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Anti-dsDNA test for individuals with unexplained fatigue, joint pain, and autoimmune concerns

Blood Test for Joint Pain and Autoimmune Issues

Anti-dsDNA (Double-Stranded) Antibiodies, EIA

Google
3,138 reviews
  • Pinpoint the cause of unexplained fatigue
  • Reveal underlying autoimmune issues effortlessly
  • Clarify the source of persistent joint pain
First results as soon as overnight*

90 day happiness guarantee

We stand behind our service

Prescription & fees included

Go directly to the lab, no extra fees

Easy to understand results

With friendly doctor's notes & guidance

Fast & convenient

Lab visit as quick as 10 mins in & out

90 day happiness guarantee

We stand behind our service

Prescription & fees included

Go directly to the lab, no extra fees

Easy to understand results

With friendly doctor's notes & guidance

Fast & convenient

Lab visit as quick as 10 mins in & out

What's this test for?

This test is ideal if you're experiencing unexplained fatigue, persistent joint pain, skin rashes, or swelling that won't go away. It helps detect antibodies associated with systemic lupus erythematosus (SLE) and related autoimmune conditions that can affect your joints, skin, and overall energy levels. Many people use this test when they have symptoms suggesting an autoimmune disorder and want to understand what's causing their discomfort.

How should I prepare for this test?

No special preparation is typically required for this test. You can take your regular medications and eat normally before your blood draw. However, it's always a good idea to stay well-hydrated and inform the lab if you're taking any immunosuppressive medications, as they may be relevant to interpreting your results.

What's included in this test?

Dna (Ds) Antibody

This test measures double-stranded DNA (dsDNA) antibodies, which are highly specific markers for systemic lupus erythematosus (SLE). Detecting these antibodies helps confirm active lupus and can indicate disease severity, making it essential for both diagnosis and monitoring treatment effectiveness. The presence of these antibodies can explain symptoms like joint pain, fatigue, skin rashes, and inflammation affecting multiple body systems.

What happens after I get my results?
You'll receive detailed doctor notes in simple language explaining what your antibody levels mean and how they relate to autoimmune conditions like lupus. These notes include personalized recommendations such as lifestyle adjustments, when to follow up with a rheumatologist, or what additional testing might be helpful. You'll also get the standard lab report and can track your antibody levels over time using our trends feature, which is especially useful for monitoring disease activity.
When will I get my results?
Most results are available within 1-3 business days after your blood sample reaches the lab. You'll receive an email notification as soon as your results are ready to view in your secure online account. Complex or specialty testing may occasionally take a bit longer, but you'll be kept informed throughout the process.
Who should consider getting this test?
This test is important for anyone experiencing symptoms of lupus such as unexplained fatigue, joint pain and swelling, skin rashes (especially a butterfly-shaped rash on the face), fever, or sensitivity to sunlight. It's also valuable if you've already been diagnosed with lupus and need to monitor disease activity, or if you have a family history of autoimmune conditions and are experiencing concerning symptoms.
What symptoms indicate I may need this test?
Common symptoms that may indicate the need for this test include persistent joint pain and stiffness, extreme fatigue that doesn't improve with rest, unexplained fevers, and skin rashes that worsen in sunlight. You might also experience hair loss, mouth sores, chest pain when breathing deeply, or fingers and toes that turn white or blue in the cold. These symptoms can come and go in flares, making patterns important to notice.
How can I naturally support my immune system with lupus?
Managing lupus involves protecting yourself from sun exposure with sunscreen and protective clothing, as UV light can trigger flares. Getting adequate rest, managing stress through gentle activities like tai chi or meditation, and eating an anti-inflammatory diet rich in omega-3 fatty acids can help. Avoiding smoking and limiting alcohol is important, and gentle, low-impact exercise like swimming or walking can help maintain joint flexibility without causing flares.
What is systemic lupus erythematosus and why does it matter?
Systemic lupus erythematosus (SLE) is an autoimmune disease where your immune system mistakenly attacks your own healthy tissues, causing inflammation throughout the body. It can affect your joints, skin, kidneys, heart, lungs, and brain, which is why catching it early and monitoring it matters so much. While there's no cure, proper diagnosis and treatment can help manage symptoms, prevent organ damage, and allow many people with lupus to live full, active lives.
What does a positive anti-dsDNA result mean?
A positive result means antibodies against double-stranded DNA were detected in your blood, which is highly specific for systemic lupus erythematosus (SLE). This suggests active lupus and may correlate with disease severity, particularly kidney involvement. Your doctor will interpret this result along with your symptoms, physical exam findings, and other tests to confirm the diagnosis and determine the best treatment approach.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at [email protected], and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at [email protected]. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email [email protected].
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email [email protected].

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

You get clinical lab reports & simplified health insights.
Save time & gas, go straight to the lab. Our doctors cover the rest.
Results start landing the next day after your lab visit.*
We don’t sell or share your data. Your time & privacy matter.
US-licensed doctors have your back if things get unclear.
No hidden fees, nice discounts for regular checkups.
Save a trip to the doctor, go directly to the lab
Instant orders, results often overnight*
Results explained in simple language
Reviewed by US licensed doctors
Fast & confidential, we never sell or share your data
No insurance needed, transparent pricing
Demo results
Anti-dsDNA Antibodies Negative
Demo results
Negative Positive
Negative

What this means

Your test came back negative, meaning no anti-dsDNA antibodies were detected in your blood. This is a good result and makes active systemic lupus erythematosus (SLE) less likely, though it doesn't completely rule out all autoimmune conditions.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More complex tests, such as hormone panels, may take up to 10–15 business days due to their complexity.
Here’s how easy it is to get blood work done on your terms
Choose a checkup
Order your test Save a trip to the doctor. Your results will come with clear, friendly explanations. Takes 2 minutes
Book a lab
Book an appointment Visit any of our 4,000 nearby lab locations to have your samples collected. Book or walk-in
Choose a checkup
Get results Receive a clear, easy-to-digest health report by email & SMS within a few business days. Get answers, fast

Blood Test for Joint Pain and Autoimmune Issues

Google
3,138 reviews
  • Pinpoint the cause of unexplained fatigue
  • Reveal underlying autoimmune issues effortlessly
  • Clarify the source of persistent joint pain

1,000,000+ blood tests later, here's what our customers say

Google reviews 3138 reviews Next
Still got questions? Text our super-cool support team at 754-799-7833 to get help finding your ideal checkup.