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Estradiol

Insights Insights

Your blood test results indicate that your estradiol levels are high. Estradiol is a form of estrogen, which plays a crucial role in various bodily functions. While it's normal for estrogen levels to fluctuate, persistently high levels may have implications for your health. Research shows that elevated estradiol levels can be associated with a range of symptoms and conditions. These can include mood swings, breast tenderness, weight gain, and even an increased risk for certain types of cancers. It's recommended that you discuss these results with your healthcare provider, who can provide further guidance and determine the most appropriate course of action. They may suggest additional tests or evaluations to better understand the underlying cause of the elevated estradiol levels. They can also discuss potential treatment options if necessary. Please note that in some cases, high estradiol levels may be a result of hormone replacement therapy (HRT) or testosterone replacement therapy (TRT), which are often used to address hormonal imbalances. If you are currently undergoing either of these therapies, it's important to consult with your healthcare provider to ensure that your treatment plan is appropriately balanced. Remember, your healthcare provider has access to your complete medical history and can provide personalized advice based on your specific situation.

Estradiol
high
Desirable < 39 High
90 pg/mL

Note: Reference range established on post-pubertal patient population. No pre-pubertal reference range established using this assay. For any patients for whom low Estradiol levels are anticipated (e.g. males, pre-pubertal children and hypogonadal/post-menopausal females), the Quest Diagnostics Nichols Institute Estradiol, Ultrasensitive, LCMSMS assay is recommended (order code 30289). Please note: patients being treated with the drug fulvestrant (Faslodex(R)) have demonstrated significant interference in immunoassay methods for estradiol measurement. The cross reactivity could lead to falsely elevated estradiol test results leading to an inappropriate clinical assessment of estrogen status. Quest Diagnostics order code 30289-Estradiol, Ultrasensitive LC/MS/MS demonstrates negligible cross reactivity with fulvestrant.

Estriol

Insights Insights

Your estriol serum levels are within the normal range for your age and sex. Research shows that estriol is a hormone that is primarily produced during pregnancy and can be used to monitor fetal health. In non-pregnant individuals, estriol levels can also be used to indicate risk for certain types of cancer. However, in your case, your levels are normal and do not suggest any immediate concerns. It's recommended that you continue to monitor your levels as part of your routine blood work.

Estriol, Serum
good
<0.10 ng/mL

Note: Reference Range: ADULTS: < OR = 0.18 This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Estrogens

Insights Insights

Your estrogen levels are high, which means they are above the normal range for your age and sex. This may be due to a variety of factors, including certain medications or medical conditions. It's recommended that you follow up with your healthcare provider to determine the cause of the high estrogen levels and discuss any necessary treatment options.

Estrogens, Total, IA
high
Desirable < 404 High
688 pg/mL
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Sample report
Comprehensive estrogen testing for women with mood swings, irregular periods, and hormonal imbalances

Blood Test for Irregular Periods and Hormone Imbalance

Estrogen Testing, Comprehensive Panel

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  • Pinpoint the cause of hormonal imbalances
  • Reveal factors affecting your mood swings
  • Clarify the reasons behind irregular periods
First results as soon as overnight*

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Prescription & fees included

Go directly to the lab, no extra fees

Easy to understand results

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Lab visit as quick as 10 mins in & out

90 day happiness guarantee

We stand behind our service

Prescription & fees included

Go directly to the lab, no extra fees

Easy to understand results

With friendly doctor's notes & guidance

Fast & convenient

Lab visit as quick as 10 mins in & out

What's this test for?

This test is ideal if you're experiencing irregular periods, unexplained mood swings, fertility issues, or symptoms that suggest hormonal imbalance. It measures all three forms of estrogen to help identify what's causing your hormonal symptoms and whether your estrogen levels are affecting your menstrual cycle, mood, or overall well-being. Many women use this test when they suspect hormone-related problems but want concrete answers.

How should I prepare for this test?

No biotin: 72 hours

You should stop taking any biotin supplements (also called vitamin B7, B8, vitamin H, or coenzyme R) at least 72 hours before your blood draw, as high-dose biotin can interfere with some tests in this panel. Otherwise, no special preparation like fasting is typically required. You can take this test at any point in your menstrual cycle, though your doctor may recommend specific timing depending on what they're evaluating.

What's included in this test?

