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Celiac disease screening test for individuals experiencing digestive issues and gluten sensitivity

Blood Test for Digestive Issues and Gluten Sensitivity

Anti-tTG IgA (Tissue Transglutaminase IgA)

Google
3,138 reviews
  • Screen for celiac disease
  • Monitor autoimmune response
  • Assess gut inflammation
First results as soon as overnight*

90 day happiness guarantee

We stand behind our service

Prescription & fees included

Go directly to the lab, no extra fees

Easy to understand results

With friendly doctor's notes & guidance

Fast & convenient

Lab visit as quick as 10 mins in & out

90 day happiness guarantee

We stand behind our service

Prescription & fees included

Go directly to the lab, no extra fees

Easy to understand results

With friendly doctor's notes & guidance

Fast & convenient

Lab visit as quick as 10 mins in & out

What's this test for?

This test is ideal if you're experiencing unexplained digestive issues like bloating, diarrhea, stomach pain, or weight loss after eating foods with gluten. It helps identify celiac disease, an autoimmune condition where gluten triggers your immune system to attack your small intestine. Many people use this test when they suspect gluten is causing their symptoms but want confirmation before making major dietary changes.

How should I prepare for this test?

It's crucial to continue eating foods containing gluten before this test, as avoiding gluten can lead to false negative results. Do not start a gluten-free diet until after testing, even if you suspect celiac disease. No fasting is typically required for this test, but check with your testing location for any specific requirements.

What's included in this test?

Tissue Transglutaminase (tTG) Antibody (IgA)

This test measures Tissue Transglutaminase (tTG) IgA antibodies, which are the most sensitive and specific markers for celiac disease. When you have celiac disease, your immune system produces these antibodies in response to gluten, and elevated levels strongly suggest an autoimmune reaction damaging your intestinal lining. This test helps determine if your digestive symptoms, nutrient deficiencies, or other health issues are related to gluten intolerance.

What happens after I get my results?
You'll receive detailed doctor notes in simple language explaining what your antibody levels mean and whether they indicate celiac disease or gluten sensitivity. These notes include personalized recommendations about dietary changes, whether you should eliminate gluten, and when to follow up with a gastroenterologist for further testing like an endoscopy. You'll also get the standard lab report and can track your antibody levels over time using our trends feature, which is especially helpful if you adopt a gluten-free diet and want to monitor improvement.
Who should consider getting this test?
This test is important for anyone with unexplained digestive issues, chronic diarrhea, bloating, or unexplained weight loss. It's also recommended for people with a family history of celiac disease, those with Type 1 diabetes or other autoimmune conditions, and individuals experiencing fatigue, anemia, or nutrient deficiencies that don't respond to treatment. People with skin rashes like dermatitis herpetiformis should also consider testing.
What symptoms indicate I may need this test?
Common symptoms include persistent bloating, gas, diarrhea, constipation, stomach pain, and nausea after eating gluten-containing foods. You may also experience fatigue, brain fog, headaches, unexplained weight loss, or nutrient deficiencies like low iron or vitamin D. Some people develop skin rashes, joint pain, or mouth sores. Children may show growth delays or behavioral changes.
How can I support my gut health if I have celiac disease?
The only effective treatment for celiac disease is a strict gluten-free diet, eliminating wheat, barley, rye, and contaminated oats. Focus on naturally gluten-free whole foods like fruits, vegetables, lean proteins, rice, and quinoa. Consider taking a high-quality probiotic to support gut healing and ensure adequate intake of nutrients commonly deficient in celiac disease, like iron, calcium, vitamin D, and B vitamins. Work with a dietitian experienced in celiac disease for guidance.
What does a positive tTG IgA result mean?
A positive or elevated result indicates your immune system is producing antibodies against tissue transglutaminase in response to gluten, which strongly suggests celiac disease. This means gluten is likely triggering an autoimmune reaction that damages your small intestine lining. A positive result typically requires follow-up with a gastroenterologist for an endoscopy and biopsy to confirm the diagnosis before starting a gluten-free diet.
What does a negative tTG IgA result mean?
A negative result means no significant levels of tTG IgA antibodies were detected, which usually rules out celiac disease. However, if you have IgA deficiency (which affects about 2-3% of people with celiac disease), this test may be falsely negative. If you still have symptoms despite a negative result, your doctor may recommend additional tests like total IgA levels or tTG IgG antibodies, or consider non-celiac gluten sensitivity.
How often should I retest my tTG IgA levels?
If you're diagnosed with celiac disease and start a gluten-free diet, your doctor will typically retest every 6-12 months to ensure antibody levels are decreasing and your treatment is working. It can take 6 months to 2 years for levels to normalize on a strict gluten-free diet. Once stable, annual testing helps monitor compliance and intestinal healing. If levels remain elevated, it may indicate ongoing gluten exposure.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at [email protected], and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at [email protected]. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email [email protected].
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email [email protected].

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

You get clinical lab reports & simplified health insights.
Save time & gas, go straight to the lab. Our doctors cover the rest.
Results start landing the next day after your lab visit.*
We don’t sell or share your data. Your time & privacy matter.
US-licensed doctors have your back if things get unclear.
No hidden fees, nice discounts for regular checkups.
Save a trip to the doctor, go directly to the lab
Instant orders, results often overnight*
Results explained in simple language
Reviewed by US licensed doctors
Fast & confidential, we never sell or share your data
No insurance needed, transparent pricing
Demo results
Tissue Transglutaminase (tTG) Antibody (IgA) 6.2 U/mL
Demo results
Negative < 4.0 Positive ≥ 4.0
6.2 U/mL

What this means

Your tTG IgA antibody level is elevated, which indicates your immune system is producing antibodies in response to gluten. This strongly suggests celiac disease and means gluten may be triggering inflammation and damage to your small intestine. Follow-up with a gastroenterologist is recommended to confirm the diagnosis.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More complex tests, such as hormone panels, may take up to 10–15 business days due to their complexity.
Here’s how easy it is to get blood work done on your terms
Choose a checkup
Order your test Save a trip to the doctor. Your results will come with clear, friendly explanations. Takes 2 minutes
Book a lab
Book an appointment Visit any of our 4,000 nearby lab locations to have your samples collected. Book or walk-in
Choose a checkup
Get results Receive a clear, easy-to-digest health report by email & SMS within a few business days. Get answers, fast

Blood Test for Digestive Issues and Gluten Sensitivity

Google
3,138 reviews
  • Screen for celiac disease
  • Monitor autoimmune response
  • Assess gut inflammation

1,000,000+ blood tests later, here's what our customers say

Google reviews 3138 reviews Next
Still got questions? Text our super-cool support team at 754-799-7833 to get help finding your ideal checkup.