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APOE genetic testing for cardiovascular and cholesterol-related heart disease risk assessment

Genetic Test for Heart Disease Risk and Cholesterol Issues

Cardio IQ APOE Genotype

Google
3,138 reviews
  • Identifies heart disease risk genes.
  • Analyzes cholesterol-related genes.
  • Checks genetic role in heart health.
First results as soon as overnight*

90 day happiness guarantee

We stand behind our service

Prescription & fees included

Go directly to the lab, no extra fees

Easy to understand results

With friendly doctor's notes & guidance

Fast & convenient

Lab visit as quick as 10 mins in & out

90 day happiness guarantee

We stand behind our service

Prescription & fees included

Go directly to the lab, no extra fees

Easy to understand results

With friendly doctor's notes & guidance

Fast & convenient

Lab visit as quick as 10 mins in & out

What's this test for?

This test is ideal if you have a family history of heart disease, high cholesterol that doesn't respond well to treatment, or early heart attacks in your family. It identifies specific genetic variants in the APOE gene that affect how your body processes cholesterol and fats, which can significantly influence your cardiovascular risk. Many people use this test to understand why they have persistent cholesterol issues or to personalize their heart disease prevention strategy based on their genetic makeup.

How should I prepare for this test?

Since this is a genetic test, no special preparation is required. You don't need to fast or avoid any foods or medications before testing. The test analyzes your DNA, which remains constant throughout your life, so factors like diet, medication, or time of day don't affect the results.

What's included in this test?

Apoe Genotype General Guidance Guidance Statements

This test analyzes your APOE gene variants to determine which version you inherited from your parents. The APOE genotype plays a crucial role in how your body metabolizes cholesterol and responds to dietary fats, directly impacting your risk for cardiovascular disease and how you should approach heart-healthy eating. This genetic information provides lifelong guidance on the most effective personalized strategies for managing cholesterol and reducing heart disease risk.

What happens after I get my results?
You'll receive detailed doctor notes in simple language explaining what your APOE genetic variant means for your heart health and cholesterol management. These notes include personalized recommendations on the most effective dietary approaches for your genotype, whether you're more likely to benefit from specific medications, and lifestyle modifications tailored to your genetic risk profile. You'll also get the standard lab report, and this genetic information remains constant throughout your life, helping guide long-term cardiovascular prevention strategies.
When will I get my results?
Genetic testing typically takes longer than standard blood work because it involves DNA analysis. You can generally expect your APOE genotype results within 7-14 business days after the lab receives your sample. This is a one-time test that provides permanent information about your genetic makeup.
Who should consider getting this test?
This test is particularly valuable for people with a strong family history of heart disease or stroke, those with high cholesterol that doesn't improve with standard treatment, or anyone who has experienced cardiovascular events at a young age. It's also useful for people who want to take a proactive, personalized approach to heart disease prevention by understanding their genetic risk factors. Those with family members who have had early heart attacks or Alzheimer's disease may also benefit from this genetic insight.
What symptoms indicate I may need this test?
This test isn't about current symptoms but rather about understanding your genetic risk factors. You might consider it if you have persistently high cholesterol despite lifestyle changes, unexplained cardiovascular issues, or if multiple family members have had heart attacks or strokes at relatively young ages. It's also relevant if your doctor has mentioned that your cholesterol levels are difficult to manage with typical interventions.
What is APOE genotype and why does it matter?
APOE is a gene that provides instructions for making a protein involved in transporting cholesterol and other fats in your bloodstream. There are three common variants (E2, E3, and E4), and the combination you inherit from your parents influences how efficiently your body clears cholesterol, how you respond to dietary fats, and your overall cardiovascular disease risk. Knowing your APOE genotype helps you and your doctor create a more personalized and effective strategy for protecting your heart health throughout your life.
How can I manage my heart health based on my APOE genotype?
Your APOE genotype influences how your body responds to dietary changes, particularly saturated fat intake. People with certain APOE variants benefit more from low-fat diets, while others may do better with different approaches. Beyond diet, regular cardiovascular exercise, maintaining a healthy weight, not smoking, and managing stress are universally important. Your doctor may also adjust medication choices or monitoring frequency based on your genetic risk profile.
How often should I retest my APOE genotype?
You only need to take this test once in your lifetime because your genetic code doesn't change. The APOE genotype you inherit is permanent and provides ongoing guidance for your cardiovascular health management. However, while the genetic test doesn't need repeating, you should continue monitoring your cholesterol levels and other cardiovascular markers regularly to see how your personalized prevention strategies are working.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at [email protected], and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at [email protected]. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email [email protected].
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email [email protected].

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

You get clinical lab reports & simplified health insights.
Save time & gas, go straight to the lab. Our doctors cover the rest.
Results start landing the next day after your lab visit.*
We don’t sell or share your data. Your time & privacy matter.
US-licensed doctors have your back if things get unclear.
No hidden fees, nice discounts for regular checkups.
Save a trip to the doctor, go directly to the lab
Instant orders, results often overnight*
Results explained in simple language
Reviewed by US licensed doctors
Fast & confidential, we never sell or share your data
No insurance needed, transparent pricing
Demo results
APOE Genotype E3/E4
Demo results
E2 Variants E3/E3 (Most Common) E4 Variants
E3/E4

What this means

You carry one copy of the APOE4 variant, which is associated with higher cholesterol levels and increased cardiovascular disease risk compared to the most common E3/E3 genotype. This doesn't mean you will definitely develop heart disease, but it indicates you may benefit more from proactive heart-healthy lifestyle choices and closer monitoring of your cholesterol levels.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More complex tests, such as hormone panels, may take up to 10–15 business days due to their complexity.
Here’s how easy it is to get blood work done on your terms
Choose a checkup
Order your test Save a trip to the doctor. Your results will come with clear, friendly explanations. Takes 2 minutes
Book a lab
Book an appointment Visit any of our 4,000 nearby lab locations to have your samples collected. Book or walk-in
Choose a checkup
Get results Receive a clear, easy-to-digest health report by email & SMS within a few business days. Get answers, fast

Genetic Test for Heart Disease Risk and Cholesterol Issues

Google
3,138 reviews
  • Identifies heart disease risk genes.
  • Analyzes cholesterol-related genes.
  • Checks genetic role in heart health.

1,000,000+ blood tests later, here's what our customers say

Google reviews 3138 reviews Next
Still got questions? Text our super-cool support team at 754-799-7833 to get help finding your ideal checkup.