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We stand behind our service
Go directly to the lab, no extra fees
With friendly doctor's notes & guidance
Lab visit as quick as 10 mins in & out
This test is essential if you've received a bone marrow transplant from a donor of the opposite biological sex. It helps verify that your body is successfully producing blood cells from the donated marrow rather than your original cells, which is crucial for transplant success. Doctors use this test to detect early signs of transplant rejection or relapse, allowing for timely intervention if needed.
No special preparation is typically required for this test, as it's a standard blood draw that analyzes your cellular DNA. However, your transplant team may have specific timing requirements based on your treatment schedule and when they need to monitor engraftment levels. Always follow any instructions provided by your oncologist or transplant coordinator, and inform the lab if you're taking any immunosuppressive medications or have recently received blood transfusions.
This test measures FISH X/Y (Fluorescence In Situ Hybridization for X and Y chromosomes), which identifies whether blood cells contain XX (female) or XY (male) chromosome patterns. This analysis is specifically designed for patients who received bone marrow from a donor of the opposite sex, making it possible to distinguish between your original cells and the donor's cells. By tracking the ratio of donor versus recipient cells, your medical team can assess how well the transplanted marrow has engrafted and whether your body is producing healthy blood cells from the new marrow.
What this means
Your test shows 78% of your blood cells are from the donor, which indicates good engraftment but is slightly below the optimal range for this stage of recovery. While this is encouraging progress, your transplant team will want to monitor this closely to ensure the percentage continues to increase or stabilize rather than decrease.
Recommended actions
Follow your transplant team's immunosuppression medication schedule precisely
Attend all scheduled follow-up appointments to monitor engraftment trends
Report any new symptoms like fatigue, fever, or unusual bruising immediately
Retest chimerism levels as recommended by your oncologist, typically in 2-4 weeks