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CCP antibody test for early detection of rheumatoid arthritis and joint inflammation

Blood Test for Joint Pain and Arthritis Symptoms

Cyclic Citrullinated Peptide (CCP) Antibody (IgG)

Google
3,138 reviews
  • Pinpoint the cause of joint pain
  • Reveal early signs of rheumatoid arthritis
  • Clarify unexplained inflammation issues
First results as soon as overnight*

90 day happiness guarantee

We stand behind our service

Prescription & fees included

Go directly to the lab, no extra fees

Easy to understand results

With friendly doctor's notes & guidance

Fast & convenient

Lab visit as quick as 10 mins in & out

90 day happiness guarantee

We stand behind our service

Prescription & fees included

Go directly to the lab, no extra fees

Easy to understand results

With friendly doctor's notes & guidance

Fast & convenient

Lab visit as quick as 10 mins in & out

What's this test for?

This test is ideal if you're experiencing persistent joint pain, stiffness (especially in the morning), or swelling that doesn't seem to go away. It helps detect rheumatoid arthritis in its early stages, often before significant joint damage occurs, by identifying specific antibodies your immune system produces when attacking your own tissues. Many people use this test when they have unexplained joint inflammation or a family history of autoimmune conditions and want a definitive answer.

What's included in this test?

Cyclic Citrullinated Peptide (CCP) Antibody (IgG)

This test measures Cyclic Citrullinated Peptide (CCP) IgG antibodies, which are highly specific markers for rheumatoid arthritis. Approximately 70% of people with rheumatoid arthritis test positive for these antibodies, while only about 2% of healthy individuals show positive results, making it one of the most accurate tests for distinguishing rheumatoid arthritis from other inflammatory conditions. This biomarker is particularly valuable for early diagnosis, often detecting the disease before significant symptoms appear or joint damage occurs.

What happens after I get my results?

You'll receive detailed doctor notes in simple language explaining what your CCP antibody levels mean for your joint health and autoimmune status. These notes include personalized recommendations like anti-inflammatory dietary changes, joint-protective exercises, or whether you should consult a rheumatologist for further evaluation. You'll also get the standard lab report and can track your antibody levels over time using our trends feature, which is especially helpful if you're monitoring disease progression or treatment effectiveness.

Who should consider getting this test?
This test is important for anyone experiencing persistent joint pain, morning stiffness lasting more than 30 minutes, or swelling in multiple joints, especially the hands, wrists, or feet. It's also recommended if you have a family history of rheumatoid arthritis, have been experiencing unexplained fatigue along with joint symptoms, or if your doctor suspects an autoimmune condition. Early detection can help prevent irreversible joint damage and improve long-term outcomes.
What symptoms indicate I may need this test?
Common symptoms include joint pain and swelling that affects both sides of your body (like both wrists or both knees), morning stiffness that lasts for hours, persistent fatigue and low energy, or joints that feel warm to the touch. You may also notice reduced range of motion, difficulty gripping objects, or general feelings of being unwell. These symptoms often come and go in the beginning but tend to worsen over time without treatment.
What does a positive CCP antibody result mean?
A positive result means CCP antibodies were detected in your blood, which strongly suggests rheumatoid arthritis or a high risk of developing it. Because these antibodies are highly specific to rheumatoid arthritis, a positive test is a significant finding that warrants follow-up with a rheumatologist. Early intervention with disease-modifying treatments can slow joint damage and preserve mobility, so catching this early is important for your long-term quality of life.
What does a negative CCP antibody result mean?
A negative result means no CCP antibodies were detected, which makes rheumatoid arthritis less likely but doesn't completely rule it out. About 30% of people with rheumatoid arthritis are CCP-negative, so your doctor may recommend additional tests like rheumatoid factor or inflammatory markers if your symptoms continue. A negative result could also indicate your joint symptoms are caused by another condition like osteoarthritis, injury, or a different autoimmune disorder.
How can I naturally support my joint health?
Focus on an anti-inflammatory diet rich in omega-3 fatty acids from fish, walnuts, and flaxseeds, while reducing processed foods and sugar. Regular low-impact exercise like swimming, walking, or yoga helps maintain joint flexibility and strength without causing additional stress. Managing stress through meditation or deep breathing, maintaining a healthy weight, and ensuring adequate sleep all support your immune system and reduce inflammation naturally.
What is rheumatoid arthritis and why does it matter?
Rheumatoid arthritis is an autoimmune condition where your immune system mistakenly attacks the lining of your joints, causing inflammation, pain, and eventually joint damage if untreated. Unlike regular wear-and-tear arthritis, rheumatoid arthritis typically affects multiple joints symmetrically and can also impact other organs like the heart and lungs. Early detection and treatment are crucial because they can prevent irreversible joint damage, preserve your ability to perform daily activities, and significantly improve your long-term quality of life.
How often should I retest my CCP antibody levels?
If your initial test is positive and you've been diagnosed with rheumatoid arthritis, your doctor will typically monitor your condition using inflammatory markers rather than retesting CCP antibodies, since they tend to remain positive. If your first test is negative but symptoms persist, retesting may be recommended in 6-12 months as antibodies can appear over time. Once diagnosed and stable on treatment, annual monitoring of disease activity through other markers is more common than repeating the CCP test.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at [email protected], and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at [email protected]. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email [email protected].
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email [email protected].

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

You get clinical lab reports & simplified health insights.
Save time & gas, go straight to the lab. Our doctors cover the rest.
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Save a trip to the doctor, go directly to the lab
Instant orders, results often overnight*
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Demo results
CCP (Cyclic Citrullinated Peptide) Antibody IgG Negative
Demo results
Negative Positive
Negative

What this means

Your CCP antibody test came back negative, meaning no antibodies were detected in your blood. This result makes rheumatoid arthritis less likely as the cause of your symptoms, though it doesn't completely rule it out since about 30% of people with RA are CCP-negative.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More complex tests, such as hormone panels, may take up to 10–15 business days due to their complexity.
Here’s how easy it is to get blood work done on your terms
Choose a checkup
Order your test Save a trip to the doctor. Your results will come with clear, friendly explanations. Takes 2 minutes
Book a lab
Book an appointment Visit any of our 4,000 nearby lab locations to have your samples collected. Book or walk-in
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Get results Receive a clear, easy-to-digest health report by email & SMS within a few business days. Get answers, fast

Blood Test for Joint Pain and Arthritis Symptoms

Google
3,138 reviews
  • Pinpoint the cause of joint pain
  • Reveal early signs of rheumatoid arthritis
  • Clarify unexplained inflammation issues

1,000,000+ blood tests later, here's what our customers say

Google reviews 3138 reviews Next
Still got questions? Text our super-cool support team at 754-799-7833 to get help finding your ideal checkup.