Why Private MD Labs?
90-day money-back guarantee Lab order in minutes Save a trip to the doctor Low prices since 2005 Labs within 2 miles
Sample image
Sample report
Allergy testing for those with unexplained reactions and sensitivities to common substances

Blood Test for Unexplained Allergic Reactions and Sensitivities

BasoFunction™ HRT Lys-Aspirin

Google
3,138 reviews
  • Pinpoint the cause of unexplained fatigue
  • Reveal hidden inflammation affecting your health
  • Assess your response to hormone therapy accurately
First results as soon as overnight*

90 day happiness guarantee

We stand behind our service

Prescription & fees included

Go directly to the lab, no extra fees

Easy to understand results

With friendly doctor's notes & guidance

Fast & convenient

Lab visit as quick as 10 mins in & out

90 day happiness guarantee

We stand behind our service

Prescription & fees included

Go directly to the lab, no extra fees

Easy to understand results

With friendly doctor's notes & guidance

Fast & convenient

Lab visit as quick as 10 mins in & out

What's this test for?

This test is ideal if you're experiencing unexplained allergic reactions, hives, or sensitivity to medications like aspirin or hormone therapy, but traditional skin testing isn't an option for you. It helps identify if your immune cells (basophils) are reacting abnormally to specific triggers, which can cause symptoms like flushing, itching, or inflammation. People often use this when they need answers about mysterious allergic responses but can't undergo standard allergy testing methods.

How should I prepare for this test?

If you're taking calcineurin inhibitors (immunosuppressive medications), you should stop taking them 72 hours before your blood draw. These medications can interfere with the test's ability to measure your basophil response accurately. If you have questions about stopping any medications, consult with your healthcare provider before your appointment.

What's included in this test?

BasoFunction™ HRT Lys-Aspirin

This test measures how your basophils (a type of white blood cell involved in allergic reactions) respond when challenged with specific substances like lysine-aspirin in your blood sample. It provides insights into whether your immune system is overreacting to these triggers, which can help explain unexplained allergic symptoms, drug sensitivities, or inflammatory responses. This functional test is particularly useful when traditional allergy testing methods aren't suitable or available for your situation.

What happens after I get my results?
You'll receive detailed doctor notes in simple language explaining what your basophil response means and whether your cells are reacting abnormally to the tested substance. These notes include personalized recommendations like avoiding certain triggers, considering alternative medications, or lifestyle modifications to reduce allergic responses. You'll also get the standard lab report and can track your immune response over time using our trends feature, especially helpful if you're managing chronic allergy symptoms or testing different treatments.
Who should consider getting this test?
This test is ideal for people who experience unexplained allergic reactions, chronic hives, or suspected sensitivities to aspirin or hormone replacement therapy. It's particularly useful if you can't undergo traditional skin prick testing due to skin conditions, certain medications, or other contraindications. People with a history of severe allergic reactions who need to identify specific triggers should also consider this specialized functional test.
What symptoms indicate I may need this test?
You may need this test if you experience unexplained hives, flushing, itching, or swelling after taking certain medications like aspirin or during hormone therapy. Other signs include chronic inflammatory symptoms, recurring allergic reactions without a clear cause, or if you've been advised against skin testing. This test is particularly helpful when you and your doctor suspect drug sensitivity or immune cell activation but need objective confirmation.
How can I naturally support my immune system and reduce allergic responses?
Supporting a balanced immune system involves eating anti-inflammatory foods like fatty fish, leafy greens, berries, and foods rich in quercetin like apples and onions. Managing stress through meditation, adequate sleep, and regular exercise helps regulate immune responses. Avoiding known triggers, maintaining a healthy gut microbiome with probiotics, and staying well-hydrated can also help reduce the frequency and severity of allergic reactions.
What is basophil activation and why does it matter?
Basophils are white blood cells that play a key role in allergic reactions by releasing histamine and other chemicals when they encounter substances your body perceives as threats. When basophils become overly activated, they can trigger symptoms like itching, hives, swelling, and inflammation. Understanding your basophil response helps identify what's causing your allergic symptoms and guides treatment decisions, especially when other testing methods haven't provided clear answers.
What does an abnormal basophil activation result mean?
An abnormal result means your basophils are reacting more strongly than expected to the tested substance, indicating a true allergic or sensitivity response. This can explain symptoms like hives, flushing, or inflammatory reactions you've been experiencing. The degree of activation helps your doctor understand the severity of your sensitivity and make informed decisions about avoiding triggers or adjusting medications like aspirin or hormone therapy.
How often should I retest my basophil function?
Retesting frequency depends on your specific situation and treatment plan. If you're avoiding a trigger or undergoing desensitization therapy, your doctor may recommend retesting every 6-12 months to see if your sensitivity has changed. For chronic allergy management, annual testing can help track whether your immune responses are improving with treatment. If you're testing new medications or treatments, your doctor will advise on the appropriate timing for follow-up testing.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at [email protected], and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at [email protected]. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email [email protected].
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email [email protected].

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

You get clinical lab reports & simplified health insights.
Save time & gas, go straight to the lab. Our doctors cover the rest.
Results start landing the next day after your lab visit.*
We don’t sell or share your data. Your time & privacy matter.
US-licensed doctors have your back if things get unclear.
No hidden fees, nice discounts for regular checkups.
Save a trip to the doctor, go directly to the lab
Instant orders, results often overnight*
Results explained in simple language
Reviewed by US licensed doctors
Fast & confidential, we never sell or share your data
No insurance needed, transparent pricing
Demo results
BasoFunction™ HRT Lys-Aspirin Negative
Demo results
Negative Positive
Negative

What this means

Your test came back negative, meaning your basophils did not show abnormal activation in response to lysine-aspirin. This suggests you likely do not have a hypersensitivity or allergic reaction to aspirin-related compounds, which is the expected and healthy result.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More complex tests, such as hormone panels, may take up to 10–15 business days due to their complexity.
Here’s how easy it is to get blood work done on your terms
Choose a checkup
Order your test Save a trip to the doctor. Your results will come with clear, friendly explanations. Takes 2 minutes
Book a lab
Book an appointment Visit any of our 4,000 nearby lab locations to have your samples collected. Book or walk-in
Choose a checkup
Get results Receive a clear, easy-to-digest health report by email & SMS within a few business days. Get answers, fast

Blood Test for Unexplained Allergic Reactions and Sensitivities

Google
3,138 reviews
  • Pinpoint the cause of unexplained fatigue
  • Reveal hidden inflammation affecting your health
  • Assess your response to hormone therapy accurately

1,000,000+ blood tests later, here's what our customers say

Google reviews 3138 reviews Next
Still got questions? Text our super-cool support team at 754-799-7833 to get help finding your ideal checkup.