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Mitochondrial antibody test for unexplained fatigue and autoimmune liver concerns

Blood Test for Unexplained Fatigue and Liver Issues

Mitochondrial Antibody with Reflex to Titer

Google
3,138 reviews
  • Pinpoint the cause of unexplained fatigue
  • Reveal underlying autoimmune issues effortlessly
  • Clarify liver health concerns with precision
First results as soon as overnight*

90 day happiness guarantee

We stand behind our service

Prescription & fees included

Go directly to the lab, no extra fees

Easy to understand results

With friendly doctor's notes & guidance

Fast & convenient

Lab visit as quick as 10 mins in & out

90 day happiness guarantee

We stand behind our service

Prescription & fees included

Go directly to the lab, no extra fees

Easy to understand results

With friendly doctor's notes & guidance

Fast & convenient

Lab visit as quick as 10 mins in & out

What's this test for?

This test is ideal if you're experiencing unexplained, persistent fatigue, itchy skin, or digestive issues that won't go away. It helps identify autoimmune conditions affecting your liver, particularly primary biliary cirrhosis (PBC), which can cause these symptoms long before serious liver damage occurs. Many people use this test when standard fatigue tests come back normal but they still feel something is wrong.

What's included in this test?

Mitochondrial Antibody with Reflex to Titer

This test measures Mitochondrial Antibody (AMA) levels in your blood, which are specific markers for autoimmune liver disease. If positive, it automatically performs a titer test to measure the concentration of these antibodies, providing more detailed information about the strength of your immune response. These measurements help distinguish primary biliary cirrhosis from other liver conditions and guide appropriate treatment decisions.

What happens after I get my results?

You'll receive detailed doctor notes in simple language explaining what your mitochondrial antibody levels mean for your liver health and energy levels. These notes include personalized recommendations like lifestyle modifications, when to follow up with a hepatologist or gastroenterologist, and what additional tests might be helpful. You'll also get the standard lab report and can track your antibody levels over time using our trends feature, which is especially useful if you're monitoring an autoimmune condition.

When will I get my results?
Most results are available within 2-4 business days after your sample reaches the lab. The reflex titer, if needed, may add an additional 1-2 days to ensure comprehensive results. You'll receive an email notification as soon as your results are ready to view in your secure online account.
Who should consider getting this test?
This test is important for people with unexplained chronic fatigue, persistent itching without a rash, or elevated liver enzymes found on routine blood work. It's also valuable if you have other autoimmune conditions like thyroid disease or rheumatoid arthritis, as autoimmune diseases often occur together. Women over 40 are at higher risk for primary biliary cirrhosis and should consider this test if experiencing these symptoms.
What symptoms indicate I may need this test?
Common signs include persistent fatigue that doesn't improve with rest, unexplained itching (especially on hands and feet), dry eyes and dry mouth, yellowing of skin or eyes, and discomfort in the upper right abdomen. You might also experience digestive issues, unexplained weight changes, or dark urine. If you have any combination of these symptoms, especially lasting more than a few weeks, this test can help identify the underlying cause.
What does a positive mitochondrial antibody result mean?
A positive result, especially with a high titer, strongly suggests primary biliary cirrhosis (PBC), an autoimmune condition where your immune system attacks the bile ducts in your liver. This doesn't mean you have cirrhosis yet, as the disease progresses slowly over many years. Low positive levels might also appear in other liver conditions like chronic hepatitis or may occasionally occur without significant liver disease, which is why follow-up with a specialist is important.
What is primary biliary cirrhosis and why does it matter?
Primary biliary cirrhosis (PBC) is an autoimmune disease where your body mistakenly attacks the small bile ducts in your liver, causing inflammation and scarring over time. Early detection matters because treatment can slow progression, manage symptoms, and prevent serious complications. Without treatment, PBC can eventually lead to liver damage, but when caught early and managed properly, most people live normal, healthy lives.
How can I naturally support my liver health?
Supporting liver health starts with avoiding alcohol and limiting processed foods, as these put extra stress on your liver. Eat plenty of antioxidant-rich foods like leafy greens, berries, and cruciferous vegetables, and stay well-hydrated throughout the day. Regular exercise, maintaining a healthy weight, and getting adequate sleep also support liver function and help manage autoimmune conditions.
How often should I retest my mitochondrial antibodies?
If your initial test is negative but symptoms persist, retesting in 6-12 months may be recommended as antibodies can develop over time. For those with a positive result and diagnosed PBC, your doctor will typically monitor liver function every 3-6 months, though the antibody test itself doesn't usually need frequent repeating since levels tend to remain stable once positive. Your healthcare provider will determine the best monitoring schedule based on your individual situation and treatment response.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at [email protected], and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at [email protected]. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email [email protected].
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email [email protected].

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

You get clinical lab reports & simplified health insights.
Save time & gas, go straight to the lab. Our doctors cover the rest.
Results start landing the next day after your lab visit.*
We don’t sell or share your data. Your time & privacy matter.
US-licensed doctors have your back if things get unclear.
No hidden fees, nice discounts for regular checkups.
Save a trip to the doctor, go directly to the lab
Instant orders, results often overnight*
Results explained in simple language
Reviewed by US licensed doctors
Fast & confidential, we never sell or share your data
No insurance needed, transparent pricing
Demo results
Mitochondrial Antibody (AMA) Negative
Demo results
Negative Positive
Negative

What this means

Your test came back negative, meaning no mitochondrial antibodies were detected in your blood. This makes primary biliary cirrhosis unlikely and is a reassuring result for your liver health.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More complex tests, such as hormone panels, may take up to 10–15 business days due to their complexity.
Here’s how easy it is to get blood work done on your terms
Choose a checkup
Order your test Save a trip to the doctor. Your results will come with clear, friendly explanations. Takes 2 minutes
Book a lab
Book an appointment Visit any of our 4,000 nearby lab locations to have your samples collected. Book or walk-in
Choose a checkup
Get results Receive a clear, easy-to-digest health report by email & SMS within a few business days. Get answers, fast

Blood Test for Unexplained Fatigue and Liver Issues

Google
3,138 reviews
  • Pinpoint the cause of unexplained fatigue
  • Reveal underlying autoimmune issues effortlessly
  • Clarify liver health concerns with precision

1,000,000+ blood tests later, here's what our customers say

Google reviews 3138 reviews Next
Still got questions? Text our super-cool support team at 754-799-7833 to get help finding your ideal checkup.