We stand behind our service
Go directly to the lab, no extra fees
With friendly doctor's notes & guidance
Lab visit as quick as 10 mins in & out
We stand behind our service
Go directly to the lab, no extra fees
With friendly doctor's notes & guidance
Lab visit as quick as 10 mins in & out
This test is ideal if you're experiencing unexplained skin blistering, rashes that don't heal, or symptoms that suggest autoimmune conditions affecting your skin and connective tissues. It helps identify antibodies related to autoimmune blistering diseases, connective tissue disorders, and vasculitides that may be causing persistent skin problems or systemic symptoms. Many people use this test when standard skin treatments haven't worked and doctors suspect an underlying autoimmune process.
No special preparation is typically required for this blood test. You can eat and drink normally before your appointment and continue taking your regular medications unless your doctor specifically instructs otherwise. It's helpful to inform the lab if you're currently on immunosuppressive medications or have recently received treatments that might affect antibody levels, as this context can help with result interpretation.
This specialized test uses indirect immunofluorescence to detect circulating antibodies in your blood, including anti-epithelial cell surface antibodies, anti-basement membrane antibodies, anti-nuclear antibodies, and antineutrophil cytoplasmic antibodies. These antibodies are markers for autoimmune blistering diseases like pemphigus and bullous pemphigoid, connective tissue disorders like lupus and scleroderma, and various types of vasculitis. Together, these measurements help diagnose and monitor autoimmune conditions that affect your skin, blood vessels, and connective tissues.
What this means
Your test came back negative, meaning no anti-epithelial cell surface antibodies were detected in your blood. This is the expected and healthy result, suggesting no active autoimmune blistering disease affecting the connections between skin cells.
Recommended actions
Continue monitoring any skin symptoms and report new blistering to your doctor
Maintain good skin care practices and protect skin from excessive friction
If you develop unexplained blisters or sores, consider retesting
Follow up with your dermatologist if symptoms persist despite negative results