Interleukin-4 (IL-4), Serum
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Blood Test for Allergies and Immune System Function
Interleukin-4 (IL-4), Serum
- Measures immune system protein levels
- Checks for allergy-related inflammation
- Monitors immune response status
$525
Example results
First results as soon as overnight*
90 day happiness guarantee
We stand behind our service
Prescription & fees included
Go directly to the lab, no extra fees
Easy to understand results
With friendly doctor's notes & guidance
Fast & convenient
Lab visit as quick as 10 mins in & out
90 day happiness guarantee
We stand behind our service
Prescription & fees included
Go directly to the lab, no extra fees
Easy to understand results
With friendly doctor's notes & guidance
Fast & convenient
Lab visit as quick as 10 mins in & out
What's this test for?
This test is ideal if you're dealing with chronic allergies, asthma, or unexplained inflammatory conditions that affect your quality of life. It helps identify whether your immune system is producing too much or too little IL-4, a key protein that regulates allergic responses and inflammation. Many people use this test when they suspect their immune system is overreacting to allergens or when allergy treatments aren't working as expected.
How should I prepare for this test?
No special preparation is typically required for this test. You can maintain your normal diet, medications, and daily routine before having your blood drawn. However, if you're taking immunosuppressive medications or have recently started new allergy treatments, let your healthcare provider know, as these may affect your results. It's helpful to get tested when you're not experiencing an acute allergic reaction for a more accurate baseline measurement.
What's included in this test?
This test measures Interleukin-4 (IL-4), a cytokine protein that plays a central role in regulating your body's allergic and inflammatory responses. IL-4 is particularly important because it controls how your immune system reacts to allergens like pollen, food, or environmental triggers, and it influences the production of antibodies that cause allergic symptoms. Understanding your IL-4 levels can help explain persistent allergies, asthma flare-ups, or inflammatory conditions that haven't responded well to standard treatments.
What happens after I get my results?
You'll receive detailed doctor notes in simple language explaining what your IL-4 levels mean for your immune function and allergy response. These notes include personalized recommendations like dietary changes, potential allergen avoidance strategies, or whether you should consider consulting an allergist or immunologist. You'll also get the standard lab report and can track your IL-4 levels over time using our trends feature to see how interventions or treatments are affecting your immune response.
When will I get my results?
Results for IL-4 testing typically take 5-7 business days from when the lab receives your sample. This test requires specialized immunoassay analysis, which takes longer than routine blood work. You'll receive an email notification as soon as your results are available, and you can access them immediately through your secure online account with detailed doctor notes to help you understand what they mean.
Who should consider getting this test?
This test is valuable for anyone with chronic allergies, asthma, eczema, or recurrent allergic reactions that aren't well controlled with standard medications. It's also useful for people working with immunologists to understand autoimmune conditions or for those participating in allergy research or clinical trials. If you have a family history of severe allergies or immune disorders, this test can provide insights into your immune system's regulatory mechanisms.
What symptoms indicate I may need this test?
Consider this test if you experience persistent sneezing, runny nose, itchy eyes, or skin rashes that don't respond well to antihistamines. Other indicators include frequent asthma attacks, chronic hives, food allergies that seem to be worsening, or eczema flare-ups. If you find yourself constantly dealing with allergy symptoms despite avoiding known triggers, measuring IL-4 can help identify whether your immune system is overproducing this inflammatory protein.
How can I naturally support healthy immune balance?
Supporting balanced immune function starts with an anti-inflammatory diet rich in omega-3 fatty acids from fish, flaxseeds, and walnuts, which can help regulate inflammatory responses. Managing stress through meditation, adequate sleep, and regular moderate exercise helps prevent immune system overactivity. Probiotics and gut-healthy foods like yogurt, kefir, and fermented vegetables may help balance immune responses, and avoiding processed foods and excess sugar can reduce inflammatory triggers.
What is Interleukin-4 and why does it matter?
Interleukin-4 is a signaling protein produced by certain white blood cells that tells your immune system how to respond to potential threats. It's particularly important because it directs the production of IgE antibodies, which are responsible for allergic reactions like hay fever, food allergies, and asthma. When IL-4 levels are too high, your body may overreact to harmless substances like pollen or pet dander, but when levels are too low, you might have difficulty mounting appropriate immune responses.
What does high IL-4 mean?
Elevated IL-4 levels typically indicate your immune system is in an overactive allergic state, which can manifest as severe allergies, asthma, or chronic inflammatory conditions. High levels suggest your body is producing excessive IgE antibodies that cause allergic symptoms like wheezing, itching, swelling, or hives. This information can help your doctor understand why standard allergy treatments might not be working and may guide decisions about targeted immunotherapy or biologic medications.
How often should I retest my IL-4 levels?
If you're undergoing treatment for allergies or immune conditions, retesting every 3-6 months can help track whether interventions are working. For those monitoring chronic conditions like asthma or eczema, testing annually or when symptoms significantly change is usually sufficient. If you're trying new allergy medications or immunotherapy, your doctor may recommend retesting 2-3 months after starting treatment to assess effectiveness.
How’s this work?
Long story short:
- In the test options, use the filters or search box to narrow your choices and find the test you want.
- If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
- Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
- If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
- When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
- Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
- You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy! If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
How do I know which test to get?
Just text or call us at 754-799-7833, email us at [email protected], and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Just reach out to us via text at 754-799-7833 or shoot us an email at [email protected]. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.
There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.
Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.
This policy applies to all insurance companies, including federal health insurance programs like Medicare.
If you have any questions, please text us at 754-799-7833 or email [email protected].
Can I cancel my order?
We get it – sometimes your needs change.
As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.
If you have any further questions, please text us at 754-799-7833 or email [email protected].
You can read more about our cancellation policy here.
How can I find a lab location near me?
Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.
If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
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Demo results
Interleukin-4 (IL-4)
28.5 pg/mL
Demo results
Low
Optimal 2.0 - 20.0
High
28.5 pg/mL
What this means
Your IL-4 levels are elevated, indicating your immune system is in an overactive allergic state. This may explain persistent allergy symptoms like sneezing, itching, or asthma that haven't responded well to standard treatments. Elevated IL-4 suggests your body is producing excess IgE antibodies that trigger allergic reactions.
Recommended actions
Follow an anti-inflammatory diet rich in omega-3 fatty acids from fish, flaxseeds, and walnuts
Identify and minimize exposure to known allergen triggers in your environment
Consider probiotics and gut-healthy foods to help balance immune responses
Consult with an allergist about targeted immunotherapy or biologic treatments
Retest in 3-6 months to monitor how interventions affect your immune response
* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More complex tests, such as hormone panels, may take up to 10–15 business days due to their complexity.
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Get answers, fast
Blood Test for Allergies and Immune System Function
- Measures immune system protein levels
- Checks for allergy-related inflammation
- Monitors immune response status
$525
Example results
1,000,000+ blood tests later, here's what our customers say
3138 reviews
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