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Immunofixation serum test for detecting multiple myeloma and blood cancers early

Blood Test for Fatigue, Bone Pain, and Frequent Infections

Immunofixation, Serum

Google
3,138 reviews
  • Pinpoint the cause of unexplained fatigue
  • Reveal hidden immune system issues
  • Clarify the source of chronic infections
First results as soon as overnight*

90 day happiness guarantee

We stand behind our service

Prescription & fees included

Go directly to the lab, no extra fees

Easy to understand results

With friendly doctor's notes & guidance

Fast & convenient

Lab visit as quick as 10 mins in & out

90 day happiness guarantee

We stand behind our service

Prescription & fees included

Go directly to the lab, no extra fees

Easy to understand results

With friendly doctor's notes & guidance

Fast & convenient

Lab visit as quick as 10 mins in & out

What's this test for?

This test is ideal if you're experiencing unexplained fatigue, frequent infections, bone pain, or weakness that won't go away. It helps detect abnormal proteins in your blood that may indicate blood cancers like multiple myeloma, lymphomas, or leukemia, or other immune system disorders. Many people use this test when their doctor notices unusual protein levels in routine blood work and wants to identify the specific type and cause.

How should I prepare for this test?

Overnight fasting is preferred before this test, which means no food or drinks except water for 8-12 hours prior to your blood draw. You can take your regular medications with water unless your doctor advises otherwise. Schedule your test for the morning if possible to make fasting easier, and stay well-hydrated by drinking plenty of water.

What's included in this test?

Immunofixation, Serum

This test uses immunofixation electrophoresis to identify and characterize specific abnormal proteins (immunoglobulins) in your blood serum. It's particularly important for detecting monoclonal proteins that can indicate blood disorders or cancers, helping distinguish between different types of protein abnormalities. This detailed analysis provides crucial information about your immune system function and can reveal conditions that may not show up on routine blood work.

What happens after I get my results?
You'll receive detailed doctor notes in simple language explaining what your immunofixation results mean and whether abnormal proteins were detected. These notes include personalized recommendations such as follow-up testing, lifestyle adjustments, or whether you should consult with a hematologist or oncologist for further evaluation. You'll also get the standard lab report and can track your protein patterns over time using our trends feature to monitor any changes.
Who should consider getting this test?
This test is important for anyone with unexplained symptoms like persistent fatigue, bone pain, frequent infections, or unexplained weight loss. It's also recommended if routine blood work shows abnormal protein levels, elevated calcium, anemia, or kidney problems. People with a family history of multiple myeloma or blood disorders, or those over 65 with concerning symptoms, should discuss this test with their doctor.
What symptoms indicate I may need this test?
Key symptoms include persistent bone pain (especially in the back or ribs), extreme fatigue that doesn't improve with rest, frequent infections, unexplained bruising or bleeding, and numbness or tingling in the extremities. You might also experience excessive thirst, confusion, weakness, or unintended weight loss. If you have multiple symptoms that can't be explained by other conditions, this test can help identify underlying causes.
What is a monoclonal protein and why does it matter?
A monoclonal protein is an abnormal protein produced when a single group of plasma cells multiplies uncontrollably and produces identical copies of the same antibody. While our immune system normally produces many different antibodies, finding a large amount of one identical protein can signal conditions like multiple myeloma, Waldenstrom's macroglobulinemia, or other blood disorders. Detecting these proteins early is crucial for diagnosis and treatment planning.
What does it mean if monoclonal protein is detected?
If monoclonal protein is detected, it means your body is producing an abnormal amount of one specific protein type. This doesn't automatically mean cancer, as some people have a benign condition called MGUS (monoclonal gammopathy of undetermined significance) that requires monitoring but no treatment. However, it does require follow-up testing and regular monitoring to determine the cause and whether treatment is needed.
What causes abnormal immunofixation results?
Abnormal results are most commonly caused by plasma cell disorders like multiple myeloma, Waldenstrom's macroglobulinemia, or other lymphomas and leukemias. They can also result from MGUS, a usually benign condition, or chronic inflammatory conditions and autoimmune diseases. Less commonly, certain infections, kidney disease, or liver disease can cause protein abnormalities. Your doctor will consider your complete health picture to determine the cause.
How often should I retest if abnormal proteins are found?
If you have MGUS (benign protein elevation), your doctor will typically retest every 6-12 months to monitor for any changes. If you've been diagnosed with multiple myeloma or another condition and are receiving treatment, testing frequency depends on your treatment plan, often every 1-3 months during active treatment. Your healthcare provider will create a personalized monitoring schedule based on your specific diagnosis and risk factors.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at [email protected], and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at [email protected]. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email [email protected].
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email [email protected].

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

You get clinical lab reports & simplified health insights.
Save time & gas, go straight to the lab. Our doctors cover the rest.
Results start landing the next day after your lab visit.*
We don’t sell or share your data. Your time & privacy matter.
US-licensed doctors have your back if things get unclear.
No hidden fees, nice discounts for regular checkups.
Save a trip to the doctor, go directly to the lab
Instant orders, results often overnight*
Results explained in simple language
Reviewed by US licensed doctors
Fast & confidential, we never sell or share your data
No insurance needed, transparent pricing
Demo results
Immunofixation, Serum Negative
Demo results
Negative Positive
Negative

What this means

Your immunofixation test came back negative, meaning no abnormal monoclonal proteins were detected in your blood. This is a healthy result indicating normal immune system protein production and no evidence of plasma cell disorders at this time.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More complex tests, such as hormone panels, may take up to 10–15 business days due to their complexity.
Here’s how easy it is to get blood work done on your terms
Choose a checkup
Order your test Save a trip to the doctor. Your results will come with clear, friendly explanations. Takes 2 minutes
Book a lab
Book an appointment Visit any of our 4,000 nearby lab locations to have your samples collected. Book or walk-in
Choose a checkup
Get results Receive a clear, easy-to-digest health report by email & SMS within a few business days. Get answers, fast

Blood Test for Fatigue, Bone Pain, and Frequent Infections

Google
3,138 reviews
  • Pinpoint the cause of unexplained fatigue
  • Reveal hidden immune system issues
  • Clarify the source of chronic infections

1,000,000+ blood tests later, here's what our customers say

Google reviews 3138 reviews Next
Still got questions? Text our super-cool support team at 754-799-7833 to get help finding your ideal checkup.