Sample results
Viral hepatitis is an infection that causes inflammation and damage to the liver. It is caused by specific viruses including hepatitis A virus (HAV), hepatitis B virus (HBV), hepatitis C virus (HCV), hepatitis D virus (HDV), and hepatitis E virus (HEV). The Hepatitis Viral Panel with Liver Function Tests is the most important test for diagnosis because it detects viral antigens, antibodies, and genetic material while assessing liver damage.
Viral hepatitis is caused by five distinct viruses: hepatitis A virus (HAV), hepatitis B virus (HBV), hepatitis C virus (HCV), hepatitis D virus (HDV), and hepatitis E virus (HEV). Each virus transmits differently - HAV and HEV spread through contaminated food or water, while HBV, HCV, and HDV spread through blood and bodily fluids. These viruses attack liver cells, triggering inflammation that can lead to acute illness or chronic liver disease depending on the virus type and your immune response.
The Hepatitis Viral Panel is the most important test for viral hepatitis because it detects specific antigens, antibodies, and viral genetic material (DNA/RNA) for each hepatitis virus. This comprehensive panel identifies which virus is present and determines whether the infection is acute or chronic. Additional liver function tests measure enzymes like ALT and AST to assess liver damage, while the Smooth Muscle Antibody with Reflex to Titer helps rule out autoimmune hepatitis if your results are unclear. Together, these tests provide a complete picture of your liver health and guide appropriate treatment.
You should get tested if you experience yellowing of your skin or eyes (jaundice), persistent fatigue, dark urine, pale stools, or abdominal pain in your upper right side. Testing is also essential if you have known exposure to someone with hepatitis, share needles, have multiple sexual partners, received a blood transfusion before 1992, or traveled to regions where hepatitis is common. Healthcare workers, people with HIV, and anyone born between 1945-1965 should get tested as they face higher risk for chronic hepatitis infections.
What this means
Your test came back negative, meaning no smooth muscle antibodies were detected in your blood. This is the expected and healthy result, making autoimmune hepatitis unlikely as the cause of any symptoms you may be experiencing.
Recommended actions
Continue monitoring liver health with regular wellness checkups
Discuss other potential causes of symptoms with your doctor if fatigue or discomfort persists
Maintain a balanced diet and limit alcohol to support liver function
Consider retesting if new liver-related symptoms develop or liver enzyme levels become elevated
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Sample results
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