What's this test for?

This test is ideal if you're experiencing unexplained muscle weakness, especially in your eyes, face, or limbs, along with unusual fatigue that worsens with activity. It helps diagnose Myasthenia Gravis, an autoimmune condition where your immune system interferes with nerve signals to your muscles. Many people use this test when they have double vision, drooping eyelids, difficulty swallowing or speaking, or weakness that improves with rest but their doctors haven't found the cause yet.

What happens after I get my results?

You'll receive detailed doctor notes in simple language explaining what your antibody levels mean for your muscle function and nerve communication. These notes include personalized guidance on whether you should consult with a neurologist, what treatment options might be appropriate, and lifestyle adjustments that can help manage symptoms. You'll also get the standard lab report and can track your antibody levels over time using our trends feature, which is especially helpful if you're monitoring disease progression or treatment effectiveness.

What's included in this test?

This panel measures anti-MuSK (muscle-specific receptor tyrosine kinase) antibodies and anti-LRP4 (low-density lipoprotein receptor-related protein 4) antibodies. This specialized panel checks for two specific antibodies that interfere with the proteins that help nerve signals reach your muscles properly, causing the characteristic muscle weakness of Myasthenia Gravis. Testing for both antibodies is important because they appear in different patients with MG, and detecting them helps confirm the diagnosis when other antibody tests come back negative.

When will I get my results?

Results for this specialized antibody panel typically take 7-10 business days from when the lab receives your sample. The testing process requires sophisticated immunoassay techniques to detect these specific antibodies accurately. You'll receive an email notification as soon as your results are ready, and you can access them securely through your online account along with the detailed doctor notes.

Who should consider getting this test?

This test is specifically for people suspected of having Myasthenia Gravis who have tested negative for the more common acetylcholine receptor antibodies. It's particularly important if you're experiencing muscle weakness that worsens with use, drooping eyelids, double vision, difficulty swallowing, or breathing problems. Your doctor may recommend this test if they suspect MG based on your symptoms and clinical examination but need confirmation through specific antibody testing.

What symptoms indicate I may need this test?

Key symptoms include drooping eyelids that worsen as the day goes on, double vision, difficulty swallowing or chewing (especially toward the end of meals), slurred speech, weakness in your arms or legs that improves with rest, and trouble breathing or shortness of breath. Many people also experience facial muscle weakness, making it hard to smile or close their eyes completely. If these symptoms fluctuate throughout the day and worsen with activity, it may indicate Myasthenia Gravis.

How can I manage muscle weakness from Myasthenia Gravis?

Managing MG involves balancing activity with adequate rest periods throughout the day, as muscle weakness typically worsens with use and improves with rest. Avoid extreme temperatures, as heat can worsen symptoms, and prioritize good sleep hygiene with 7-9 hours per night. Break tasks into smaller segments with rest breaks, use assistive devices when needed, and work with a physical therapist to maintain muscle strength without overexertion. Always follow your neurologist's treatment plan if medications are prescribed.

What is Myasthenia Gravis and why do these antibodies matter?

Myasthenia Gravis is an autoimmune condition where your immune system produces antibodies that block or damage proteins needed for muscles to receive signals from nerves. MuSK and LRP4 are proteins at the neuromuscular junction that help organize and maintain the receptors that receive these nerve signals. When antibodies attack these proteins, the communication between nerves and muscles breaks down, causing progressive muscle weakness and fatigue that's characteristic of MG.

What does a positive result mean?

A positive result means antibodies against MuSK or LRP4 were detected in your blood, which confirms a diagnosis of Myasthenia Gravis. This is valuable information because it explains your muscle weakness symptoms and guides your doctor toward appropriate treatment options. While MG is a chronic condition, it's manageable with proper treatment, which may include medications that improve nerve-muscle communication, immunosuppressants, or other therapies tailored to antibody-positive MG.

How often should I retest these antibodies?

After initial diagnosis, your neurologist may retest antibody levels periodically to monitor disease activity and treatment response, typically every 6-12 months or when symptoms significantly change. However, antibody levels don't always correlate perfectly with symptom severity, so testing frequency is individualized based on your clinical status. If you're starting new treatments or experiencing symptom changes, your doctor may order retesting sooner to assess treatment effectiveness.

Getting your blood test with us is easy, private & backed by the power of science.Long story short: In the test options, use the filters or search box to narrow your choices and find the test you want. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy! If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

How do I know which test to get?

In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option. Just text or call us at 754-799-7833, email us at support@privatemdlabs.com, and we'll gladly help you. We've got your back and reply quickly.

When will my lab results be available?

Most test results will be available within 1–3 business days. Once they're ready, we'll send an email and text message to let you know. After your blood draw, just hang tight and don't worry – we'll keep you updated and in the loop! If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com, and we'll gladly help you.

Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?

Absolutely! We totally understand that errors can happen. No worries, we're here to help you. Just reach out to us via text at 754-799-7833 or shoot us an email at support@privatemdlabs.com. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you. There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out. Our lab requires an address to be listed to generate an order.

Do you accept health insurance?

Only HSA & FSA is accepted. Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts. This policy applies to all insurance companies, including federal health insurance programs like Medicare. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com.

Can I cancel my order?

Yes. We get it – sometimes your needs change. As long as your samples haven’t been collected yet, we’re happy to help you cancel your order. If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com. You can read more about our cancellation policy here.

How can I find a lab location near me?

During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp). Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

Muscle Weakness Test - MuSK & LRP4 Antibodies

Getting your blood test with us is easy, private & backed by the power of science.

Long story short:

In the test options, use the filters or search box to narrow your choices and find the test you want.
If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!

754-799-7833

[email protected]

Blood Test for Muscle Weakness and Fatigue Issues

MuSK and LRP4 Antibodies Panel

90 day happiness guarantee

Prescription & fees included

Easy to understand results

Fast & convenient

90 day happiness guarantee

Prescription & fees included

Easy to understand results

Fast & convenient

What's this test for?

What's included in this test?

What happens after I get my results?

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

Blood Test for Muscle Weakness and Fatigue Issues

90 day happiness guarantee

Prescription & fees included

Easy to understand results

Fast & convenient

1,000,000+ blood tests later, here's what our customers say