What's this test for?

This test is ideal if you're experiencing recurring autoimmune symptoms, unexplained allergic reactions, or if you have a family history of autoimmune conditions like celiac disease or ankylosing spondylitis. It helps identify specific genetic markers (HLA-B antigens) that influence how your immune system responds to infections, allergens, and your own tissues. Many people use this test to understand their genetic predisposition to certain autoimmune disorders or to help explain chronic inflammatory symptoms.

What happens after I get my results?

You'll receive detailed doctor notes in simple language explaining what your HLA-B genetic markers mean for your immune system and disease risk. These notes include personalized recommendations about which autoimmune conditions to monitor, lifestyle adjustments to support immune health, and whether you should consult with a rheumatologist or immunologist. You'll also get the standard lab report and can reference your HLA type for future medical decisions, transplant compatibility, or medication sensitivity assessments.

What's included in this test?

This test measures HLA B Low Resolution markers. This test identifies your HLA-B genetic markers, which are part of your immune system's identification system. These markers determine how your body recognizes foreign substances versus your own cells, affecting your susceptibility to autoimmune diseases, allergic reactions, and certain infections. Understanding your HLA-B type provides valuable insights into your genetic predisposition for conditions like psoriatic arthritis, reactive arthritis, and other immune-related disorders.

Who should consider getting this test?

This test is important for people with unexplained joint pain, chronic inflammation, or recurring uveitis (eye inflammation). It's also valuable if you have a family history of autoimmune diseases like ankylosing spondylitis or psoriatic arthritis, are experiencing chronic allergic symptoms without clear cause, or if your doctor suspects an HLA-associated condition. Those considering organ transplantation or who need pharmacogenetic testing for certain medications may also benefit from knowing their HLA type.

What symptoms indicate I may need this test?

Common symptoms include chronic lower back pain or stiffness (especially in the morning), recurring joint inflammation or swelling, unexplained eye inflammation or redness, persistent skin rashes like psoriasis, or chronic digestive issues. You may also consider this test if you experience frequent infections, severe drug reactions to certain medications, or have family members diagnosed with HLA-associated autoimmune conditions.

What is HLA-B and why does it matter?

HLA-B is a gene that produces proteins on the surface of your cells, acting like an identification badge that helps your immune system distinguish between your own cells and foreign invaders. Certain HLA-B variants are strongly associated with autoimmune diseases where the immune system mistakenly attacks healthy tissue. Knowing your HLA-B type can help predict disease risk, guide treatment decisions, and explain why you might be experiencing certain immune-related symptoms.

How can I support my immune system if I have certain HLA-B markers?

Focus on reducing inflammation through an anti-inflammatory diet rich in omega-3 fatty acids, colorful vegetables, and whole foods while limiting processed foods and refined sugars. Regular moderate exercise, stress management through meditation or yoga, and prioritizing quality sleep all help regulate immune function. Avoiding smoking and excessive alcohol, maintaining a healthy weight, and staying up-to-date with vaccinations also support balanced immune response regardless of your genetic markers.

What does a positive HLA-B27 result mean?

If you test positive for HLA-B27 (a common variant), it means you carry a genetic marker associated with increased risk for certain autoimmune conditions like ankylosing spondylitis and reactive arthritis. However, having this marker doesn't mean you'll definitely develop these conditions—many people with HLA-B27 remain healthy. It simply means your immune system may be more prone to inflammatory responses, and you should be aware of warning signs to catch any issues early.

Can my HLA-B type change over time?

No, your HLA-B type is determined by your genes and remains constant throughout your life. You're born with your specific HLA markers inherited from your parents, and they never change. This is why HLA testing only needs to be done once—your results will always be the same and can be referenced for future medical decisions, family planning considerations, or transplant compatibility assessments.

What should I do if my HLA-B results indicate increased disease risk?

First, remember that having risk markers doesn't mean you'll develop disease—it simply means increased vigilance is beneficial. Work with your doctor to monitor for early symptoms of associated conditions through regular check-ups. Focus on controllable factors like maintaining a healthy lifestyle, managing stress, avoiding smoking, and staying physically active. If you develop symptoms like persistent joint pain or inflammation, seek medical attention promptly for early intervention, which significantly improves outcomes.

Getting your blood test with us is easy, private & backed by the power of science.Long story short: In the test options, use the filters or search box to narrow your choices and find the test you want. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy! If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

How do I know which test to get?

In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option. Just text or call us at 754-799-7833, email us at support@privatemdlabs.com, and we'll gladly help you. We've got your back and reply quickly.

When will my lab results be available?

Most test results will be available within 1–3 business days. Once they're ready, we'll send an email and text message to let you know. After your blood draw, just hang tight and don't worry – we'll keep you updated and in the loop! If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com, and we'll gladly help you.

Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?

Absolutely! We totally understand that errors can happen. No worries, we're here to help you. Just reach out to us via text at 754-799-7833 or shoot us an email at support@privatemdlabs.com. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you. There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out. Our lab requires an address to be listed to generate an order.

Do you accept health insurance?

Only HSA & FSA is accepted. Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts. This policy applies to all insurance companies, including federal health insurance programs like Medicare. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com.

Can I cancel my order?

Yes. We get it – sometimes your needs change. As long as your samples haven’t been collected yet, we’re happy to help you cancel your order. If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com. You can read more about our cancellation policy here.

How can I find a lab location near me?

During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp). Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym. If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

HLA-B Genetic Test - Autoimmune & Immune Response

Getting your blood test with us is easy, private & backed by the power of science.

Long story short:

In the test options, use the filters or search box to narrow your choices and find the test you want.
If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!

754-799-7833

[email protected]

Genetic Test for Autoimmune Disease Risk and Joint Pain

HLA B Low Resolution

90 day happiness guarantee

Prescription & fees included

Easy to understand results

Fast & convenient

90 day happiness guarantee

Prescription & fees included

Easy to understand results

Fast & convenient

What's this test for?

What's included in this test?

What happens after I get my results?

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

Genetic Test for Autoimmune Disease Risk and Joint Pain

90 day happiness guarantee

Prescription & fees included

Easy to understand results

Fast & convenient

1,000,000+ blood tests later, here's what our customers say