This test is ideal if you're struggling with stubborn weight gain that won't respond to diet and exercise, or if you're concerned about developing diabetes or heart disease. Adiponectin is a hormone that regulates how your body processes sugar and fat, and low levels are strongly linked to metabolic syndrome, insulin resistance, and cardiovascular problems. Many people use this test when they have risk factors for diabetes or heart disease and want to understand their metabolic health more deeply.
How should I prepare for this test?
Fasting:12 hours
You'll need to fast for 12 hours before your blood draw. This means no food or drinks except water during that time. Fasting ensures accurate measurement of your adiponectin levels without interference from recent meals. Schedule your test for the morning so you can fast overnight while you sleep.
What's included in this test?
Adiponectin(1)
This test measures Adiponectin, a protein hormone produced by fat cells that plays a crucial role in regulating glucose metabolism and insulin sensitivity. Low adiponectin levels are strongly associated with insulin resistance, metabolic syndrome, type 2 diabetes, and coronary artery disease, making it a valuable marker for assessing your risk of these conditions and monitoring the effectiveness of interventions.
What happens after I get my results?
You'll receive detailed doctor notes in simple language explaining what your adiponectin levels mean for your metabolic health, diabetes risk, and heart disease risk. These notes include personalized recommendations like dietary changes, exercise strategies, supplement suggestions, or whether you should consider medications that can increase adiponectin levels. You'll also get the standard lab report and can track your adiponectin levels over time using our trends feature to see how your lifestyle interventions or treatments are working.
Who should consider getting this test?
This test is valuable for anyone with risk factors for metabolic syndrome, including obesity, high blood pressure, high cholesterol, or a family history of diabetes. It's especially useful for people who struggle with weight loss despite healthy habits, those with insulin resistance or prediabetes, and individuals concerned about their heart disease risk. People already working on metabolic health improvements can use it to track their progress.
What symptoms indicate I may need this test?
Consider this test if you're experiencing unexplained weight gain, especially around your midsection, difficulty losing weight despite diet and exercise, constant sugar cravings, or fatigue after meals. Other indicators include having high blood pressure, abnormal cholesterol levels, darkened skin patches on your neck or armpits (acanthosis nigricans), or a family history of diabetes or heart disease. If you're experiencing these symptoms, testing adiponectin can provide valuable insights into your metabolic health.
How can I naturally increase my adiponectin levels?
Regular physical activity, especially aerobic exercise and strength training, can significantly increase adiponectin levels. Eating a diet rich in monounsaturated fats from foods like olive oil, avocados, and nuts, along with omega-3 fatty acids from fish, has been shown to boost adiponectin. Getting adequate sleep, managing stress, losing even modest amounts of weight if overweight, and including magnesium-rich foods like leafy greens and whole grains can also help improve adiponectin production.
What is adiponectin and why does it matter?
Adiponectin is a hormone produced by your fat cells that helps regulate how your body uses sugar and fat for energy. Unlike most hormones from fat tissue, adiponectin levels are actually lower in people who are overweight or obese. It acts as a protective hormone by improving insulin sensitivity, reducing inflammation, and protecting your heart and blood vessels. Higher levels are associated with better metabolic health and lower risk of diabetes and heart disease.
What does low adiponectin mean?
Low adiponectin levels indicate that your body may have difficulty regulating blood sugar and fat metabolism efficiently. This puts you at significantly higher risk for developing insulin resistance, type 2 diabetes, and metabolic syndrome. Research shows that people with low adiponectin are up to 9 times more likely to develop type 2 diabetes and have double the risk of coronary artery disease. Low levels are also associated with chronic inflammation and difficulty losing weight.
How often should I retest my adiponectin levels?
If you're actively making lifestyle changes or starting treatments to improve your metabolic health, retesting every 3-6 months can help you track your progress and see if your interventions are working. Once your levels stabilize in a healthy range, annual testing is reasonable for ongoing monitoring. If you're at high risk for diabetes or heart disease, your healthcare provider may recommend more frequent testing as part of comprehensive metabolic monitoring.
How’s this work?
Getting your blood test with us is easy, private & backed by the power of science.
Long story short:
In the test options, use the filters or search box to narrow your choices and find the test you want.
If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
Once your order is placed, we’ll create your doctor’s lab order remotely, without any need for you to make a trip to a doctor in person or to talk to the doctor. Expect to receive your doctor’s lab order right in your inbox. It will also be in your patient portal if you need to find it later. We’ll also include instructions regarding fasting and other requirements for your test. Your patient portal will be auto-created hassle-free during checkout.
If this is your first time ordering, you'll be prompted to create a password for instant login access to your patient portal. It's a quick way to conveniently access your orders and results whenever you want.
When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
Note that most lab locations don’t accept walk-ins, so it’s best to book an appointment in advance. Don’t worry – we’ll provide detailed instructions along the way.
You’ll get your results via email & SMS and dive into understanding your body better. Yup, that easy!
If you have any questions, please text us at 754-799-7833 or email [email protected] and we'll gladly help you.
How do I know which test to get?
In the test options, find the test you want.
If you’re not sure which test to get, we can lend a hand in finding the right option.
Just text or call us at 754-799-7833, email us at [email protected], and we'll gladly help you. We've got your back and reply quickly.
Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?
Absolutely! We totally understand that errors can happen. No worries, we're here to help you.
Just reach out to us via text at 754-799-7833 or shoot us an email at
[email protected]. Remember to include your order number and let us know the correct information you’d like to update.
Our awesome team will jump right in and make sure everything is sorted out and accurate for you.
There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.
Our lab requires an address to be listed to generate an order.
Do you accept health insurance?
Only HSA & FSA is accepted.
Our services are strictly self-pay and cannot be submitted to your health insurance provider except for Health Savings Accounts or Flexible Savings Accounts.
This policy applies to all insurance companies, including federal health insurance programs like Medicare.
You can read more about our cancellation policy here.
How can I find a lab location near me?
During the ordering process, you’ll be able to select a specific lab near you, with no strings attached!
You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).
Before you proceed with your order, feel free to browse through all our lab locations here. This will give you the peace of mind of knowing that there's a lab nearby your home, office or your favorite gym.
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Demo results
Adiponectin4.2 μg/mL
Demo results
LowOptimal 5.0 - 15.0High
4.2 μg/mL
What this means
Your adiponectin level is below the optimal range, which may indicate decreased insulin sensitivity and increased risk for metabolic syndrome. Low adiponectin is associated with difficulty losing weight, increased inflammation, and higher risk of developing type 2 diabetes and heart disease over time.
Recommended actions
Incorporate regular aerobic exercise like brisk walking or swimming at least 30 minutes daily
Include more monounsaturated fats from olive oil, avocados, and nuts in your diet
Prioritize 7-8 hours of quality sleep and practice stress management techniques
Consider retesting in 3-6 months after implementing lifestyle changes
* Regular blood test results (e.g., CBC) typically start arriving the next business day after sample collection. More complex tests, such as hormone panels, may take up to 10–15 business days due to their complexity.
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Adiponectin Test for Weight Gain and Diabetes Risk