Understanding Lab Tests for Visceral Leishmaniasis
Written by Private MD Labs Medical Writing Team • Last Updated: September 8, 2025
Visceral leishmaniasis, also known as kala-azar, is a severe systemic parasitic infection caused by Leishmania species. This life-threatening condition affects internal organs including the spleen, liver, and bone marrow, requiring prompt diagnosis and treatment.
Recommended Test
Leishmania Antibody (IgG)
This blood test detects IgG antibodies that the immune system produces in response to Leishmania parasites. High levels of Leishmania antibodies indicate a systemic infection affecting internal organs such as the spleen, liver, and bone marrow, which is characteristic of visceral leishmaniasis.
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Diagnosing Visceral Leishmaniasis
Because visceral leishmaniasis can present with non-specific symptoms like fever, weight loss, and fatigue that overlap with other conditions, accurate laboratory testing is essential for definitive diagnosis. Blood tests can detect the body's immune response to the Leishmania parasite.
Understanding Your Results
A positive Leishmania antibody test indicates exposure to and infection with Leishmania parasites. High antibody levels are particularly significant in visceral leishmaniasis, as they reflect the body's response to widespread parasitic invasion of internal organs. Early detection is crucial for preventing serious complications.
Important Considerations
The information here is for educational purposes only and is not a substitute for professional medical advice. Visceral leishmaniasis is a serious condition that requires immediate medical attention. Always consult with a healthcare provider for diagnosis and treatment.
