your data. Your time & privacy matter.
US-licensed doctors have your back if things get unclear.
No hidden fees, nice discounts for regular checkups.
Save a trip to the doctor, go directly to the lab
Instant orders, results often overnight*
Results explained in simple language
Reviewed by US licensed doctors
Fast & confidential, we never sell or share your data
No insurance needed, transparent pricing
Demo results
Tissue Transglutaminase (tTG) IgA Antibody 42 U/mL
Demo results
Negative < 20 Positive ≥ 20
42 U/mL

What this means

Your tTG IgA antibody level is elevated, which strongly suggests your immune system is reacting to gluten. This result indicates possible Celiac disease or gluten-sensitive enteropathy that may be causing your digestive symptoms, fatigue, or nutrient absorption issues. A follow-up consultation with a gastroenterologist and possible intestinal biopsy is recommended to confirm the diagnosis.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More complex tests, such as hormone panels, may take up to 10–15 business days due to their complexity.
Here’s how easy it is to get blood work done on your terms
Choose a checkup
Order your test Save a trip to the doctor. Your results will come with clear, friendly explanations. Takes 2 minutes
Book a lab
Book an appointment Visit any of our 4,000 nearby lab locations to have your samples collected. Book or walk-in
Choose a checkup
Get results Receive a clear, easy-to-digest health report by email & SMS within a few business days. Get answers, fast

Blood Test for Gluten Intolerance and Celiac Disease

Google
3,138 reviews
  • Pinpoint gluten intolerance issues accurately
  • Reveal hidden causes of digestive discomfort
  • Clarify unexplained fatigue and nutrient absorption problems

1,000,000+ blood tests later, here's what our customers say

Google reviews 3138 reviews Next
Still got questions? Text our super-cool support team at 754-799-7833 to get help finding your ideal checkup.