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Neurofilament Light Chain test for detecting brain health and neurological disease indicators

Blood Test for Brain Health and Memory Issues

Neurofilament Light Chain (NfL), Plasma

Google
3,138 reviews
  • Checks brain cell damage levels
  • Measures nerve health in blood
  • Detects neurological disease indicators
First results as soon as overnight*

90 day happiness guarantee

We stand behind our service

Prescription & fees included

Go directly to the lab, no extra fees

Easy to understand results

With friendly doctor's notes & guidance

Fast & convenient

Lab visit as quick as 10 mins in & out

90 day happiness guarantee

We stand behind our service

Prescription & fees included

Go directly to the lab, no extra fees

Easy to understand results

With friendly doctor's notes & guidance

Fast & convenient

Lab visit as quick as 10 mins in & out

What's this test for?

This test is ideal if you're concerned about brain health, experiencing memory issues, or have a family history of neurological conditions like Alzheimer's or multiple sclerosis. It measures neurofilament light chain levels in your blood, which indicates nerve cell damage or degeneration. Many people use this test to catch early signs of neurological problems or to monitor disease progression if they've already been diagnosed.

How should I prepare for this test?

No biotin: 72 hours

You should stop taking biotin supplements at least 72 hours before your blood draw. Biotin can interfere with the test results and cause inaccurate readings. Other than avoiding biotin, no special fasting or preparation is required for this test.

What's included in this test?

This test measures neurofilament light chain (NfL), a protein released when nerve cells are damaged or dying. Elevated NfL levels can indicate active neurological damage from conditions like multiple sclerosis, Alzheimer's disease, traumatic brain injury, or other neurodegenerative disorders. This single biomarker provides valuable insight into overall brain health and the rate of nerve cell damage happening in your body.

What happens after I get my results?
You'll receive detailed doctor notes in simple language explaining what your neurofilament levels mean for your brain health and nerve function. These notes include personalized recommendations like lifestyle changes to support brain health, when to follow up with a neurologist, and whether additional testing may be helpful. You'll also get the standard lab report and can track your levels over time using our trends feature, which is especially valuable for monitoring progression or improvement.
Who should consider getting this test?
This test is valuable for people with unexplained neurological symptoms like memory problems, balance issues, or numbness. It's also helpful for those with a family history of Alzheimer's, MS, or other brain diseases, and for monitoring disease progression in people already diagnosed with neurological conditions. Athletes with a history of concussions may also benefit from checking their brain health.
What symptoms indicate I may need this test?
Consider this test if you're experiencing memory loss, confusion, difficulty concentrating, balance problems, numbness or tingling, muscle weakness, or changes in coordination. It's also relevant if you've had repeated head injuries, notice your thinking is getting slower, or have unexplained vision problems. These symptoms could indicate nerve damage that this test can help identify.
How can I naturally support my brain and nerve health?
Supporting brain health involves regular aerobic exercise, which increases blood flow to the brain and promotes nerve cell health. A Mediterranean-style diet rich in omega-3 fatty acids, berries, leafy greens, and nuts provides essential nutrients for brain function. Prioritizing quality sleep, managing stress through meditation or mindfulness, staying mentally active with puzzles and learning, and maintaining social connections all help protect against neurological decline.
What is neurofilament light chain and why does it matter?
Neurofilament light chain (NfL) is a structural protein found inside nerve cells that acts like scaffolding to maintain cell shape. When nerve cells are damaged or dying, NfL is released into the bloodstream. Measuring NfL levels helps doctors detect active nerve damage early, even before symptoms become severe, making it a valuable marker for monitoring brain health and neurological disease activity.
What does high neurofilament light chain mean?
Elevated NfL levels indicate active nerve cell damage or degeneration in your brain or nervous system. This could suggest conditions like multiple sclerosis, Alzheimer's disease, Parkinson's disease, traumatic brain injury, or other neurodegenerative disorders. Higher levels generally correlate with more active disease or faster progression, though levels also naturally increase slightly with normal aging.
How often should I retest my neurofilament levels?
If you're monitoring a diagnosed neurological condition, your doctor may recommend retesting every 6-12 months to track disease progression or response to treatment. For baseline health monitoring in people with risk factors, annual testing may be appropriate. If your initial results are elevated, your doctor will likely want to retest sooner, possibly in 3-6 months, to establish a trend and determine if levels are stable, increasing, or decreasing.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at [email protected], and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at [email protected]. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email [email protected].
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email [email protected].

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

You get clinical lab reports & simplified health insights.
Save time & gas, go straight to the lab. Our doctors cover the rest.
Results start landing the next day after your lab visit.*
We don’t sell or share your data. Your time & privacy matter.
US-licensed doctors have your back if things get unclear.
No hidden fees, nice discounts for regular checkups.
Save a trip to the doctor, go directly to the lab
Instant orders, results often overnight*
Results explained in simple language
Reviewed by US licensed doctors
Fast & confidential, we never sell or share your data
No insurance needed, transparent pricing
Demo results
Neurofilament Light Chain (NfL) 22.5 pg/mL
Demo results
Normal < 20 Elevated ≥ 20
22.5 pg/mL

What this means

Your neurofilament light chain level is slightly elevated above the typical reference range. While this could be within normal variation for your age, it may indicate mild nerve cell activity or damage that warrants monitoring. Elevated levels can be associated with neurological conditions, but a single test doesn't provide a diagnosis.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More complex tests, such as hormone panels, may take up to 10–15 business days due to their complexity.
Here’s how easy it is to get blood work done on your terms
Choose a checkup
Order your test Save a trip to the doctor. Your results will come with clear, friendly explanations. Takes 2 minutes
Book a lab
Book an appointment Visit any of our 4,000 nearby lab locations to have your samples collected. Book or walk-in
Choose a checkup
Get results Receive a clear, easy-to-digest health report by email & SMS within a few business days. Get answers, fast

Blood Test for Brain Health and Memory Issues

Google
3,138 reviews
  • Checks brain cell damage levels
  • Measures nerve health in blood
  • Detects neurological disease indicators

1,000,000+ blood tests later, here's what our customers say

Google reviews 3138 reviews Next
Still got questions? Text our super-cool support team at 754-799-7833 to get help finding your ideal checkup.