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Thyroid antibody test for autoimmune disorders causing fatigue, weight changes, and thyroid dysfunction

Thyroid Antibody Test for Fatigue and Weight Changes

Thyroid Peroxidase (TPO) and Thyroglobulin Antibodies (TAA)

Google
3,138 reviews
  • Pinpoint the cause of your fatigue
  • Reveal hidden thyroid issues effortlessly
  • Clarify the reason behind weight changes
First results as soon as overnight*

90 day happiness guarantee

We stand behind our service

Prescription & fees included

Go directly to the lab, no extra fees

Easy to understand results

With friendly doctor's notes & guidance

Fast & convenient

Lab visit as quick as 10 mins in & out

90 day happiness guarantee

We stand behind our service

Prescription & fees included

Go directly to the lab, no extra fees

Easy to understand results

With friendly doctor's notes & guidance

Fast & convenient

Lab visit as quick as 10 mins in & out

What's this test for?

This test is ideal if you're experiencing unexplained fatigue, weight changes, mood swings, or temperature sensitivity that might be related to thyroid problems. It helps identify autoimmune thyroid conditions like Hashimoto's disease or Graves disease, where your immune system mistakenly attacks your thyroid gland. Many people use this test when they have thyroid symptoms or abnormal thyroid function tests and want to understand if autoimmune issues are the underlying cause.

What's included in this test?

Thyroglobulin Antibodies Thyroid Peroxidase Antibodies

This test measures two important thyroid antibodies that indicate autoimmune thyroid disease. Thyroid Peroxidase Antibodies (TPO) help diagnose Hashimoto's thyroiditis, the most common cause of hypothyroidism, while Thyroglobulin Antibodies (TAA) provide additional confirmation of autoimmune activity. Together, these markers help distinguish autoimmune thyroid conditions from other causes of thyroid dysfunction.

What happens after I get my results?

You'll receive detailed doctor notes in simple language explaining what your thyroid antibody levels mean and how they relate to autoimmune thyroid conditions. These notes include personalized recommendations like dietary changes, supplements that may support thyroid health, or whether you should follow up with an endocrinologist. Along with your standard lab report, you can use our trends feature to track your antibody levels over time, which is especially helpful for monitoring disease progression or treatment effectiveness.

Who should consider getting this test?
This test is important for anyone experiencing thyroid symptoms like fatigue, weight changes, or mood issues, especially if routine thyroid tests show abnormal results. It's also recommended for people with a family history of autoimmune thyroid disease, women who are pregnant or planning pregnancy, and anyone diagnosed with other autoimmune conditions who may be at higher risk for thyroid problems.
What symptoms indicate I may need this test?
Common symptoms include persistent fatigue, unexplained weight gain or difficulty losing weight, feeling unusually cold or sensitive to temperature, hair thinning or loss, dry skin, and mood changes like depression or anxiety. You might also experience muscle weakness, joint pain, irregular menstrual periods, brain fog, or an enlarged thyroid gland (goiter). If you have these symptoms along with abnormal TSH or thyroid hormone levels, this test can help identify if autoimmune disease is the cause.
How can I naturally support my thyroid health with autoimmune thyroid disease?
Managing autoimmune thyroid conditions often involves reducing inflammation through diet, such as limiting gluten and processed foods while focusing on anti-inflammatory foods like fatty fish, leafy greens, and berries. Ensuring adequate selenium intake through Brazil nuts, eggs, and seafood may help reduce thyroid antibody levels. Managing stress through yoga, meditation, or gentle exercise, getting 7-8 hours of quality sleep, and avoiding environmental toxins can also support thyroid function and reduce autoimmune activity.
What are thyroid antibodies and why do they matter?
Thyroid antibodies are proteins your immune system creates when it mistakenly identifies your thyroid tissue as a threat. When present in high levels, these antibodies attack and damage the thyroid gland, leading to conditions like Hashimoto's disease (causing hypothyroidism) or Graves disease (causing hyperthyroidism). Detecting these antibodies helps explain why your thyroid isn't functioning properly and guides appropriate treatment and monitoring strategies.
What does it mean if my thyroid antibodies are high?
High thyroid antibody levels indicate that your immune system is actively attacking your thyroid gland, which is a hallmark of autoimmune thyroid disease. Elevated TPO antibodies are most commonly associated with Hashimoto's thyroiditis, while elevated thyroglobulin antibodies provide additional confirmation of autoimmune activity. High antibodies often mean you'll need closer monitoring of your thyroid function and may eventually require thyroid hormone replacement therapy.
What causes thyroid antibodies to develop?
Thyroid antibodies develop due to a combination of genetic predisposition and environmental triggers that cause your immune system to malfunction. Factors that may trigger or worsen autoimmune thyroid disease include chronic stress, viral infections, hormonal changes (especially during pregnancy or menopause), nutrient deficiencies like selenium or vitamin D, excessive iodine intake, and environmental toxins. Having other autoimmune conditions or a family history also increases your risk.
How often should I retest my thyroid antibodies?
If you're newly diagnosed with autoimmune thyroid disease, your doctor may retest antibodies every 6-12 months to monitor disease progression and adjust treatment as needed. Once your condition is stable and you're on appropriate treatment, annual testing is typically sufficient. However, if you experience new or worsening symptoms, more frequent testing may be needed to assess disease activity and ensure your thyroid hormone levels remain balanced.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at [email protected], and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at [email protected]. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email [email protected].
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email [email protected].

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

You get clinical lab reports & simplified health insights.
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Results start landing the next day after your lab visit.*
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Instant orders, results often overnight*
Results explained in simple language
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Demo results
Thyroid Peroxidase Antibodies (TPO) 68 IU/mL
Demo results
Low Optimal 0 - 34 High
68 IU/mL

What this means

Your TPO antibodies are elevated above the normal range, indicating that your immune system is producing antibodies against your thyroid gland. This is a strong indicator of autoimmune thyroid disease, most commonly Hashimoto's thyroiditis, which can lead to thyroid dysfunction over time and explain symptoms like fatigue, weight changes, or mood issues.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More complex tests, such as hormone panels, may take up to 10–15 business days due to their complexity.
Here’s how easy it is to get blood work done on your terms
Choose a checkup
Order your test Save a trip to the doctor. Your results will come with clear, friendly explanations. Takes 2 minutes
Book a lab
Book an appointment Visit any of our 4,000 nearby lab locations to have your samples collected. Book or walk-in
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Get results Receive a clear, easy-to-digest health report by email & SMS within a few business days. Get answers, fast

Thyroid Antibody Test for Fatigue and Weight Changes

Google
3,138 reviews
  • Pinpoint the cause of your fatigue
  • Reveal hidden thyroid issues effortlessly
  • Clarify the reason behind weight changes

1,000,000+ blood tests later, here's what our customers say

Google reviews 3138 reviews Next
Still got questions? Text our super-cool support team at 754-799-7833 to get help finding your ideal checkup.