Question 1

What is Uveitis?

Accepted Answer

Uveitis is an inflammation of the uvea, the middle layer of the eye that includes the iris, ciliary body, and choroid. It is caused by genetic factors like HLA-B27 antigen, infections such as Human T-Cell Lymphotropic Virus (HTLV), or autoimmune conditions. The HLA-B27 Antigen test is the most important test for identifying genetic predisposition to uveitis.

Question 2

What causes uveitis?

Accepted Answer

Uveitis is caused by genetic factors, infections, autoimmune diseases, and inflammatory conditions. The HLA-B27 antigen is a genetic marker strongly associated with developing uveitis, particularly anterior uveitis affecting the front of the eye. Infections like Human T-Cell Lymphotropic Virus type I (HTLV-I), toxoplasmosis, herpes viruses, and tuberculosis can trigger eye inflammation. Autoimmune conditions such as rheumatoid arthritis, ankylosing spondylitis, and inflammatory bowel disease are also common causes of uveitis.

Question 3

What is the best test for uveitis?

Accepted Answer

The HLA-B27 Antigen test is the most important blood test for uveitis because it identifies genetic predisposition to this inflammatory eye condition. Studies show a significantly higher prevalence of HLA-B27 in patients with uveitis, especially those with acute anterior uveitis. If viral infection is suspected, the Human T-Cell Lymphotropic Virus I, II (HTLV-I/HTLV-II) Antibodies test is essential for detecting HTLV-related uveitis. The HLA B Low Resolution test provides broader genetic typing that includes HLA-B27 and can reveal additional genetic risk factors. These tests help identify underlying causes and guide your doctor toward the most effective treatment approach.

Question 4

When should I get tested for uveitis?

Accepted Answer

You should get tested if you experience eye redness, pain, blurred vision, light sensitivity, or floaters that do not improve quickly. Testing is especially important if you have recurrent episodes of eye inflammation, a family history of uveitis or autoimmune diseases, or known conditions like ankylosing spondylitis or inflammatory bowel disease. If you have persistent eye discomfort lasting more than a few days or sudden vision changes, blood testing can help identify genetic factors or infections contributing to your symptoms and prevent potential vision loss.

Question 5

What are the symptoms of uveitis?

Accepted Answer

Uveitis symptoms include eye redness, pain, blurred or decreased vision, and sensitivity to light (photophobia). You might notice floaters appearing as dark spots or squiggly lines in your vision. The affected eye may feel tender or achy, and you may experience tearing or excessive discharge. Symptoms can develop suddenly and worsen rapidly, or they may come on gradually. Some people experience recurrent episodes with periods of remission. If you notice any combination of these symptoms, especially sudden vision changes or severe eye pain, seek evaluation promptly to prevent complications.

Question 6

Who is at risk for uveitis?

Accepted Answer

People with the HLA-B27 genetic marker have significantly higher risk of developing uveitis. Those with autoimmune conditions like rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, lupus, or inflammatory bowel disease are at increased risk. Individuals with infections such as HTLV-I, tuberculosis, syphilis, toxoplasmosis, or herpes viruses can develop uveitis as a complication. Smokers have higher risk, and uveitis can affect people of any age, though certain types are more common in young to middle-aged adults. A family history of uveitis or autoimmune diseases also increases your susceptibility.

Question 7

What happens if uveitis is left untreated?

Accepted Answer

Untreated uveitis can lead to serious and permanent vision complications. You may develop glaucoma from increased eye pressure, cataracts causing clouding of the lens, retinal swelling or detachment, and permanent vision loss or blindness. Chronic inflammation can damage the optic nerve and other delicate eye structures. The condition may spread to other parts of the eye, worsening the inflammation and increasing the risk of complications. Early detection through blood testing to identify underlying causes, combined with prompt treatment, is crucial for preserving your vision and preventing irreversible damage to your eyes.

Question 8

Can uveitis be diagnosed with a blood test?

Accepted Answer

Blood tests cannot diagnose uveitis directly, but they play a crucial supporting role in identifying underlying causes and risk factors. The HLA-B27 Antigen test reveals genetic predisposition, while HTLV antibody tests detect viral infections that may trigger uveitis. Your eye doctor will diagnose uveitis through a comprehensive eye examination using specialized equipment to view the inside of your eye. Blood tests complement the eye exam by uncovering infections, autoimmune markers, and genetic factors that explain why the inflammation developed. This information helps your healthcare team create a targeted treatment plan and monitor for related systemic conditions.

