What's this test for?

This test is ideal if you're experiencing unexplained chronic fatigue, persistent muscle pain, or symptoms of liver problems like jaundice or abdominal discomfort. It helps identify autoimmune hepatitis and other autoimmune conditions where your immune system mistakenly attacks smooth muscle tissue in your liver and other organs. Many people use this test when standard liver tests show abnormalities but the cause is unclear.

What happens after I get my results?

You'll receive detailed doctor notes in simple language explaining what your smooth muscle antibody levels mean for your liver health and immune function. These notes include personalized recommendations like whether you should follow up with a gastroenterologist or hepatologist, lifestyle considerations, and what additional tests might be helpful. You'll also get the standard lab report and can track your antibody levels over time using our trends feature, which is especially useful if you're monitoring a known autoimmune condition.

What's included in this test?

This test measures smooth muscle antibodies in your blood. These antibodies are immune proteins that attack smooth muscle tissue and are found in 85% of people with chronic active hepatitis. They help doctors distinguish autoimmune liver disease from other types of liver problems like viral hepatitis, drug-induced liver damage, or bile duct obstruction. The reflex to titer means if antibodies are detected, the lab will automatically measure the concentration level to help assess severity.

How should I prepare for this test?

No special preparation is typically required for this test. You can eat and drink normally before your blood draw, and you don't need to fast. Continue taking your regular medications unless your healthcare provider instructs otherwise. Simply arrive at the lab during their business hours for your blood sample collection.

When will I get my results?

Most results are available within 3-5 business days after your blood sample is collected. If the initial screening detects smooth muscle antibodies, the reflex titer test is performed automatically, which may add an additional 1-2 days to the turnaround time. You'll receive an email notification when your results are ready to view securely online.

Who should consider getting this test?

This test is particularly important for people with elevated liver enzymes on routine blood work without an obvious cause, those experiencing symptoms of autoimmune hepatitis like fatigue and jaundice, or anyone with unexplained chronic muscle pain. It's also useful if you have other autoimmune conditions or a family history of autoimmune disease, as these conditions can cluster together.

What symptoms indicate I may need this test?

Common symptoms that warrant this test include persistent fatigue that doesn't improve with rest, unexplained muscle aches and weakness, yellowing of the skin or eyes, dark urine, or discomfort in the upper right abdomen. You might also experience loss of appetite, nausea, or itchy skin. Some people have no symptoms at all and discover liver abnormalities through routine blood work.

What does a positive smooth muscle antibody result mean?

A positive result means your immune system is producing antibodies against smooth muscle tissue, which strongly suggests autoimmune hepatitis, especially if found at higher concentrations. However, positive results can occasionally occur in other conditions like primary biliary cirrhosis, certain viral infections, or even in some healthy individuals at low levels. Your doctor will interpret the results alongside your symptoms, medical history, and other liver tests.

What causes smooth muscle antibodies to develop?

Smooth muscle antibodies develop when the immune system mistakenly identifies smooth muscle proteins as foreign invaders and creates antibodies against them. The exact trigger for this autoimmune response isn't fully understood, but it may involve genetic predisposition combined with environmental factors like viral infections or medication reactions. In autoimmune hepatitis, this immune response specifically targets liver cells, causing chronic inflammation.

How often should I retest my smooth muscle antibodies?

If you've been diagnosed with autoimmune hepatitis, your doctor will typically monitor your antibody levels every 3-6 months during initial treatment to assess response to therapy. Once your condition is stable, testing may be reduced to once or twice yearly. If your initial test was negative but liver problems persist, your doctor may retest in several months as antibody levels can fluctuate.

Getting your blood test with us is easy, private & backed by the power of science.Long story short: In the test options, use the filters or search box to narrow your choices and find the test you want. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy! If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

How do I know which test to get?

In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option. Just text or call us at 754-799-7833, email us at support@privatemdlabs.com, and we'll gladly help you. We've got your back and reply quickly.

When will my lab results be available?

Most test results will be available within 1–3 business days. Once they're ready, we'll send an email and text message to let you know. After your blood draw, just hang tight and don't worry – we'll keep you updated and in the loop! If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com, and we'll gladly help you.

Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?

Absolutely! We totally understand that errors can happen. No worries, we're here to help you. Just reach out to us via text at 754-799-7833 or shoot us an email at support@privatemdlabs.com. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you. There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out. Our lab requires an address to be listed to generate an order.

Do you accept health insurance?

Only HSA & FSA is accepted. Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts. This policy applies to all insurance companies, including federal health insurance programs like Medicare. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com.

Can I cancel my order?

Yes. We get it – sometimes your needs change. As long as your samples haven’t been collected yet, we’re happy to help you cancel your order. If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com. You can read more about our cancellation policy here.

How can I find a lab location near me?

During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp). Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

Liver Antibody Test - Autoimmune Hepatitis Check

Getting your blood test with us is easy, private & backed by the power of science.

Long story short:

In the test options, use the filters or search box to narrow your choices and find the test you want.
If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!

754-799-7833

[email protected]

Blood Test for Liver Problems and Chronic Fatigue

Smooth Muscle Antibody with Reflex to Titer

90 day happiness guarantee

Prescription & fees included

Easy to understand results

Fast & convenient

90 day happiness guarantee

Prescription & fees included

Easy to understand results

Fast & convenient

What's this test for?

How should I prepare for this test?

What's included in this test?

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

Blood Test for Liver Problems and Chronic Fatigue

90 day happiness guarantee

Prescription & fees included

Easy to understand results

Fast & convenient

1,000,000+ blood tests later, here's what our customers say