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Go directly to the lab, no extra fees
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We stand behind our service
Go directly to the lab, no extra fees
With friendly doctor's notes & guidance
Lab visit as quick as 10 mins in & out
This test is ideal if you're taking aspirin to prevent heart attacks or strokes and want to know if it's actually working for you. Some people are aspirin-resistant, meaning their bodies don't respond to aspirin's blood-thinning effects as expected. This test helps identify whether you're getting the cardiovascular protection you need from your aspirin therapy, which is especially important if you have heart disease, have had a previous heart event, or are at high risk for blood clots.
Since this is a urine test, no special fasting is required. However, it's important to continue taking your aspirin as prescribed before testing, as the purpose is to measure how well aspirin is working in your body. Your doctor may provide specific instructions about timing, such as collecting urine at a certain time of day or after a specific duration of aspirin use. Follow any personalized guidance from your healthcare provider for the most accurate results.
This test measures 11-dehydrothromboxane B2 (11-dhTXB2) with creatinine in your urine. 11-dhTXB2 is the principal metabolite of thromboxane B2, which platelets produce when they form clots. By measuring this substance, the test reveals whether aspirin is successfully blocking platelet activity and reducing your clotting risk. The creatinine measurement helps normalize the results for accurate interpretation, giving your doctor clear insight into your body's response to aspirin therapy.
What this means
Your 11-dhTXB2 level is elevated, suggesting that aspirin may not be fully blocking platelet activity in your body. This indicates possible aspirin resistance, meaning you might not be getting the full cardiovascular protection expected from your aspirin therapy. This finding is important to discuss with your doctor to optimize your treatment plan.
Recommended actions
Discuss your results with your doctor to consider adjusting aspirin dose or adding alternative antiplatelet therapy
Ensure you're taking aspirin consistently at the same time each day as prescribed
Avoid NSAIDs like ibuprofen which can interfere with aspirin's effectiveness
Retest in 4-8 weeks after any treatment adjustments to confirm improved response