What happens after I get my results?

You'll receive detailed doctor notes in simple language explaining whether the HLA-B27 antigen was detected and what that means for your joint symptoms and autoimmune risk. The notes include personalized recommendations on managing inflammation, when to see a rheumatologist, and lifestyle modifications to support joint health. Along with your standard lab report, you can track this result over time, which is especially helpful if you develop new symptoms or need to monitor treatment progress.

When will I get my results?

Most HLA-B27 antigen test results are available within 3-5 business days after your blood sample reaches the lab. You'll receive an email notification when your results are ready to view in your secure online account, complete with doctor notes explaining what your results mean.

Who should consider getting this test?

This test is particularly important for people experiencing chronic lower back pain or stiffness that lasts more than three months, especially if it improves with exercise and worsens with rest. It's also valuable for those with unexplained eye inflammation, heel pain, or a family history of ankylosing spondylitis or reactive arthritis. Anyone whose doctor suspects an autoimmune cause for their joint symptoms should consider this screening.

What symptoms indicate I may need this test?

Common symptoms include chronic lower back pain and stiffness that's worse in the morning or after periods of rest, reduced flexibility in your spine, pain in your hips or buttocks, and heel pain. You might also experience eye inflammation, fatigue, or pain that improves with movement and exercise rather than rest, which is unusual for typical back pain.

What does a positive HLA-B27 result mean?

A positive result means you carry the HLA-B27 antigen, which increases your risk for certain autoimmune conditions like ankylosing spondylitis and reactive arthritis. However, it's important to know that only about 2-8% of people with HLA-B27 actually develop these conditions. Your doctor will consider your symptoms, medical history, and other tests to determine if you have an active autoimmune condition or just carry the genetic marker.

How can I naturally support my joint health if I have HLA-B27?

Regular low-impact exercise like swimming, yoga, and stretching helps maintain flexibility and reduce stiffness. An anti-inflammatory diet rich in omega-3 fatty acids from fish, colorful vegetables, and whole grains can help manage inflammation. Getting adequate sleep, managing stress, maintaining good posture, and avoiding smoking are also important for protecting your joints and spine.

How often should I monitor my condition if I'm HLA-B27 positive?

If you test positive but have no symptoms, annual check-ups with your doctor are typically sufficient to monitor for any developing issues. If you have symptoms or a diagnosed condition like ankylosing spondylitis, your rheumatologist will likely want to see you every 3-6 months to track disease progression and adjust treatment. The HLA-B27 test itself doesn't need to be repeated, as your genetic status doesn't change.