Why Private MD Labs?
90-day money-back guarantee Lab order in minutes Save a trip to the doctor Low prices since 2005 Labs within 2 miles
Sample image
Sample report
Urine protein testing for early detection of kidney disease and multiple myeloma

Urine Test for Unexplained Fatigue and Protein Issues

Immunofixation (IFE), Urine

Google
3,138 reviews
  • Reveal hidden kidney issues effortlessly
  • Clarify the cause of unexplained fatigue
  • Detect abnormal proteins in your urine
First results as soon as overnight*

90 day happiness guarantee

We stand behind our service

Prescription & fees included

Go directly to the lab, no extra fees

Easy to understand results

With friendly doctor's notes & guidance

Fast & convenient

Lab visit as quick as 10 mins in & out

90 day happiness guarantee

We stand behind our service

Prescription & fees included

Go directly to the lab, no extra fees

Easy to understand results

With friendly doctor's notes & guidance

Fast & convenient

Lab visit as quick as 10 mins in & out

What's this test for?

This test is ideal if you're experiencing unexplained fatigue, frequent infections, bone pain, or have been told you have protein in your urine. It helps detect abnormal proteins that may indicate conditions like multiple myeloma, kidney disease, or other blood disorders. Many people use this test when routine urine tests show unusual results or when doctors want to investigate symptoms that might be related to protein abnormalities.

How should I prepare for this test?

No special preparation is typically required for this urine test. You'll need to provide a urine sample, which should be collected according to the instructions provided by the lab. Stay well-hydrated and follow any specific collection instructions given to you. If you're taking any medications or supplements, continue as prescribed unless your doctor advises otherwise.

What's included in this test?

Immunofixation (IFE), Urine

This test measures Immunofixation (IFE) in your urine, which identifies specific types of proteins your kidneys are filtering out. It's particularly valuable for detecting monoclonal proteins (abnormal proteins produced by certain blood disorders) and free light chains that appear in conditions like multiple myeloma, light chain disease, and amyloidosis. The test also reveals polyclonal protein patterns that can indicate kidney damage, infection, or inflammation, providing crucial information about your kidney function and overall health.

What happens after I get my results?
You'll receive detailed doctor notes in simple language explaining what your urine protein pattern means and whether abnormal proteins were detected. These notes include personalized recommendations on follow-up testing, dietary considerations, and whether you should consult a hematologist or nephrologist. You'll also get the standard lab report and can track your protein levels over time using our trends feature, which is especially helpful for monitoring treatment effectiveness or disease progression.
When will I get my results?
Results for immunofixation testing are typically available within 3-5 business days after the lab receives your sample. This test requires specialized analysis to identify specific protein patterns, which takes a bit longer than routine urine tests. You'll be notified as soon as your results are ready and can access them through your secure online account.
Who should consider getting this test?
This test is important for anyone with protein detected in routine urinalysis, unexplained kidney problems, or symptoms like persistent fatigue, bone pain, or frequent infections. It's especially relevant if your doctor suspects multiple myeloma, has found elevated protein levels in your blood, or if you have a family history of blood disorders. People with unexplained anemia or high calcium levels may also benefit from this testing.
What symptoms indicate I may need this test?
Common symptoms that may warrant this test include unexplained fatigue that doesn't improve with rest, bone pain especially in the back or ribs, frequent infections, unexplained weight loss, excessive thirst, or foamy urine. You might also need this test if you have numbness or tingling in your extremities, confusion, or kidney problems. These symptoms can indicate abnormal protein production that this test can identify.
What is monoclonal protein and why does it matter?
Monoclonal proteins, also called M-proteins, are abnormal proteins produced by a single clone of plasma cells in your bone marrow. Finding these proteins in your urine is significant because they can indicate conditions like multiple myeloma, a type of blood cancer, or related disorders. Unlike normal proteins, monoclonal proteins serve no useful function and can damage your kidneys, making early detection important for treatment and monitoring.
What do abnormal results mean?
Abnormal results showing monoclonal proteins may indicate conditions like multiple myeloma, light chain disease, or amyloidosis that require further evaluation by a specialist. Increased polyclonal proteins might suggest kidney damage, chronic infection, or inflammatory conditions. Not all abnormal results mean cancer—some people have benign conditions that produce unusual proteins. Your doctor will consider your symptoms, medical history, and other test results to determine the significance.
How often should I retest if results are abnormal?
If monoclonal proteins are detected, your doctor will likely recommend retesting every 3-6 months to monitor for progression, especially if you have a condition called MGUS (monoclonal gammopathy of undetermined significance). For diagnosed multiple myeloma or related conditions, testing frequency depends on your treatment plan and disease activity. If you're being treated for these conditions, your oncologist will determine the appropriate monitoring schedule based on your individual situation.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at [email protected], and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at [email protected]. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email [email protected].
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email [email protected].

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

You get clinical lab reports & simplified health insights.
Save time & gas, go straight to the lab. Our doctors cover the rest.
Results start landing the next day after your lab visit.*
We don’t sell or share your data. Your time & privacy matter.
US-licensed doctors have your back if things get unclear.
No hidden fees, nice discounts for regular checkups.
Save a trip to the doctor, go directly to the lab
Instant orders, results often overnight*
Results explained in simple language
Reviewed by US licensed doctors
Fast & confidential, we never sell or share your data
No insurance needed, transparent pricing
Demo results
Monoclonal Protein (M-Protein) Not Detected
Demo results
Not Detected Detected
Not Detected

What this means

No monoclonal proteins were detected in your urine, which is the normal and expected result. This means there are no signs of abnormal protein production that could indicate multiple myeloma or related blood disorders.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More complex tests, such as hormone panels, may take up to 10–15 business days due to their complexity.
Here’s how easy it is to get blood work done on your terms
Choose a checkup
Order your test Save a trip to the doctor. Your results will come with clear, friendly explanations. Takes 2 minutes
Book a lab
Book an appointment Visit any of our 4,000 nearby lab locations to have your samples collected. Book or walk-in
Choose a checkup
Get results Receive a clear, easy-to-digest health report by email & SMS within a few business days. Get answers, fast

Urine Test for Unexplained Fatigue and Protein Issues

Google
3,138 reviews
  • Reveal hidden kidney issues effortlessly
  • Clarify the cause of unexplained fatigue
  • Detect abnormal proteins in your urine

1,000,000+ blood tests later, here's what our customers say

Google reviews 3138 reviews Next
Still got questions? Text our super-cool support team at 754-799-7833 to get help finding your ideal checkup.