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HLA genetic testing for autoimmune conditions and unexplained immune system symptoms

HLA Genetic Test for Autoimmune Risk and Immune Health

HLA DRB1,DQB1 Low Resolution

Google
3,138 reviews
  • Pinpoint genetic factors affecting your immune system
  • Reveal potential autoimmune conditions effortlessly
  • Clarify the cause of unexplained symptoms
First results as soon as overnight*

90 day happiness guarantee

We stand behind our service

Prescription & fees included

Go directly to the lab, no extra fees

Easy to understand results

With friendly doctor's notes & guidance

Fast & convenient

Lab visit as quick as 10 mins in & out

90 day happiness guarantee

We stand behind our service

Prescription & fees included

Go directly to the lab, no extra fees

Easy to understand results

With friendly doctor's notes & guidance

Fast & convenient

Lab visit as quick as 10 mins in & out

What's this test for?

This test is ideal if you're experiencing unexplained symptoms that might be related to autoimmune conditions or immune system problems. It helps identify genetic markers that can reveal your susceptibility to certain autoimmune diseases, allergies, or complications from infections. Many people use this test when they have persistent symptoms without clear answers, have a family history of autoimmune conditions, or need information for organ transplant compatibility.

How should I prepare for this test?

No special preparation is needed for this genetic test. You don't need to fast or avoid any foods or medications, since the test analyzes your DNA rather than substances in your blood that change throughout the day. You can take this test at any time that's convenient for you.

What's included in this test?

HLA DRB1,DQB1 Low Resolution

This test analyzes your HLA DRB1 and DQB1 genes at low resolution, which are key genetic markers that control how your immune system recognizes what belongs in your body and what doesn't. These specific genes are strongly linked to autoimmune conditions like rheumatoid arthritis, celiac disease, type 1 diabetes, and multiple sclerosis. Understanding your HLA type provides valuable insights into your genetic predisposition to certain immune-related conditions and can guide your healthcare decisions.

What happens after I get my results?
You'll receive detailed doctor notes in simple language explaining what your HLA genetic markers mean for your immune system and disease risk. These notes include personalized guidance on monitoring specific symptoms, lifestyle considerations, and whether you should follow up with a specialist like a rheumatologist or immunologist. Along with your standard lab report, you can use our records to share important genetic information with healthcare providers for ongoing care and future medical decisions.
When will I get my results?
Since HLA genetic testing involves specialized analysis of your DNA, results typically take longer than standard blood tests. Most labs return HLA typing results within 7-14 business days. Your results will include detailed genetic information that remains relevant throughout your lifetime, as your HLA type doesn't change.
Who should consider getting this test?
This test is particularly valuable for people with a family history of autoimmune diseases, those experiencing unexplained symptoms like chronic joint pain or digestive issues, and individuals being evaluated for organ transplant compatibility. It's also important if your doctor suspects an autoimmune condition and wants to assess your genetic risk factors, or if you have chronic infections that aren't responding as expected to treatment.
What symptoms indicate I may need this test?
Common symptoms that might warrant HLA testing include persistent unexplained joint pain or swelling, chronic fatigue that doesn't improve with rest, recurring digestive issues like bloating or diarrhea, and skin rashes without clear cause. You might also consider this test if you have numbness or tingling in your extremities, unexplained fevers, or if multiple family members have been diagnosed with autoimmune conditions.
What is HLA typing and why does it matter?
HLA (Human Leukocyte Antigen) typing identifies specific genetic markers that act like your immune system's identification system. These markers help your body distinguish between your own cells and foreign invaders like viruses or bacteria. Certain HLA types are strongly associated with increased risk for specific autoimmune diseases, making this information valuable for early detection, preventive care, and understanding your health risks.
Can I reduce my risk if I have certain HLA markers?
While you can't change your genetic HLA type, knowing your markers allows you to take proactive steps to reduce your risk of developing associated conditions. Maintaining a healthy diet rich in anti-inflammatory foods, managing stress through meditation or yoga, getting regular exercise, and avoiding smoking can all help support immune system balance. Regular monitoring with your healthcare provider allows for early intervention if symptoms develop.
What should I do if my results show high-risk HLA markers?
If your results indicate HLA markers associated with certain autoimmune conditions, don't panic - having these markers doesn't mean you'll definitely develop disease. Work with your doctor to create a monitoring plan for early symptoms, maintain regular health screenings, adopt an anti-inflammatory lifestyle with whole foods and regular exercise, and stay informed about early warning signs of associated conditions. Early awareness gives you the power to take preventive action.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at [email protected], and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at [email protected]. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email [email protected].
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email [email protected].

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

You get clinical lab reports & simplified health insights.
Save time & gas, go straight to the lab. Our doctors cover the rest.
Results start landing the next day after your lab visit.*
We don’t sell or share your data. Your time & privacy matter.
US-licensed doctors have your back if things get unclear.
No hidden fees, nice discounts for regular checkups.
Save a trip to the doctor, go directly to the lab
Instant orders, results often overnight*
Results explained in simple language
Reviewed by US licensed doctors
Fast & confidential, we never sell or share your data
No insurance needed, transparent pricing
Demo results
HLA DRB1*03:01 Allele Detected
Demo results
Not Detected Detected
Detected

What this means

Your test detected the HLA DRB1*03:01 allele, which is associated with increased genetic susceptibility to certain autoimmune conditions including type 1 diabetes and celiac disease. Having this marker doesn't mean you will develop these conditions, but it provides valuable information for monitoring and preventive care.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More complex tests, such as hormone panels, may take up to 10–15 business days due to their complexity.
Here’s how easy it is to get blood work done on your terms
Choose a checkup
Order your test Save a trip to the doctor. Your results will come with clear, friendly explanations. Takes 2 minutes
Book a lab
Book an appointment Visit any of our 4,000 nearby lab locations to have your samples collected. Book or walk-in
Choose a checkup
Get results Receive a clear, easy-to-digest health report by email & SMS within a few business days. Get answers, fast

HLA Genetic Test for Autoimmune Risk and Immune Health

Google
3,138 reviews
  • Pinpoint genetic factors affecting your immune system
  • Reveal potential autoimmune conditions effortlessly
  • Clarify the cause of unexplained symptoms

1,000,000+ blood tests later, here's what our customers say

Google reviews 3138 reviews Next
Still got questions? Text our super-cool support team at 754-799-7833 to get help finding your ideal checkup.