Understanding Lab Tests for Uveitis
Written by Private MD Labs Medical Writing Team • Last Updated: September 8, 2025
Uveitis is an inflammation of the uvea, the middle layer of the eye that includes the iris, ciliary body, and choroid. While uveitis is primarily diagnosed through comprehensive eye examination by an ophthalmologist, blood testing plays a crucial supporting role in identifying underlying causes and associated conditions that may contribute to this inflammatory eye condition.
Top Recommended Test
HLA-B27 Antigen
This test detects the presence of HLA-B27 antigen, a genetic marker associated with increased risk of developing uveitis. Studies have shown a higher prevalence of this antigen in patients with uveitis, making it valuable for identifying genetic predisposition to this inflammatory eye condition.
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Why Blood Testing is Important for Uveitis
Although there isn't a single blood test to diagnose uveitis itself, laboratory testing is fundamental for uncovering potential underlying causes, infections, or genetic predispositions that may trigger or contribute to the development of uveitis. This information helps healthcare providers develop targeted treatment strategies and monitor for associated systemic conditions.
Other Relevant Tests
HLA B Low Resolution
This broader HLA-B typing test includes detection of HLA-B27, which is associated with uveitis development. People who are HLA-B27 positive have a higher risk of developing this eye inflammation, making this test useful for risk assessment and understanding genetic factors.
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Human T-Cell Lymphotropic Virus I, II (HTLV-I/HTLV-II), Qualitative
This test detects HTLV-I/II DNA to identify active viral infection. HTLV-I infection can sometimes lead to uveitis as a complication, making this test important for identifying viral causes of eye inflammation and guiding appropriate antiviral treatment strategies.
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Human T-Cell Lymphotropic Virus I, II (HTLV-I/HTLV-II) Antibodies, Preliminary Test W/ Confirmation
This test detects antibodies against HTLV-I/II viruses, indicating past or current infection. Since uveitis can be associated with HTLV-I infection, detecting these antibodies is crucial for identifying this potential infectious cause and determining appropriate treatment approaches for virus-related eye inflammation.
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Understanding Your Results
These blood tests help identify specific risk factors and potential causes of uveitis rather than diagnosing the eye condition itself. Positive results for HLA-B27 indicate genetic predisposition, while positive HTLV results suggest an infectious cause that may require specific treatment. Your healthcare provider will interpret these results alongside your eye examination findings to develop the most appropriate treatment plan.
Important Considerations
The information here is for educational purposes only and is not a substitute for professional medical advice. Always consult with a healthcare provider for diagnosis and treatment.
