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Autoimmune screening test for individuals experiencing unexplained fatigue, joint pain, and inflammation

Autoimmune Blood Test for Fatigue, Joint Pain & Inflammation

ANA Screen IFA w/ Ref to Titer and Pattern

Google
3,141 reviews
  • Unveil autoimmune issues affecting your health
  • Clarify unexplained symptoms like fatigue or pain
  • Pinpoint specific antibodies causing your problems
First results as soon as overnight*

90 day happiness guarantee

We stand behind our service

Prescription & fees included

Go directly to the lab, no extra fees

Easy to understand results

With friendly doctor's notes & guidance

Fast & convenient

Lab visit as quick as 10 mins in & out

90 day happiness guarantee

We stand behind our service

Prescription & fees included

Go directly to the lab, no extra fees

Easy to understand results

With friendly doctor's notes & guidance

Fast & convenient

Lab visit as quick as 10 mins in & out

What's this test for?

This test is ideal if you're experiencing unexplained symptoms like chronic fatigue, joint pain, muscle aches, persistent rashes, or recurring fevers that doctors haven't been able to explain. It helps identify antinuclear antibodies (ANA) in your blood, which are markers of autoimmune conditions where your immune system mistakenly attacks your own tissues. Many people use this test when they suspect an autoimmune disease like lupus, rheumatoid arthritis, or Sjögren's syndrome might be causing their symptoms.

How should I prepare for this test?

No special preparation is required for this test. You don't need to fast, and you can take your regular medications and eat normally before your blood draw. Simply schedule your appointment and arrive ready to have a quick blood sample taken.

What's included in this test?

Ana Screen, Ifa

This test screens for antinuclear antibodies using immunofluorescence assay (IFA), which is the gold standard method for detecting these antibodies. If antibodies are found, the test provides additional information about the titer (concentration level) and pattern, which helps identify specific autoimmune conditions like lupus, scleroderma, or mixed connective tissue disease. This comprehensive approach gives your doctor important clues about what might be causing your symptoms and guides further testing if needed.

What happens after I get my results?
You'll receive detailed doctor notes in simple language explaining what your ANA test results mean and whether antibodies were detected. These notes include personalized recommendations on next steps, such as lifestyle modifications to reduce inflammation, whether additional autoimmune testing is needed, or when to consult a rheumatologist. You'll also get the standard lab report, and if your results are positive, our trends feature helps you track antibody patterns over time to monitor disease activity.
Who should consider getting this test?
This test is recommended for anyone experiencing unexplained symptoms like persistent fatigue, joint pain, skin rashes, or muscle weakness that suggest an autoimmune condition. It's especially important if you have a family history of autoimmune diseases like lupus or rheumatoid arthritis, or if your doctor suspects an autoimmune disorder based on your symptoms. Women aged 15-45 are at higher risk for many autoimmune conditions and may benefit from screening.
What symptoms indicate I may need this test?
Common symptoms that may warrant ANA testing include persistent fatigue that doesn't improve with rest, joint pain or swelling in multiple joints, unexplained fevers, skin rashes (especially on the face or sun-exposed areas), muscle weakness or pain, sensitivity to sunlight, dry eyes and mouth, or hair loss. If you're experiencing several of these symptoms together, or if they've been ongoing for weeks or months without explanation, this test can help identify whether an autoimmune process might be involved.
How can I naturally support my immune system with autoimmune concerns?
Focus on an anti-inflammatory diet rich in omega-3 fatty acids from fish, colorful fruits and vegetables, and minimize processed foods and sugar. Prioritize quality sleep of 7-9 hours nightly and manage stress through gentle activities like yoga, meditation, or tai chi. Regular low-impact exercise like swimming or walking can help reduce inflammation without overtaxing your system, and avoiding smoking and excessive alcohol supports overall immune balance.
What is ANA and why does it matter?
Antinuclear antibodies (ANA) are proteins your immune system produces that mistakenly target the nucleus of your own cells, which is a hallmark of autoimmune diseases. When present, ANA can indicate conditions like lupus, Sjögren's syndrome, scleroderma, or mixed connective tissue disease. The specific pattern and titer of ANA helps doctors narrow down which autoimmune condition might be present and guides further diagnostic testing and treatment decisions.
What does a positive ANA result mean?
A positive ANA result means that antinuclear antibodies were detected in your blood, which suggests your immune system may be reacting against your own tissues. However, a positive result doesn't automatically mean you have an autoimmune disease—some healthy people test positive, and certain medications can cause positive results. The pattern and titer level, along with your symptoms and additional testing, help your doctor determine whether an autoimmune condition is present and which one it might be.
How often should I retest my ANA levels?
If your initial ANA test is negative but symptoms persist or worsen, your doctor may recommend retesting in 3-6 months since antibodies can develop over time. If you test positive and are diagnosed with an autoimmune condition, your doctor will typically monitor disease activity through other specific tests rather than repeating ANA frequently. For those on treatment, follow-up testing schedules depend on your specific condition and how well you're responding to therapy.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at [email protected], and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at [email protected]. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email [email protected].
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email [email protected].

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

You get clinical lab reports & simplified health insights.
Save time & gas, go straight to the lab. Our doctors cover the rest.
Results start landing the next day after your lab visit.*
We don’t sell or share your data. Your time & privacy matter.
US-licensed doctors have your back if things get unclear.
No hidden fees, nice discounts for regular checkups.
Save a trip to the doctor, go directly to the lab
Instant orders, results often overnight*
Results explained in simple language
Reviewed by US licensed doctors
Fast & confidential, we never sell or share your data
No insurance needed, transparent pricing
Demo results
ANA Screen (IFA) Negative
Demo results
Negative Positive
Negative

What this means

Your ANA test came back negative, meaning no antinuclear antibodies were detected in your blood. This is the expected and healthy result, suggesting that an autoimmune condition is less likely to be causing your symptoms.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More complex tests, such as hormone panels, may take up to 10–15 business days due to their complexity.
Here’s how easy it is to get blood work done on your terms
Choose a checkup
Order your test Save a trip to the doctor. Your results will come with clear, friendly explanations. Takes 2 minutes
Book a lab
Book an appointment Visit any of our 4,000 nearby lab locations to have your samples collected. Book or walk-in
Choose a checkup
Get results Receive a clear, easy-to-digest health report by email & SMS within a few business days. Get answers, fast

Autoimmune Blood Test for Fatigue, Joint Pain & Inflammation

Google
3,141 reviews
  • Unveil autoimmune issues affecting your health
  • Clarify unexplained symptoms like fatigue or pain
  • Pinpoint specific antibodies causing your problems

1,000,000+ blood tests later, here's what our customers say

Google reviews 3141 reviews Next
Still got questions? Text our super-cool support team at 754-799-7833 to get help finding your ideal checkup.