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Protein electrophoresis test for detecting multiple myeloma and unexplained fatigue symptoms

Blood Test for Unexplained Fatigue and Protein Imbalances

Protein Electrophoresis and Kappa/Lambda Light Chains

Google
3,138 reviews
  • Unveil hidden protein imbalances effortlessly
  • Detect early signs of multiple myeloma
  • Clarify unexplained fatigue and weakness
First results as soon as overnight*

90 day happiness guarantee

We stand behind our service

Prescription & fees included

Go directly to the lab, no extra fees

Easy to understand results

With friendly doctor's notes & guidance

Fast & convenient

Lab visit as quick as 10 mins in & out

90 day happiness guarantee

We stand behind our service

Prescription & fees included

Go directly to the lab, no extra fees

Easy to understand results

With friendly doctor's notes & guidance

Fast & convenient

Lab visit as quick as 10 mins in & out

What's this test for?

This test is ideal if you're experiencing unexplained fatigue, persistent weakness, frequent infections, or unexplained bone pain. It helps detect abnormal protein levels in your blood that could indicate multiple myeloma or other protein-related disorders. Many people use this test when standard blood work hasn't explained their symptoms or when doctors suspect a plasma cell disorder.

How should I prepare for this test?

Overnight fasting is preferred for this test to ensure the most accurate results. This means avoiding all food and drinks except water for 8-12 hours before your blood draw. You can take your regular medications with water unless your doctor advises otherwise. Schedule your appointment for the morning if possible to make fasting easier.

What's included in this test?

Abnormal Protein Band 1 Abnormal Protein Band 2 Abnormal Protein Band 3 Albumin Alpha 1 Globulin Alpha 2 Globulin Beta 1 Globulin Beta 2 Globulin Gamma Globulin Kappa Kappa/Lambda Ratio Lambda Protein, Total

This comprehensive panel evaluates your blood protein composition through protein electrophoresis, which separates proteins into six distinct fractions including albumin and various globulins. It measures kappa and lambda light chains along with their ratio, which are crucial markers for detecting plasma cell disorders like multiple myeloma. The test also identifies any abnormal protein bands that shouldn't normally be present, providing a complete picture of protein abnormalities that could explain symptoms like fatigue, weakness, or bone pain.

What happens after I get my results?
You'll receive detailed doctor notes in simple language explaining what your protein patterns and light chain ratios mean for your health. These notes include personalized recommendations such as whether further testing is needed, lifestyle modifications, or if you should consult with a hematologist or oncologist. You'll also get the standard lab report and can track your protein levels over time using our trends feature, which is especially helpful for monitoring changes or treatment effectiveness.
When will I get my results?
Results for this specialized test are typically available within 3-5 business days after your blood sample reaches the laboratory. The test requires careful analysis of protein patterns and light chain measurements, which takes a bit longer than standard blood work. You'll receive an email notification as soon as your results are ready to view in your secure online account.
Who should consider getting this test?
This test is important for anyone experiencing unexplained fatigue, weakness, recurring infections, or bone pain that hasn't been diagnosed. It's especially recommended if you have a family history of multiple myeloma or related blood disorders, or if your doctor has found elevated protein levels or anemia in routine blood work. People over 65 or those with unexplained kidney problems should also consider this screening.
What symptoms indicate I may need this test?
Common symptoms that warrant this test include persistent fatigue that doesn't improve with rest, unexplained weakness, frequent infections, bone pain especially in the back or ribs, and unexplained weight loss. You may also need this test if you've experienced foamy urine indicating excess protein, numbness or tingling in your extremities, or if blood work showed unexplained anemia or high calcium levels.
What is the Kappa/Lambda ratio and why does it matter?
The Kappa/Lambda ratio measures the balance between two types of light chain proteins produced by plasma cells in your immune system. A normal ratio indicates healthy plasma cell function, while an abnormal ratio can be an early sign of multiple myeloma or other plasma cell disorders. This ratio is one of the most sensitive markers for detecting these conditions before they cause serious symptoms.
What does abnormal protein electrophoresis mean?
Abnormal protein electrophoresis means the pattern of proteins in your blood is different from what's expected in healthy individuals. This could show up as an unusual spike called a monoclonal protein or M-protein, which may indicate conditions like multiple myeloma, or it could show changes in albumin or globulin levels suggesting liver disease, kidney problems, or chronic inflammation. Your doctor will interpret these patterns along with your symptoms and other test results to determine what's causing the abnormality.
What happens if my results are abnormal?
If your results show abnormal protein patterns or light chain ratios, your doctor will likely recommend additional testing such as bone marrow biopsy, imaging studies, or urine protein tests to determine the cause. Abnormal results don't automatically mean cancer, as they can also indicate chronic infections, autoimmune conditions, or liver and kidney diseases. Early detection through this test allows for prompt treatment and better outcomes, so follow-up with a hematologist is typically recommended for significantly abnormal results.
How often should I retest my protein levels?
If you have a diagnosed plasma cell disorder or monoclonal gammopathy, your doctor will typically recommend retesting every 3-6 months to monitor for progression or response to treatment. For those with borderline abnormal results or a condition called MGUS (monoclonal gammopathy of undetermined significance), annual testing is common. If your initial results are normal but symptoms persist, your doctor may suggest retesting in 6-12 months.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at [email protected], and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at [email protected]. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email [email protected].
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email [email protected].

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

You get clinical lab reports & simplified health insights.
Save time & gas, go straight to the lab. Our doctors cover the rest.
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Save a trip to the doctor, go directly to the lab
Instant orders, results often overnight*
Results explained in simple language
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Fast & confidential, we never sell or share your data
No insurance needed, transparent pricing
Demo results
Kappa/Lambda Ratio 2.8
Demo results
Low Optimal 0.26 - 1.65 High
2.8

What this means

Your Kappa/Lambda ratio is elevated above the normal range, which indicates an imbalance in the light chain proteins produced by your plasma cells. While this doesn't automatically mean you have multiple myeloma, it warrants further evaluation as it can be an early indicator of plasma cell disorders or monoclonal gammopathies.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More complex tests, such as hormone panels, may take up to 10–15 business days due to their complexity.
Here’s how easy it is to get blood work done on your terms
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Order your test Save a trip to the doctor. Your results will come with clear, friendly explanations. Takes 2 minutes
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Get results Receive a clear, easy-to-digest health report by email & SMS within a few business days. Get answers, fast

Blood Test for Unexplained Fatigue and Protein Imbalances

Google
3,138 reviews
  • Unveil hidden protein imbalances effortlessly
  • Detect early signs of multiple myeloma
  • Clarify unexplained fatigue and weakness

1,000,000+ blood tests later, here's what our customers say

Google reviews 3138 reviews Next
Still got questions? Text our super-cool support team at 754-799-7833 to get help finding your ideal checkup.