TBG (Thyroxine Binding Globulin)
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Thyroid Test for Weight Changes and Energy Problems
TBG (Thyroxine Binding Globulin)
- Reveal thyroid imbalances affecting your energy
- Clarify unexplained weight changes effortlessly
- Pinpoint hormone issues impacting your mood
$601
Example results
First results as soon as overnight*
90 day happiness guarantee
We stand behind our service
Prescription & fees included
Go directly to the lab, no extra fees
Easy to understand results
With friendly doctor's notes & guidance
Fast & convenient
Lab visit as quick as 10 mins in & out
90 day happiness guarantee
We stand behind our service
Prescription & fees included
Go directly to the lab, no extra fees
Easy to understand results
With friendly doctor's notes & guidance
Fast & convenient
Lab visit as quick as 10 mins in & out
What's this test for?
This test is ideal if you're experiencing unexplained fatigue, weight changes, mood swings, or temperature sensitivity that might be related to thyroid issues. It helps identify whether your thyroid hormones are being transported properly through your bloodstream, which can affect your energy levels, metabolism, and overall well-being. Many people use this test when standard thyroid tests seem normal but symptoms persist, or to clarify conflicting thyroid results.
How should I prepare for this test?
No special preparation is needed for this test—no fasting is required. You can take the test at any time of day and continue your normal eating and drinking habits beforehand. However, it's helpful to inform your healthcare provider about any medications you're taking, especially birth control pills or hormone therapy, as these can affect TBG levels and should be noted when interpreting your results.
What's included in this test?
This test evaluates the level of Thyroxine Binding Globulin (TBG) in your blood, which is the primary protein that transports thyroid hormones throughout your body. Understanding your TBG levels helps clarify whether abnormal thyroid hormone levels are due to actual thyroid dysfunction or simply variations in the binding protein. This is particularly important when other thyroid tests show confusing results or when you're taking medications like birth control or hormone replacement therapy that can affect TBG levels.
What happens after I get my results?
You'll receive detailed doctor notes in simple language explaining what your TBG levels mean for your thyroid function and how it relates to symptoms like fatigue or weight changes. These notes include personalized recommendations like dietary adjustments, supplement suggestions, or whether you should follow up with an endocrinologist for further thyroid evaluation. Along with your standard lab report, you can use our trends feature to monitor your TBG levels over time, especially helpful if you're managing thyroid conditions or making lifestyle adjustments.
Who should consider getting this test?
This test is particularly valuable if your standard thyroid tests (like TSH or Free T4) show abnormal results but don't match your symptoms, or if results vary significantly between tests. It's also important for people taking estrogen-containing medications like birth control pills or hormone replacement therapy, pregnant women with thyroid concerns, and anyone with a family history of thyroid disorders who wants a more complete picture of their thyroid function.
What symptoms indicate I may need this test?
You might benefit from this test if you're experiencing classic thyroid symptoms like persistent fatigue, unexplained weight gain or loss, feeling unusually cold or hot, mood changes, or difficulty concentrating, especially if your standard thyroid tests don't fully explain these symptoms. It's also worth considering if you're on hormonal medications and notice your energy or metabolism has changed, or if you have inconsistent thyroid test results that are hard to interpret.
How can I naturally support healthy thyroid hormone transport?
Supporting your body's ability to transport thyroid hormones starts with maintaining overall liver health, as the liver produces TBG. Eating a balanced diet rich in protein, avoiding excessive alcohol, and ensuring adequate intake of B vitamins and antioxidants can help. Managing stress through regular exercise, adequate sleep, and relaxation techniques also supports healthy hormone balance and transport throughout your body.
What is TBG and why does it matter?
Thyroxine Binding Globulin (TBG) is a protein made by your liver that acts as a carrier for thyroid hormones in your bloodstream. Think of it as a delivery truck that transports thyroid hormones to where they're needed throughout your body. The amount of TBG you have can affect how much thyroid hormone is available to your cells, which is why measuring it helps doctors understand whether thyroid test results reflect actual thyroid problems or just variations in the carrier protein.
What does high TBG mean?
High TBG levels mean you have more carrier protein in your blood, which can happen during pregnancy, when taking estrogen-containing medications like birth control pills, or due to certain genetic factors. When TBG is high, your total thyroid hormone levels may appear elevated even though the active hormone available to your cells is normal. This is why your doctor might order this test to clarify whether your thyroid is truly overactive or if it's just a binding protein variation.
What does low TBG mean?
Low TBG levels mean you have less carrier protein available to transport thyroid hormones, which can occur with certain medications like steroids or testosterone, liver or kidney disease, malnutrition, or genetic factors. When TBG is low, your total thyroid hormone levels may appear decreased even though your thyroid is functioning normally. Understanding this helps prevent unnecessary thyroid treatment and clarifies whether symptoms are truly thyroid-related or due to other factors.
How’s this work?
Long story short:
- In the test options, use the filters or search box to narrow your choices and find the test you want.
- If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
- Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
- If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
- When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
- Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
- You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy! If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
How do I know which test to get?
Just text or call us at 754-799-7833, email us at [email protected], and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Just reach out to us via text at 754-799-7833 or shoot us an email at [email protected]. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.
There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.
Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.
This policy applies to all insurance companies, including federal health insurance programs like Medicare.
If you have any questions, please text us at 754-799-7833 or email [email protected].
Can I cancel my order?
We get it – sometimes your needs change.
As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.
If you have any further questions, please text us at 754-799-7833 or email [email protected].
You can read more about our cancellation policy here.
How can I find a lab location near me?
Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.
If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
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Demo results
TBG (Thyroxine Binding Globulin)
32 µg/mL
Demo results
Low
Optimal 13 - 30
High
32 µg/mL
What this means
Your TBG level is elevated above the optimal range, which means you have more carrier protein for thyroid hormones than usual. This can happen with estrogen-containing medications, pregnancy, or certain genetic factors, and may cause your total thyroid hormone tests to appear high even when your active thyroid function is normal.
Recommended actions
Discuss any hormonal medications with your doctor, as birth control or hormone therapy can elevate TBG
Support liver health with a balanced diet rich in leafy greens, lean protein, and antioxidants
Avoid excessive alcohol consumption which can affect liver function and protein production
Retest in 8-12 weeks, especially if starting or stopping hormonal medications
* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More complex tests, such as hormone panels, may take up to 10–15 business days due to their complexity.
Here’s how easy it is to get blood work done on your terms
Order your test
Save a trip to the doctor. Your results will come with clear, friendly explanations.
Takes 2 minutes
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Visit any of our 4,000 nearby lab locations to have your samples collected.
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Get results
Receive a clear, easy-to-digest health report by email & SMS within a few business days.
Get answers, fast
Thyroid Test for Weight Changes and Energy Problems
- Reveal thyroid imbalances affecting your energy
- Clarify unexplained weight changes effortlessly
- Pinpoint hormone issues impacting your mood
$601
Example results
1,000,000+ blood tests later, here's what our customers say
3138 reviews
Still got questions?
Text our super-cool support team at 754-799-7833 to get help finding your ideal checkup.
