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Aldosterone-renin ratio test for diagnosing blood pressure and kidney hormone issues

Blood Test for High Blood Pressure and Hormone Issues

Aldosterone/Plasma Renin Activity Ratio, LC/MS/MS

Google
3,138 reviews
  • Pinpoint the cause of your blood pressure issues
  • Reveal hidden hormonal imbalances affecting your health
  • Clarify the reasons behind your fatigue and dizziness
First results as soon as overnight*

90 day happiness guarantee

We stand behind our service

Prescription & fees included

Go directly to the lab, no extra fees

Easy to understand results

With friendly doctor's notes & guidance

Fast & convenient

Lab visit as quick as 10 mins in & out

90 day happiness guarantee

We stand behind our service

Prescription & fees included

Go directly to the lab, no extra fees

Easy to understand results

With friendly doctor's notes & guidance

Fast & convenient

Lab visit as quick as 10 mins in & out

What's this test for?

This test is ideal if you're experiencing unexplained high blood pressure, persistent fatigue, muscle weakness, or frequent dizziness. It helps identify hormonal imbalances in your renin-aldosterone system that could be causing your blood pressure issues or electrolyte problems. Many people use this test when their doctor suspects their hypertension has a hormonal cause rather than lifestyle factors alone.

How should I prepare for this test?

No fasting is needed for this test. However, your doctor may provide specific instructions about medication timing, especially if you take blood pressure medications, as some can affect renin and aldosterone levels. It's best to discuss any medications or supplements you're taking with your healthcare provider before testing.

What's included in this test?

Aldo/Pra Ratio Aldosterone, LC/MS/Ms Plasma Renin Activity, LC/MS/Ms

This panel measures Aldosterone (a hormone that regulates blood pressure and electrolytes), Plasma Renin Activity (an enzyme that controls aldosterone production), and the Aldo/PRA Ratio (which helps distinguish between different causes of high blood pressure). Together, these measurements help identify whether your blood pressure issues are caused by primary aldosteronism, secondary aldosteronism, renovascular hypertension, or other hormonal imbalances. This comprehensive evaluation is particularly useful for diagnosing hard-to-treat hypertension and understanding why you might be experiencing symptoms like fatigue, muscle weakness, or electrolyte abnormalities.

What happens after I get my results?
You'll receive detailed doctor notes in simple language explaining what your aldosterone and renin levels mean for your blood pressure and overall health. These notes include personalized recommendations like dietary changes (especially sodium intake), lifestyle modifications, or whether you should follow up with an endocrinologist or nephrologist. You'll also get the standard lab report and can track your hormone levels over time using our trends feature to monitor how treatments or interventions are affecting your blood pressure.
Who should consider getting this test?
This test is important for people with difficult-to-control high blood pressure, especially if you're taking multiple medications. It's also valuable if you have unexplained low potassium levels, muscle weakness, excessive thirst, or frequent urination. Anyone with a family history of early hypertension or adrenal disorders should also consider this screening.
What symptoms indicate I may need this test?
Common symptoms include persistent high blood pressure that doesn't respond well to standard treatments, unexplained fatigue or muscle weakness, frequent headaches, and episodes of dizziness. You might also experience excessive thirst, increased urination, heart palpitations, or muscle cramps. Some people notice they feel worse despite taking blood pressure medications as prescribed.
What is the aldosterone-renin ratio and why does it matter?
The aldosterone-renin ratio helps doctors determine why your blood pressure is elevated by comparing two key hormones in your blood pressure regulation system. When this ratio is abnormal, it can indicate primary aldosteronism (where your adrenal glands produce too much aldosterone) or other conditions affecting your kidneys and blood pressure. Understanding this ratio helps target the right treatment rather than just treating symptoms with standard blood pressure medications.
What does high aldosterone mean?
High aldosterone typically causes your body to retain sodium and lose potassium, leading to high blood pressure, low potassium levels, and fluid retention. This can result from overactive adrenal glands (primary aldosteronism) or be a response to kidney problems or low blood volume (secondary aldosteronism). The distinction helps your doctor determine whether the problem originates in your adrenal glands or elsewhere in your body.
What does low renin activity mean?
Low renin activity combined with high aldosterone suggests primary aldosteronism, meaning your adrenal glands are producing too much aldosterone independently. This is different from normal blood pressure regulation where renin and aldosterone work together. Low renin with high aldosterone indicates your body is trying to turn off aldosterone production by suppressing renin, but the adrenal glands aren't responding properly.
How often should I retest these hormone levels?
If you're being evaluated for a new diagnosis of hormone-related hypertension, your doctor may retest every few months initially to monitor treatment effectiveness. Once your condition is stable and well-managed, annual testing is typically sufficient for monitoring. If you're making significant lifestyle changes or adjusting medications, retesting every 3-6 months helps track your progress and ensure treatments are working.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.

Long story short:
  1. In the test options, use the filters or search box to narrow your choices and find the test you want.
  2. If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
  3. Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
  4. If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
  5. When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
  6. Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
  7. You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
  8. If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want. If you’re not sure which test to get, we can lend a hand in finding the right option.

Just text or call us at 754-799-7833, email us at [email protected], and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.

Just reach out to us via text at 754-799-7833 or shoot us an email at [email protected]. Remember to include your order number and let us know the correct information you’d like to update. Our awesome team will jump right in and make sure everything is sorted out and accurate for you.

There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.

Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.

Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.

This policy applies to all insurance companies, including federal health insurance programs like Medicare.

If you have any questions, please text us at 754-799-7833 or email [email protected].
Can I cancel my order?
Yes.

We get it – sometimes your needs change.

As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.

If you have any further questions, please text us at 754-799-7833 or email [email protected].

You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached! You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).

Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.

If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.

Here’s why 1,000,000+ customers chose us for affordable hassle-free private blood testing.

You get clinical lab reports & simplified health insights.
Save time & gas, go straight to the lab. Our doctors cover the rest.
Results start landing the next day after your lab visit.*
We don’t sell or share your data. Your time & privacy matter.
US-licensed doctors have your back if things get unclear.
No hidden fees, nice discounts for regular checkups.
Save a trip to the doctor, go directly to the lab
Instant orders, results often overnight*
Results explained in simple language
Reviewed by US licensed doctors
Fast & confidential, we never sell or share your data
No insurance needed, transparent pricing
Demo results
Aldosterone 28 ng/dL
Demo results
Low Optimal 4 - 20 High
28 ng/dL

What this means

Your aldosterone level is elevated above the optimal range, which may be contributing to high blood pressure and electrolyte imbalances. Elevated aldosterone causes your body to retain sodium and lose potassium, which can lead to symptoms like muscle weakness, fatigue, and persistent hypertension that's difficult to control with standard medications.

* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More complex tests, such as hormone panels, may take up to 10–15 business days due to their complexity.
Here’s how easy it is to get blood work done on your terms
Choose a checkup
Order your test Save a trip to the doctor. Your results will come with clear, friendly explanations. Takes 2 minutes
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Book an appointment Visit any of our 4,000 nearby lab locations to have your samples collected. Book or walk-in
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Get results Receive a clear, easy-to-digest health report by email & SMS within a few business days. Get answers, fast

Blood Test for High Blood Pressure and Hormone Issues

Google
3,138 reviews
  • Pinpoint the cause of your blood pressure issues
  • Reveal hidden hormonal imbalances affecting your health
  • Clarify the reasons behind your fatigue and dizziness

1,000,000+ blood tests later, here's what our customers say

Google reviews 3138 reviews Next
Still got questions? Text our super-cool support team at 754-799-7833 to get help finding your ideal checkup.