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Advanced cholesterol particle analysis for assessing heart disease risk and cardiovascular health

Advanced Cholesterol Test for Heart Disease Risk

Lipoprotein Fractionation, NMR

Google
3,138 reviews
  • Analyzes your cholesterol particle sizes.
  • Checks heart health through blood.
  • Measures detailed cholesterol levels.
First results as soon as overnight*

90 day happiness guarantee

We stand behind our service

Prescription & fees included

Go directly to the lab, no extra fees

Easy to understand results

With friendly doctor's notes & guidance

Fast & convenient

Lab visit as quick as 10 mins in & out

90 day happiness guarantee

We stand behind our service

Prescription & fees included

Go directly to the lab, no extra fees

Easy to understand results

With friendly doctor's notes & guidance

Fast & convenient

Lab visit as quick as 10 mins in & out

What's this test for?

This test is ideal if you're concerned about your heart health and want to go beyond basic cholesterol numbers. It's especially useful if you have a family history of heart disease, are at intermediate or high cardiovascular risk, or if you're already on cholesterol-lowering medication and want to see how well it's working. This advanced analysis looks at cholesterol particle sizes and numbers, giving you a much more detailed picture of your actual risk for heart disease than traditional cholesterol tests.

How should I prepare for this test?

Fasting: 12 hours

You should fast for 12 hours before your blood draw. This means no food or beverages except water during that time. Fasting ensures accurate measurements of your lipid particles and helps provide the most reliable assessment of your cardiovascular risk. Try to schedule your appointment in the morning so fasting overnight covers most of this period.

What's included in this test?

Lipoprotein Fractionation, NMR

This test measures Lipoprotein Fractionation using Nuclear Magnetic Resonance (NMR) technology. This advanced analysis breaks down your cholesterol into different particle sizes and counts, including small dense LDL particles that are particularly harmful for heart health, HDL particle numbers, and VLDL sizes. Unlike basic cholesterol tests that only show total amounts, this gives you a detailed picture of particle characteristics that more accurately predict cardiovascular disease risk and help guide more targeted treatment strategies.

What happens after I get my results?
You'll receive detailed doctor notes in simple language explaining what your cholesterol particle sizes mean for your heart health and cardiovascular risk. These notes include personalized recommendations like dietary changes, exercise strategies, supplement suggestions, or whether your current medication is working effectively. You'll also get the standard lab report and can track your lipid profile over time using our trends feature to see how your lifestyle changes or treatments are improving your heart health markers.
Who should consider getting this test?
This test is valuable for anyone with intermediate to high cardiovascular risk based on family history, age, diabetes, high blood pressure, or existing heart disease. It's particularly helpful if you have borderline cholesterol levels and need clarity on your true risk, or if standard cholesterol tests don't fully explain your cardiovascular concerns. People already taking statins or other lipid-lowering medications can use this test to monitor how well their treatment is working at the particle level.
What symptoms indicate I may need this test?
While cholesterol issues typically don't cause obvious symptoms, you should consider this test if you experience chest discomfort during physical activity, unexplained shortness of breath, or have a family history of early heart attacks or strokes. This test is also important if you have risk factors like persistent fatigue despite normal activity, high blood pressure, diabetes, or obesity—all conditions that increase cardiovascular risk and benefit from detailed cholesterol particle analysis.
How can I naturally support healthy cholesterol particle profiles?
Focus on heart-healthy fats from sources like olive oil, avocados, nuts, and fatty fish rich in omega-3s, which improve particle quality. Regular aerobic exercise like brisk walking, swimming, or cycling helps increase beneficial HDL particles and reduce harmful small dense LDL particles. Eating more fiber from vegetables, fruits, and whole grains, managing stress, maintaining a healthy weight, and avoiding trans fats and excessive refined carbohydrates all contribute to healthier cholesterol particle profiles.
What are cholesterol particles and why do they matter more than total cholesterol?
Cholesterol particles are like tiny packages that carry cholesterol through your bloodstream. The size and number of these particles matter more than just total cholesterol amounts because small, dense LDL particles can more easily penetrate artery walls and cause plaque buildup, while larger, fluffier particles are less harmful. Two people can have the same LDL cholesterol number, but the person with more small dense particles has significantly higher heart disease risk—that's what this NMR test reveals.
What does it mean if I have high numbers of small LDL particles?
High numbers of small, dense LDL particles indicate an increased risk for cardiovascular disease because these particles more easily infiltrate artery walls and contribute to plaque formation. This pattern is often associated with insulin resistance, prediabetes, high triglycerides, and metabolic syndrome. The good news is that lifestyle changes like reducing refined carbs and sugars, increasing physical activity, and eating more healthy fats can help shift your particle profile toward larger, less dangerous particles.
How often should I retest my lipoprotein particle profile?
If you're making lifestyle changes or just started cholesterol medication, retest in 3-6 months to see how your particle profile is responding. Once your levels are optimized and stable, annual testing is typically sufficient for monitoring. If you have existing cardiovascular disease or multiple risk factors, your healthcare provider may recommend more frequent testing every 6 months to closely track your progress and adjust treatment as needed.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at [email protected], and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at [email protected]. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email [email protected].
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email [email protected].

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

You get clinical lab reports & simplified health insights.
Save time & gas, go straight to the lab. Our doctors cover the rest.
Results start landing the next day after your lab visit.*
We don’t sell or share your data. Your time & privacy matter.
US-licensed doctors have your back if things get unclear.
No hidden fees, nice discounts for regular checkups.
Save a trip to the doctor, go directly to the lab
Instant orders, results often overnight*
Results explained in simple language
Reviewed by US licensed doctors
Fast & confidential, we never sell or share your data
No insurance needed, transparent pricing
Demo results
Small LDL Particle Number 1450 nmol/L
Demo results
Low Optimal < 1000 High
1450 nmol/L

What this means

Your small LDL particle count is elevated, which indicates a higher risk for cardiovascular disease. Small, dense LDL particles are more likely to penetrate artery walls and contribute to plaque buildup than larger particles. This pattern is often seen with insulin resistance, high triglycerides, or metabolic syndrome and responds well to lifestyle modifications.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More complex tests, such as hormone panels, may take up to 10–15 business days due to their complexity.
Here’s how easy it is to get blood work done on your terms
Choose a checkup
Order your test Save a trip to the doctor. Your results will come with clear, friendly explanations. Takes 2 minutes
Book a lab
Book an appointment Visit any of our 4,000 nearby lab locations to have your samples collected. Book or walk-in
Choose a checkup
Get results Receive a clear, easy-to-digest health report by email & SMS within a few business days. Get answers, fast

Advanced Cholesterol Test for Heart Disease Risk

Google
3,138 reviews
  • Analyzes your cholesterol particle sizes.
  • Checks heart health through blood.
  • Measures detailed cholesterol levels.

1,000,000+ blood tests later, here's what our customers say

Google reviews 3138 reviews Next
Still got questions? Text our super-cool support team at 754-799-7833 to get help finding your ideal checkup.