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SHBG test for men and women experiencing hormonal imbalance, low energy, and weight changes

SHBG Test for Hormone Imbalance and Low Energy

Sex Hormone Binding Globulin, SHBG

Google
3,138 reviews
  • Pinpoint the cause of hormonal imbalances
  • Reveal factors affecting your energy levels
  • Clarify reasons behind unexpected weight changes
First results as soon as overnight*

90 day happiness guarantee

We stand behind our service

Prescription & fees included

Go directly to the lab, no extra fees

Easy to understand results

With friendly doctor's notes & guidance

Fast & convenient

Lab visit as quick as 10 mins in & out

90 day happiness guarantee

We stand behind our service

Prescription & fees included

Go directly to the lab, no extra fees

Easy to understand results

With friendly doctor's notes & guidance

Fast & convenient

Lab visit as quick as 10 mins in & out

What's this test for?

This test is ideal if you're experiencing unexplained fatigue, difficulty building muscle, unexpected weight changes, low sex drive, or irregular periods. SHBG acts like a hormone traffic controller, managing how much testosterone and estrogen is available for your body to use. Many people use this test when they suspect hormonal imbalance but want to understand the root cause affecting their energy, metabolism, and overall vitality.

How should I prepare for this test?

No biotin: 72 hours

If you're taking high-dose biotin supplements (also called vitamin B7, B8, vitamin H, or coenzyme R), you should stop taking them at least 72 hours before your blood draw. Biotin can interfere with certain lab tests and affect the accuracy of your results. Otherwise, no special preparation is typically needed for this test.

What's included in this test?

Sex Hormone Binding Globulin

This test measures Sex Hormone Binding Globulin (SHBG), a protein that binds to sex hormones like testosterone and estrogen in your bloodstream. SHBG levels determine how much of these hormones are available for your body to actually use, which directly impacts your energy, muscle mass, fat distribution, libido, and overall vitality. Understanding your SHBG helps explain why total hormone levels might look normal but you still experience symptoms of hormonal imbalance.

What happens after I get my results?
You'll receive detailed doctor notes in simple language explaining what your SHBG levels mean for your hormone balance, energy, and metabolism. These notes include personalized recommendations like dietary changes, exercise adjustments, supplement suggestions, or whether you should investigate further hormone testing. You'll also get the standard lab report and can track your SHBG levels over time using our trends feature to see how lifestyle changes or treatments are affecting your hormone availability.
Who should consider getting this test?
This test is valuable for anyone experiencing symptoms of hormonal imbalance despite normal testosterone or estrogen levels. It's especially useful for men with low energy or difficulty building muscle, women with irregular periods or fertility concerns, athletes monitoring performance and recovery, and anyone struggling with unexplained weight changes or decreased libido. People on hormone therapy or testosterone replacement may also use this test to optimize their treatment.
What symptoms indicate I may need this test?
Common symptoms include persistent fatigue even with adequate sleep, difficulty gaining or maintaining muscle mass, unexplained weight gain especially around the midsection, low or decreased sex drive, irregular menstrual cycles in women, erectile dysfunction in men, mood changes, and brain fog. You might also consider this test if your total testosterone or estrogen levels appear normal but you still experience these hormonal symptoms.
How can I naturally support healthy SHBG levels?
Maintaining a healthy weight through balanced nutrition and regular exercise can help optimize SHBG levels. Eating adequate protein, including fiber-rich foods, and reducing refined carbohydrates and sugar can make a difference. Regular strength training and moderate cardio exercise support healthy hormone balance. Getting 7-9 hours of quality sleep, managing stress, limiting alcohol consumption, and avoiding endocrine-disrupting chemicals in plastics and personal care products can also help.
What is SHBG and why does it matter?
SHBG (Sex Hormone Binding Globulin) is a protein made by your liver that binds to sex hormones like testosterone and estrogen as they travel through your bloodstream. Think of it as a carrier that holds onto hormones, making them temporarily unavailable for your body to use. Only unbound or free hormones can enter cells and have effects. When SHBG is too high, it can bind too much hormone and reduce what's available, potentially causing low hormone symptoms even when total levels look normal.
What does high SHBG mean?
High SHBG means more of your sex hormones are bound up and unavailable for your body to use, which can lead to symptoms of low testosterone or estrogen even when total hormone levels appear normal. In men, this might cause fatigue, low libido, and difficulty building muscle. In women, it may contribute to irregular periods or fertility issues. High SHBG can be caused by hyperthyroidism, low protein diets, certain medications, or high estrogen states.
What does low SHBG mean?
Low SHBG means less protein is available to bind hormones, resulting in more free (active) hormones circulating in your body. While this might sound beneficial, it can actually cause problems like acne, oily skin, hair loss, mood swings, and increased risk of metabolic issues. Low SHBG is often associated with insulin resistance, obesity, hypothyroidism, and polycystic ovary syndrome (PCOS). It may also indicate too much available testosterone or estrogen causing unwanted effects.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at [email protected], and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at [email protected]. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email [email protected].
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email [email protected].

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

You get clinical lab reports & simplified health insights.
Save time & gas, go straight to the lab. Our doctors cover the rest.
Results start landing the next day after your lab visit.*
We don’t sell or share your data. Your time & privacy matter.
US-licensed doctors have your back if things get unclear.
No hidden fees, nice discounts for regular checkups.
Save a trip to the doctor, go directly to the lab
Instant orders, results often overnight*
Results explained in simple language
Reviewed by US licensed doctors
Fast & confidential, we never sell or share your data
No insurance needed, transparent pricing
Demo results
Sex Hormone Binding Globulin (SHBG) 68 nmol/L
Demo results
Low Optimal 20 - 60 High
68 nmol/L

What this means

Your SHBG level is elevated, which means more of your sex hormones are bound up and unavailable for your body to use. This can contribute to symptoms like low energy, reduced libido, and difficulty building muscle even when total hormone levels appear normal. High SHBG often responds well to dietary and lifestyle modifications.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More complex tests, such as hormone panels, may take up to 10–15 business days due to their complexity.
Here’s how easy it is to get blood work done on your terms
Choose a checkup
Order your test Save a trip to the doctor. Your results will come with clear, friendly explanations. Takes 2 minutes
Book a lab
Book an appointment Visit any of our 4,000 nearby lab locations to have your samples collected. Book or walk-in
Choose a checkup
Get results Receive a clear, easy-to-digest health report by email & SMS within a few business days. Get answers, fast

SHBG Test for Hormone Imbalance and Low Energy

Google
3,138 reviews
  • Pinpoint the cause of hormonal imbalances
  • Reveal factors affecting your energy levels
  • Clarify reasons behind unexpected weight changes

1,000,000+ blood tests later, here's what our customers say

Google reviews 3138 reviews Next
Still got questions? Text our super-cool support team at 754-799-7833 to get help finding your ideal checkup.