Question 9

How is uveitis treated?

Accepted Answer

Uveitis treatment depends on the underlying cause identified through testing. Corticosteroid eye drops, injections, or oral medications reduce inflammation and prevent damage. If blood tests reveal HLA-B27 positivity or autoimmune conditions, immunosuppressive medications may be prescribed to control the immune response. For infectious causes like HTLV or herpes viruses, antiviral or antibiotic medications target the specific infection. Dilating eye drops help reduce pain and prevent complications. In severe or chronic cases, biologic medications or surgical interventions may be necessary. Your treatment plan is tailored based on blood test results, the type and location of inflammation, and your overall health.

Question 10

How can I prevent uveitis?

Accepted Answer

Preventing uveitis focuses on managing risk factors and treating underlying conditions. If you have autoimmune diseases, maintaining consistent treatment helps prevent inflammation from affecting your eyes. Protect yourself from infections by practicing good hygiene, avoiding exposure to infectious diseases, and seeking prompt treatment for infections. If you are HLA-B27 positive, regular monitoring and early intervention at the first signs of eye inflammation can prevent severe episodes. Avoid smoking, which increases uveitis risk. Wear protective eyewear to prevent eye injuries that can trigger inflammation. Regular eye exams help detect early signs of inflammation before symptoms become severe.

Question 11

What can I do at home for uveitis?

Accepted Answer

While professional medical treatment is essential for uveitis, you can support your eye health at home with several strategies. Wear sunglasses to reduce light sensitivity and protect your eyes from bright light and UV exposure. Apply cool compresses to your closed eyes to soothe discomfort and reduce swelling. Rest your eyes frequently if you experience blurred vision or eye strain. Maintain a healthy diet rich in omega-3 fatty acids, vitamins A, C, and E, and antioxidants to support eye health and reduce inflammation. Avoid rubbing your eyes, which can worsen inflammation. Follow your prescribed medication schedule carefully and attend all follow-up appointments to monitor your condition and prevent complications.

Question 12

How’s this work?

Accepted Answer

Getting your blood test with us is easy, private & backed by the power of science.Long story short:
            
                In the test options, use the filters or search box to narrow your choices and find the test you want.
                If you need a hand navigating through options, text our super friendly support team at 754-799-7833, and we'll provide tailored suggestions to help you find the ideal test.
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                When you’re ready, visit one of our 4,000 locations. Just bring your ID – no printing or faxing of your lab order is needed, as your order and details will already be in the lab system.
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Question 13

How do I know which test to get?

Accepted Answer

In the test options, find the test you want.
            If you’re not sure which test to get, we can lend a hand in finding the right option.
            Just text or call us at 754-799-7833, email us at support@privatemdlabs.com, and we'll gladly help you. We've got your back and reply quickly.

Question 14

When will my lab results be available?

Accepted Answer

Most test results will be available within 1–3 business days. Once they're ready, we'll send an email and text message to let you know.
            After your blood draw, just hang tight and don't worry – we'll keep you updated and in the loop!
            If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com, and we'll gladly help you.

Question 15

Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?

Accepted Answer

Absolutely! We totally understand that errors can happen. No worries, we're here to help you.
            Just reach out to us via text at 754-799-7833 or shoot us an email at
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            There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.
            Our lab requires an address to be listed to generate an order.

Question 16

Do you accept health insurance?

Accepted Answer

Only HSA & FSA is accepted.
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Question 17

Can I cancel my order?

Accepted Answer

Yes.
            We get it – sometimes your needs change.
            As long as your samples haven’t been collected yet, we’re happy to help you cancel your order.
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            You can read more about our cancellation policy here.

Question 18

How can I find a lab location near me?

Accepted Answer

During the ordering process, you’ll be able to select a specific lab near you, with no strings attached!
            You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).
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Uveitis Blood Test

What is Uveitis?

What causes uveitis?

What is the best test for uveitis?

When should I get tested for uveitis?

References

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