Understanding Lab Tests for Wilms' Tumor
Written by Private MD Labs Medical Writing Team • Last Updated: September 8, 2025
Wilms' tumor is a rare type of kidney cancer that primarily affects children, typically diagnosed between ages 3 and 4. The diagnosis is typically made through imaging studies and tissue examination. While there isn't a single blood test to diagnose Wilms' tumor itself, laboratory testing plays an important role in understanding the genetic factors associated with this condition and monitoring the body's response during treatment.
Recommended Test
IGF-2
This test measures insulin-like growth factor 2 (IGF-2) levels in the blood. Elevated IGF-2 levels have been linked to the development of Wilms' tumor, as this rare kidney cancer is often associated with genetic changes that result in overexpression of the IGF-2 gene. Monitoring these levels can provide insight into the tumor's biological characteristics and potential genetic factors involved.
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Why Blood Testing is Important for Wilms' Tumor
Blood tests are fundamental for assessing genetic markers that may be associated with tumor development, monitoring overall health during treatment, and evaluating the body's response to therapy. Certain proteins and growth factors can provide valuable information about the biological characteristics of the tumor.
Understanding the Results
IGF-2 testing helps healthcare providers understand the genetic aspects of Wilms' tumor development. While elevated levels are associated with this condition, the test results must be interpreted alongside clinical findings and imaging studies for comprehensive patient care.
Important Considerations
The information here is for educational purposes only and is not a substitute for professional medical advice. Always consult with a healthcare provider for diagnosis and treatment of Wilms' tumor or any suspected kidney condition in children.