Estrogen, Total Estriol, Serum Estradiol

This comprehensive panel evaluates all three forms of estrogen that play different roles in your body. Estradiol is the primary estrogen that regulates your menstrual cycle and affects mood, energy, and bone health. Estriol is particularly important during pregnancy, while estrone becomes more significant after menopause. Together, these measurements provide a complete picture of your hormonal balance and help identify the specific type of estrogen imbalance that may be causing your symptoms.

What happens after I get my results?
You'll receive detailed doctor notes in simple language explaining what your estrogen levels mean for your menstrual cycle, mood, and overall hormonal health. These notes include personalized recommendations like lifestyle changes, supplement suggestions, or whether you should consider hormone therapy or further evaluation. You'll also get the standard lab report and can track your estrogen levels over time using our trends feature to see how your interventions are working.
Who should consider getting this test?
This test is ideal for women experiencing irregular or absent periods, unexplained fertility issues, or abnormal vaginal bleeding. It's also helpful for those going through perimenopause or menopause, women with severe mood swings or depression that may be hormone-related, and anyone wanting to understand their overall estrogen balance. If you're already on hormone therapy, this test can help monitor whether your treatment is working effectively.
What symptoms indicate I may need this test?
Common symptoms include irregular periods, very heavy or very light bleeding, difficulty getting pregnant, unexplained mood changes or depression, hot flashes or night sweats, and changes in libido. You might also experience vaginal dryness, bone loss concerns, persistent fatigue, or weight changes that don't respond to diet and exercise. If you're having multiple symptoms that seem hormone-related, this comprehensive estrogen panel can help identify the cause.
How can I naturally support healthy estrogen levels?
Maintain a healthy weight through balanced nutrition and regular exercise, as body fat can affect estrogen production. Include fiber-rich foods, cruciferous vegetables like broccoli and cauliflower, and flaxseeds which help with estrogen metabolism. Reduce alcohol consumption and manage stress through yoga, meditation, or adequate sleep. Limit exposure to endocrine disruptors found in plastics and certain personal care products.
What is estrogen and why does it matter?
Estrogen is the primary female sex hormone that regulates your menstrual cycle, supports bone health, affects mood and brain function, and influences your skin, hair, and metabolism. Your body produces three types: estradiol (most potent, active during reproductive years), estriol (dominant during pregnancy), and estrone (primary estrogen after menopause). Balanced estrogen levels are essential for reproductive health, emotional well-being, and long-term health of your bones and heart.
What does high estrogen mean?
High estrogen, also called estrogen dominance, can cause heavy or irregular periods, breast tenderness, bloating, mood swings, and weight gain especially around the hips and thighs. It may result from excess body fat, certain medications, stress, liver problems that affect hormone metabolism, or an imbalance with progesterone. Long-term elevated estrogen may increase risks for certain conditions, so it's important to identify and address the underlying cause.
What does low estrogen mean?
Low estrogen can cause irregular or absent periods, hot flashes, night sweats, vaginal dryness, mood changes, difficulty concentrating, and decreased bone density over time. This commonly occurs during menopause but can also result from excessive exercise, very low body weight, ovarian problems, or certain medical treatments. Low estrogen affects not just reproductive health but also bone strength, heart health, and cognitive function, making proper diagnosis and management important.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at [email protected], and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at [email protected]. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email [email protected].
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email [email protected].

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.

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Demo results
Estradiol 18 pg/mL
Demo results
Low Optimal 30 - 400 High
18 pg/mL

What this means

Your estradiol levels are below the optimal range, which may contribute to irregular periods, mood changes, low energy, or difficulty with fertility. Low estradiol is common during certain phases of your cycle, perimenopause, or due to factors like stress, excessive exercise, or very low body weight.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More complex tests, such as hormone panels, may take up to 10–15 business days due to their complexity.
Here’s how easy it is to get blood work done on your terms
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Order your test Save a trip to the doctor. Your results will come with clear, friendly explanations. Takes 2 minutes
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Get results Receive a clear, easy-to-digest health report by email & SMS within a few business days. Get answers, fast

Blood Test for Irregular Periods and Hormone Imbalance

Google
3,138 reviews
  • Pinpoint the cause of hormonal imbalances
  • Reveal factors affecting your mood swings
  • Clarify the reasons behind irregular periods

1,000,000+ blood tests later, here's what our customers say

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Still got questions? Text our super-cool support team at 754-799-7833 to get help finding your ideal checkup.