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Parietal cell antibody test for identifying autoimmune gastritis and pernicious anemia risk

Blood Test for Fatigue and B12 Deficiency

Parietal Cell Antibody, ELISA

Google
3,138 reviews
  • Detects stomach lining antibodies
  • Checks for stomach tissue attack
  • Identifies possible autoimmune issues
First results as soon as overnight*

90 day happiness guarantee

We stand behind our service

Prescription & fees included

Go directly to the lab, no extra fees

Easy to understand results

With friendly doctor's notes & guidance

Fast & convenient

Lab visit as quick as 10 mins in & out

90 day happiness guarantee

We stand behind our service

Prescription & fees included

Go directly to the lab, no extra fees

Easy to understand results

With friendly doctor's notes & guidance

Fast & convenient

Lab visit as quick as 10 mins in & out

What's this test for?

This test is ideal if you're experiencing unexplained fatigue, weakness, digestive issues, or tingling in your hands and feet that might indicate pernicious anemia or vitamin B12 deficiency. It helps identify if your immune system is attacking your stomach lining, which can prevent proper absorption of vitamin B12 and lead to serious health issues. Many people use this test when they have low B12 levels or a family history of autoimmune conditions affecting the stomach.

How should I prepare for this test?

No special preparation is typically required for this test. You can take your regular medications and eat normally before your blood draw. However, it's always best to inform your healthcare provider about any medications or supplements you're taking, especially immunosuppressants or treatments for autoimmune conditions, as they may want to note this in your medical record.

What's included in this test?

Parietal Cell Ab, Elisa

This test measures Parietal Cell Antibodies, which are immune system proteins that attack the cells in your stomach lining responsible for producing intrinsic factor. Intrinsic factor is essential for absorbing vitamin B12, so when these antibodies are present, they can lead to vitamin B12 deficiency and pernicious anemia. This test is particularly important for understanding autoimmune gastritis and identifying your risk for serious nutritional deficiencies that can affect your energy, nerves, and overall health.

What happens after I get my results?
You'll receive detailed doctor notes in simple language explaining what your parietal cell antibody levels mean for your digestive health and risk of developing pernicious anemia. These notes include personalized recommendations like vitamin B12 supplementation strategies, dietary adjustments, or whether you should follow up with a gastroenterologist for further evaluation. You'll also get the standard lab report and can track your antibody levels over time using our trends feature to monitor your autoimmune condition.
When will I get my results?
Most ELISA antibody tests are processed within 3-5 business days after your blood sample reaches the laboratory. You'll receive an email notification as soon as your results are ready to view in your secure online account. If your results show positive antibodies, you may want to discuss follow-up testing or treatment with your healthcare provider promptly.
Who should consider getting this test?
This test is important for people with unexplained vitamin B12 deficiency, those experiencing symptoms of pernicious anemia like extreme fatigue and neurological issues, and individuals with a family history of autoimmune gastritis or pernicious anemia. It's also valuable for people with other autoimmune conditions like thyroid disease or type 1 diabetes, as these conditions often occur together.
What symptoms indicate I may need this test?
Common symptoms that suggest you might need this test include persistent fatigue and weakness, pale or yellowish skin, tingling or numbness in hands and feet, difficulty walking or balance problems, memory issues or brain fog, and digestive problems like loss of appetite or diarrhea. These symptoms often develop gradually as vitamin B12 deficiency worsens over time.
What is pernicious anemia and why does it matter?
Pernicious anemia is a condition where your body can't absorb enough vitamin B12 because your immune system attacks the stomach cells that produce intrinsic factor, a protein necessary for B12 absorption. This matters because vitamin B12 is essential for making red blood cells, maintaining healthy nerves, and producing DNA. Without treatment, pernicious anemia can lead to serious neurological damage, severe anemia, and increased risk of stomach cancer.
What does a positive parietal cell antibody result mean?
A positive result means your immune system is producing antibodies against your stomach's parietal cells, indicating autoimmune gastritis. This suggests you're at higher risk for developing pernicious anemia and vitamin B12 deficiency if you don't already have it. About 90% of people with pernicious anemia test positive for these antibodies, though not everyone with positive antibodies will develop pernicious anemia.
How often should I retest my parietal cell antibodies?
If your initial test is positive, you typically don't need to retest the antibodies frequently since they tend to remain present once detected. Instead, your doctor will likely focus on monitoring your vitamin B12 levels, complete blood count, and symptoms every 6-12 months. If your initial test is negative but you have strong clinical suspicion for autoimmune gastritis, your doctor may recommend retesting in 1-2 years.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at [email protected], and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at [email protected]. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email [email protected].
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email [email protected].

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

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Demo results
Parietal Cell Antibody Negative
Demo results
Negative Positive
Negative

What this means

Your test came back negative, meaning no parietal cell antibodies were detected in your blood. This is the expected and healthy result, suggesting your immune system is not attacking your stomach lining cells. If you're experiencing symptoms of B12 deficiency, other causes should be explored with your healthcare provider.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More complex tests, such as hormone panels, may take up to 10–15 business days due to their complexity.
Here’s how easy it is to get blood work done on your terms
Choose a checkup
Order your test Save a trip to the doctor. Your results will come with clear, friendly explanations. Takes 2 minutes
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Book an appointment Visit any of our 4,000 nearby lab locations to have your samples collected. Book or walk-in
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Get results Receive a clear, easy-to-digest health report by email & SMS within a few business days. Get answers, fast

Blood Test for Fatigue and B12 Deficiency

Google
3,138 reviews
  • Detects stomach lining antibodies
  • Checks for stomach tissue attack
  • Identifies possible autoimmune issues

1,000,000+ blood tests later, here's what our customers say

Google reviews 3138 reviews Next
Still got questions? Text our super-cool support team at 754-799-7833 to get help finding your ideal checkup.